Dabrafenib KINOMEscan - Dataset (ID:20131)

Proteins Studied

LINCS ID Name HMS LINCS ID UniProt ID Alternative Names Provider Mutation Phosphlorylation State Domain Protein Description
200280 MYLK2 200280 Q9H1R3
Myosin light chain kinase 2; KMLC; MLCK; MLCK2; MYLK2; skMLCK
KINOMEscan Wild Type; Partial length
200266 MLCK 200266 Q32MK0
Myosin light chain kinase 3; caMLCK; MGC126319; MGC126320; MLCK; MLCK2; MYLK3
KINOMEscan Wild Type; Partial length
200279 MYLK 200279 Q15746
Myosin light chain kinase; DKFZp686I10125; FLJ12216; KRP; MLCK; MLCK1; MLCK108; MLCK210; MSTP083; MYLK; MYLK1; smMLCK
KINOMEscan Wild Type; Full length
200281 MYLK4 200281 Q86YV6
Myosin light chain kinase family, member 4; MYLK4; SgK085
KINOMEscan Wild Type; Partial length
200115 DMPK 200115 Q09013
Myotonin-protein kinase; Dystrophia myotonica-protein kinase; DM; DM1; DM1PK; DMK; MDPK; MT-PK
KINOMEscan Wild Type; Partial length
200443 TRKA 200443 P04629
Neurotrophic tyrosine kinase, receptor, type 1; DKFZp781I14186; MTC; NTRK1; p140-TrkA; TRK; TRK1; TRKA; Trk-A
KINOMEscan Wild Type; Partial length
200444 TRKB 200444 Q16620
Neurotrophic tyrosine kinase, receptor, type 2; GP145-TrkB; NTRK2; TRKB
KINOMEscan Wild Type; Partial length
200445 TRKC 200445 Q16288
Neurotrophic tyrosine kinase, receptor, type 3; gp145(trkC); NTRK3; TRKC
KINOMEscan Wild Type; Partial length
200481 NEK10 200481 Q6ZWH5
NIMA (never in mitosis gene a)- related kinase 10
KINOMEscan
200287 NEK11 200287 Q8NG66
NIMA (never in mitosis gene a)-related kinase 11; FLJ23495; NEK11
KINOMEscan Wild Type; Partial length
200286 NEK1 200286 Q96PY6
NIMA (never in mitosis gene a)-related kinase 1; DKFZp686D06121; DKFZp686K12169; KIAA1901; MGC138800; NEK1; NY-REN-55
KINOMEscan Wild Type; Partial length
200289 NEK3 200289 P51956
NIMA (never in mitosis gene a)-related kinase 3; HSPK36; MGC29949; NEK3
KINOMEscan Wild Type; Full length
200290 NEK4 200290 P51957
NIMA (never in mitosis gene a)-related kinase 4; MGC33171; NEK4; NRK2; pp12301; STK2
KINOMEscan Wild Type; Full length
200291 NEK5 200291 Q6P3R8
NIMA (never in mitosis gene a)-related kinase 5; MGC75495; NEK5
KINOMEscan Wild Type; Partial length
200292 NEK6 200292 Q9HC98
NIMA (never in mitosis gene a)-related kinase 6; NEK6; SID6-1512
KINOMEscan Wild Type; Full length
200293 NEK7 200293 Q8TDX7
NIMA (never in mitosis gene a)-related kinase 7; NEK7
KINOMEscan Wild Type; Full length
200294 NEK9 200294 Q8TD19
NIMA (never in mitosis gene a)-related kinase 9; DKFZp434D0935; MGC138306; MGC16714; Nek8; NEK9; NERCC; NERCC1
KINOMEscan Wild Type; Partial length
200440 TNK1 200440 Q13470
Non-receptor tyrosine-protein kinase TNK1; MGC46193; TNK1
KINOMEscan Wild Type; Full length
200450 TYK2(JH1domain-catalytic) 200450 P29597
Non-receptor tyrosine-protein kinase TYK2; Tyrosine kinase 2; JTK1; TYK2
KINOMEscan JH1domain-catalytic Wild Type; Partial length
200451 TYK2(JH2domain-pseudokinase) 200451 P29597
Non-receptor tyrosine-protein kinase TYK2; Tyrosine kinase 2; JTK1; TYK2
KINOMEscan JH2domain-pseudokinase Wild Type; Partial length
200041 NUAK1 200041 O60285
NUAK family, SNF1-like kinase, 1; ARK5; KIAA0537; NUAK1
KINOMEscan Wild Type; Partial length
200413 SNARK 200413 Q9H093
NUAK family, SNF1-like kinase, 2; DKFZp434J037; DKFZp686F01113; FLJ90349; NUAK2; SNARK
KINOMEscan Wild Type; Partial length
200302 PAK1 200302 Q13153
P21 protein (Cdc42/Rac)-activated kinase 1; MGC130000; MGC130001; PAK1; PAKalpha
KINOMEscan Wild Type; Partial length
200303 PAK2 200303 Q13177
P21 protein (Cdc42/Rac)-activated kinase 2; PAK2; PAK65; PAKgamma
KINOMEscan Wild Type; Partial length
200304 PAK3 200304 O75914
P21 protein (Cdc42/Rac)-activated kinase 3; bPAK; CDKN1A; hPAK3; MRX30; MRX47; OPHN3; PAK3; PAK3beta
KINOMEscan Wild Type; Full length