Dabrafenib KINOMEscan - Dataset (ID:20131)
Proteins Studied
Download: Excel (XLSX), Comma-separated (CSV)
| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 200214 | KIT | 200214 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | Wild Type; Partial length | |||
| 200238 | MAP3K3 | 200238 | Q99759 | Mitogen-activated protein kinase kinase kinase 3; MAP3K3; MAPKKK3; MEKK3; MEKK3/MAP3K3 | KINOMEscan | Wild Type; Partial length | |||
| 200079 | CDK5 | 200079 | Q00535 | Cyclin-dependent kinase 5; cell division protein kinase 5; PSSALRE | KINOMEscan | Wild Type; Full length | |||
| 200044 | AURKA | 200044 | O14965 | Aurora kinase A; AIK; AIRK1; ARK1; Aur2; AURA; AurA/Aur2; AURKA; AURORA2; Aurora-A; Ayk1; BTAK; IAK; IAK1; MGC34538; STK15; STK6; STK7 | KINOMEscan | Wild Type; Partial length | |||
| 200147 | EPHB6 | 200147 | O15197 | EPH receptor B6; EPHB6; HEP; MGC129910; MGC129911 | KINOMEscan | Wild Type; Partial length | |||
| 200146 | EPHB4 | 200146 | P54760 | Ephrin type-B receptor 4; EPHB4; HTK; MYK1; TYRO11 | KINOMEscan | Wild Type; Partial length | |||
| 200078 | CDK4-cyclinD3 | 200078 | P11802 | Cyclin-dependent kinase 4; cell division protein kinase 4 | KINOMEscan | Wild Type; Full length | |||
| 200145 | EPHB3 | 200145 | P54753 | Ephrin type-B receptor 3; EPHB3; ETK2; HEK2; TYRO6 | KINOMEscan | Wild Type; Partial length | |||
| 200144 | EPHB2 | 200144 | P29323 | Ephrin type-B receptor 2; CAPB; DRT; EK5; EPHB2; EPHT3; ERK; Hek5; MGC87492; PCBC; Tyro5 | KINOMEscan | Wild Type; Partial length | |||
| 200222 | LATS1 | 200222 | O95835 | LATS, large tumor suppressor, homolog 1 (Drosophila); LATS1; WARTS; wts | KINOMEscan | Wild Type; Partial length | |||
| 200223 | LATS2 | 200223 | Q9NRM7 | LATS, large tumor suppressor, homolog 2 (Drosophila); FLJ13161; KPM; LATS2 | KINOMEscan | Wild Type; Partial length | |||
| 200224 | LCK | 200224 | P06239 | Lymphocyte-specific protein tyrosine kinase; LCK; LSK; p56lck; pp58lck; YT16 | KINOMEscan | Wild Type; Partial length | |||
| 200225 | LIMK1 | 200225 | P53667 | LIM domain kinase 1; LIMK | KINOMEscan | Wild Type; Full length | |||
| 200226 | LIMK2 | 200226 | P53671 | LIM domain kinase 2; LIMK2 | KINOMEscan | Wild Type; Full length | |||
| 200227 | LKB1 | 200227 | Q15831 | Serine/threonine kinase 11; LKB1; PJS; STK11 | KINOMEscan | Wild Type; Full length | |||
| 200228 | LOK | 200228 | O94804 | Serine/threonine-protein kinase 10 | KINOMEscan | Wild Type; Partial length | |||
| 200229 | LRRK2 | 200229 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2; AURA17; DARDARIN; LRRK2; PARK8; RIPK7; ROCO2 | KINOMEscan | Wild Type; Partial length | |||
| 200077 | CDK4-cyclinD1 | 200077 | P11802 | Cyclin-dependent kinase 4; cell division protein kinase 4 | KINOMEscan | Wild Type; Full length | |||
| 200231 | LTK | 200231 | P29376 | Leukocyte receptor tyrosine kinase; LTK; TYK1 | KINOMEscan | Wild Type; Partial length | |||
| 200232 | LYN | 200232 | P07948 | V-yes-1 Yamaguchi sarcoma viral related oncogene homolog; FLJ26625; JTK8; LYN | KINOMEscan | Wild Type; Partial length | |||
| 200233 | M3K13 | 200233 | O43283 | Mitogen-activated protein kinase kinase kinase 13; LZK; MAP3K13; MEKK13; MGC133196 | KINOMEscan | Wild Type; Full length | |||
| 200234 | MAK | 200234 | P20794 | Male germ cell-associated kinase; dJ417M14.2; MAK | KINOMEscan | Wild Type; Partial length | |||
| 200043 | M3K6 | 200043 | O95382 | Mitogen-activated protein kinase kinase kinase 6; ASK2; MAP3K6; MAPKKK6; MEKK6; MEKK6/MAP3K6; MGC125653; MGC20114 | KINOMEscan | Wild Type; Partial length | |||
| 200143 | EPHB1 | 200143 | P54762 | Ephrin type-B receptor 1; ELK; EPHB1; EPHT2; FLJ37986; Hek6; NET | KINOMEscan | Wild Type; Partial length | |||
| 200142 | EPHA8 | 200142 | P29322 | EPH receptor A8; EEK; EK3; EPHA8; HEK3; KIAA1459 | KINOMEscan | Wild Type; Partial length |