Dabrafenib KINOMEscan - Dataset (ID:20131)
Proteins Studied
Download: Excel (XLSX), Comma-separated (CSV)
| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 200394 | RPS6KA5(Kin.Dom.1-N-terminal) | 200394 | O75582 | Ribosomal protein S6 kinase, 90kDa, polypeptide 5; MGC1911; MSK1; MSPK1; RLPK; RPS6KA5 | KINOMEscan | Kin.Dom.1-N-terminal | Wild Type; Partial length | ||
| 200157 | ERN1 | 200157 | O75460 | Endoplasmic reticulum to nucleus signaling 1; ERN1; FLJ30999; hIRE1p; IRE1; IRE1a; IRE1P; MGC163277; MGC163279 | KINOMEscan | Wild Type; Partial length | |||
| 200455 | ULK1 | 200455 | O75385 | Serine/threonine-protein kinase ULK1; Unc-51-like kinase 1 (C. elegans); ATG1; FLJ38455; FLJ46475; ULK1; UNC51; Unc51.1 | KINOMEscan | Wild Type; Partial length | |||
| 200382 | ROCK2 | 200382 | O75116 | Rho-associated protein kinase 2; Rho-associated, coiled-coil containing protein kinase 2; KIAA0619; ROCK2 | KINOMEscan | Wild Type; Partial length | |||
| 200207 | JAK2(JH1domain-catalytic) | 200207 | O60674 | Janus kinase 2; JAK2; JAK2-catalytic; JTK10 | KINOMEscan | JH1domain-catalytic | Wild Type; Partial length | ||
| 200341 | PIP5K1C | 200341 | O60331 | Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma; KIAA0589; LCCS3; PIP5K1C; PIP5Kgamma; PIP5K-GAMMA; PIPKIg_v4 | KINOMEscan | Wild Type; Partial length | |||
| 200041 | NUAK1 | 200041 | O60285 | NUAK family, SNF1-like kinase, 1; ARK5; KIAA0537; NUAK1 | KINOMEscan | Wild Type; Partial length | |||
| 200378 | RIPK2 | 200378 | O43353 | Receptor-interacting serine/threonine-protein kinase 2; CARD3; CARDIAK; CCK; GIG30; RICK; RIP2; RIPK2 | KINOMEscan | Wild Type; Partial length | |||
| 200426 | TAK1 | 200426 | O43318 | Mitogen-activated protein kinase kinase kinase 7; MAP3K7; MEKK7; TAK1; TGF1a | KINOMEscan | Wild Type; Partial length | |||
| 200108 | DAPK3 | 200108 | O43293 | Death-associated protein kinase 3; DAPK3; FLJ36473; ZIP; ZIPK | KINOMEscan | Wild Type; Partial length | |||
| 200233 | M3K13 | 200233 | O43283 | Mitogen-activated protein kinase kinase kinase 13; LZK; MAP3K13; MEKK13; MGC133196 | KINOMEscan | Wild Type; Full length | |||
| 200314 | PDPK1 | 200314 | O15530 | 3-phosphoinositide dependent protein kinase-1; MGC20087; MGC35290; PDK1; PDPK1; PRO0461 | KINOMEscan | Wild Type; Full length | |||
| 200300 | MK13 | 200300 | O15264 | Mitogen-activated protein kinase 13; MAPK13; MGC99536; p38d; p38delta; p38-delta; PRKM13; SAPK4 | KINOMEscan | Wild Type; Full length | |||
| 200147 | EPHB6 | 200147 | O15197 | EPH receptor B6; EPHB6; HEP; MGC129910; MGC129911 | KINOMEscan | Wild Type; Partial length | |||
| 200278 | MUSK | 200278 | O15146 | Muscle, skeletal, receptor tyrosine kinase; MGC126323; MGC126324; MUSK | KINOMEscan | Wild Type; Partial length | |||
| 200194 | IKKA | 200194 | O15111 | Inhibitor of nuclear factor kappa-B kinase subunit alpha | KINOMEscan | Wild Type; Full length | |||
| 200109 | DCLK1 | 200109 | O15075 | Serine/threonine-protein kinase DCLK1; CL1; CLICK1; DCAMKL1; DCDC3A; DCLK; DCLK1; KIAA0369 | KINOMEscan | Wild Type; Partial length | |||
| 200178 | GAK | 200178 | O14976 | Cyclin G associated kinase; FLJ16629; FLJ40395; GAK; MGC99654 | KINOMEscan | Wild Type; Partial length | |||
| 200044 | AURKA | 200044 | O14965 | Aurora kinase A; AIK; AIRK1; ARK1; Aur2; AURA; AurA/Aur2; AURKA; AURORA2; Aurora-A; Ayk1; BTAK; IAK; IAK1; MGC34538; STK15; STK6; STK7 | KINOMEscan | Wild Type; Partial length | |||
| 200070 | CASK | 200070 | O14936 | Calcium/calmodulin-dependent serine protein kinase (MAGUK family); CAGH39; CAMGUK; CASK; CMG; FGS4; FLJ22219; FLJ31914; LIN2; MICPCH; TNRC8 | KINOMEscan | Wild Type; Partial length | |||
| 200195 | IKKB | 200195 | O14920 | Inhibitor of nuclear factor kappa-B kinase subunit beta | KINOMEscan | Wild Type; Full length | |||
| 200087 | CHEK1 | 200087 | O14757 | CHK1 checkpoint homolog (S. pombe); CHEK1; CHK1 | KINOMEscan | Wild Type; Partial length | |||
| 200263 | MP2K7 | 200263 | O14733 | Dual specificity mitogen-activated protein kinase kinase 7; MKK7 | KINOMEscan | Wild Type; Full length | |||
| 200376 | RIOK3 | 200376 | O14730 | RIO kinase 3 (yeast); DKFZp779L1370; RIOK3; SUDD | KINOMEscan | Wild Type; Full length | |||
| 200089 | CIT | 200089 | O14578 | Citron (rho-interacting, serine/threonine kinase 21); CIT; CRIK; KIAA0949; STK21 | KINOMEscan | Wild Type; Partial length |