Dabrafenib KINOMEscan - Dataset (ID:20131)
Proteins Studied
Download: Excel (XLSX), Comma-separated (CSV)
| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 200214 | KIT | 200214 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | Wild Type; Partial length | |||
| 200215 | KIT(A829P) | 200215 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | A829P | Mutation (A829P); Partial length | ||
| 200216 | KIT(D816H) | 200216 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | D816H | Mutation (D816H); Partial length | ||
| 200217 | KIT(D816V) | 200217 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | D816V | Mutation (D816V); Partial length | ||
| 200218 | KIT(L576P) | 200218 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | L576P | Mutation (L576P); Partial length | ||
| 200219 | KIT(V559D) | 200219 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | V559D | Mutation (V559D); Partial length | ||
| 200220 | KIT(V559D,T670I) | 200220 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | V559D,T670I | Mutation (V559D,T670I); Partial length | ||
| 200221 | KIT(V559D,V654A) | 200221 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | V559D,V654A | Mutation (V559D,V654A); Partial length | ||
| 200222 | LATS1 | 200222 | O95835 | LATS, large tumor suppressor, homolog 1 (Drosophila); LATS1; WARTS; wts | KINOMEscan | Wild Type; Partial length | |||
| 200223 | LATS2 | 200223 | Q9NRM7 | LATS, large tumor suppressor, homolog 2 (Drosophila); FLJ13161; KPM; LATS2 | KINOMEscan | Wild Type; Partial length | |||
| 200224 | LCK | 200224 | P06239 | Lymphocyte-specific protein tyrosine kinase; LCK; LSK; p56lck; pp58lck; YT16 | KINOMEscan | Wild Type; Partial length | |||
| 200225 | LIMK1 | 200225 | P53667 | LIM domain kinase 1; LIMK | KINOMEscan | Wild Type; Full length | |||
| 200226 | LIMK2 | 200226 | P53671 | LIM domain kinase 2; LIMK2 | KINOMEscan | Wild Type; Full length | |||
| 200227 | LKB1 | 200227 | Q15831 | Serine/threonine kinase 11; LKB1; PJS; STK11 | KINOMEscan | Wild Type; Full length | |||
| 200228 | LOK | 200228 | O94804 | Serine/threonine-protein kinase 10 | KINOMEscan | Wild Type; Partial length | |||
| 200229 | LRRK2 | 200229 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2; AURA17; DARDARIN; LRRK2; PARK8; RIPK7; ROCO2 | KINOMEscan | Wild Type; Partial length | |||
| 200230 | LRRK2(G2019S) | 200230 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2; AURA17; DARDARIN; LRRK2; PARK8; RIPK7; ROCO2 | KINOMEscan | G2019S | Mutation (G2019S); Partial length | ||
| 200231 | LTK | 200231 | P29376 | Leukocyte receptor tyrosine kinase; LTK; TYK1 | KINOMEscan | Wild Type; Partial length | |||
| 200232 | LYN | 200232 | P07948 | V-yes-1 Yamaguchi sarcoma viral related oncogene homolog; FLJ26625; JTK8; LYN | KINOMEscan | Wild Type; Partial length | |||
| 200233 | M3K13 | 200233 | O43283 | Mitogen-activated protein kinase kinase kinase 13; LZK; MAP3K13; MEKK13; MGC133196 | KINOMEscan | Wild Type; Full length | |||
| 200234 | MAK | 200234 | P20794 | Male germ cell-associated kinase; dJ417M14.2; MAK | KINOMEscan | Wild Type; Partial length | |||
| 200235 | MAP3K1 | 200235 | Q13233 | Mitogen-activated protein kinase kinase kinase 1; MAP3K1; MAPKKK1; MEKK; MEKK1; MEKK1/MAP3K1 | KINOMEscan | Wild Type; Partial length | |||
| 200236 | MAP3K15 | 200236 | Q6ZN16 | Mitogen-activated protein kinase kinase kinase 15; bA723P2.3; FLJ16518; MAP3K15; MAP3K7 | KINOMEscan | Wild Type; Partial length | |||
| 200237 | M3K2 | 200237 | Q9Y2U5 | Mitogen-activated protein kinase kinase kinase 2; MAP3K2; MEKK2; MEKK2/MAP3K2; MEKK2B | KINOMEscan | Wild Type; Partial length | |||
| 200238 | MAP3K3 | 200238 | Q99759 | Mitogen-activated protein kinase kinase kinase 3; MAP3K3; MAPKKK3; MEKK3; MEKK3/MAP3K3 | KINOMEscan | Wild Type; Partial length |