Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| GSK923295 | HCC1419 | -4.4776 | 0.7713 | -4.3252 | -4.4776 | -5.8224 | 0.4978 | 0.0000 | 0.5992 | 8.0203 |
| GSK923295 | HCC1428 | -4.4776 | 0.8485 | -4.7519 | -4.7519 | -5.4242 | 1.0494 | 0.0000 | 0.3509 | 7.7604 |
| GSK923295 | HCC1569 | -4.4776 | 0.8841 | -6.9376 | -5.0060 | -6.6969 | 1.1643 | 0.4889 | 0.5046 | 6.9724 |
| GSK923295 | HCC1806 | -4.4776 | 0.9576 | -7.3626 | -7.2320 | -7.3834 | 2.1860 | 0.2401 | 0.2401 | 5.3896 |
| GSK923295 | HCC1937 | -4.4776 | 0.9405 | -7.4326 | -5.6934 | -7.3592 | 1.8280 | 0.5438 | 0.5438 | 6.8925 |
| GSK923295 | HCC1954 | -4.4776 | 0.9367 | -7.6491 | -7.5936 | -7.7045 | 2.7265 | 0.1315 | 0.1315 | 4.6766 |
| GSK923295 | HCC202 | -4.4776 | 0.8563 | -6.1138 | -5.6744 | -7.9337 | 0.5921 | 0.2096 | 0.4360 | 6.6078 |
| GSK923295 | HCC38 | -4.4776 | 0.9577 | -7.2931 | -7.1700 | -7.3851 | 2.6455 | 0.2601 | 0.2601 | 5.6362 |
| GSK923295 | HCC70 | -4.4776 | 0.9633 | -7.5556 | -7.4313 | -7.6963 | 3.4200 | 0.2869 | 0.2869 | 5.6469 |
| GSK923295 | Hs 578T | -4.4776 | 0.9347 | -7.3606 | -7.2775 | -7.3901 | 3.9990 | 0.2682 | 0.2682 | 5.6408 |
| GSK923295 | MB 157 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| GSK923295 | MDA-MB-134-VI | -4.4776 | 0.9558 | -6.9366 | -6.6702 | -6.9826 | 3.9770 | 0.4617 | 0.4617 | 7.7426 |
| GSK923295 | MDA-MB-157 | -4.4776 | 0.9609 | -7.5316 | -7.3921 | -7.5478 | 2.1110 | 0.2465 | 0.2465 | 5.3395 |
| GSK923295 | MDA-MB-175-VII | -4.4776 | 0.7133 | -7.2926 | -4.4776 | -7.1871 | 1.7850 | 0.7071 | 0.7071 | 7.7044 |
| GSK923295 | MDA-MB-361 | -4.4776 | 0.9721 | -7.4766 | -7.2310 | -7.5457 | 3.9980 | 0.4445 | 0.4445 | 6.2374 |
| GSK923295 | MDA-MB-436 | -4.4776 | 0.7796 | -7.7146 | -6.8133 | -7.6733 | 2.0440 | 0.4928 | 0.4928 | 6.4428 |
| GSK923295 | MDA-MB-453 | -4.4776 | 0.8328 | -7.2221 | -5.7582 | -7.2170 | 3.9990 | 0.5189 | 0.5189 | 7.0083 |
| GSK923295 | MDA-MB-468 | -4.4776 | 0.8812 | -7.7266 | -7.6512 | -7.8595 | 1.7550 | 0.1626 | 0.1626 | 4.6745 |
| GSK923295 | T47D | -4.4776 | 0.8357 | -7.2546 | -4.4776 | -7.3114 | 3.9880 | 0.5936 | 0.5936 | 7.2321 |
| GSK923295 | UACC-812 | -4.4776 | 0.8565 | -7.7516 | -4.4776 | -7.7834 | 3.9960 | 0.5864 | 0.5864 | 7.1470 |
| GSK923295 | UACC-893 | -4.4776 | 0.7353 | -7.4576 | -5.6887 | -7.5478 | 3.2150 | 0.4906 | 0.4906 | 6.6240 |
| GSK923295 | ZR-75-1 | -4.4776 | 0.9285 | -7.2206 | -4.4776 | -7.1424 | 3.9570 | 0.6168 | 0.6168 | 7.2322 |
| GSK923295 | 184B5 | -4.4776 | 0.7603 | -4.9213 | -4.9213 | -5.6113 | 1.2381 | 0.0000 | 0.2486 | 7.3003 |
| GSK923295 | HCC1187 | -4.4776 | 0.9843 | -7.4796 | -7.4551 | -7.6694 | 3.9940 | 0.0876 | 0.0876 | 4.5239 |
| GSK923295 | MCF 10A | -4.4776 | 0.9412 | -7.4031 | -7.1898 | -7.3207 | 3.0580 | 0.3669 | 0.3669 | 5.9720 |