Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Epirubicin | LY2 | -3.7645 | 0.8372 | -6.4390 | -6.4202 | -6.5226 | 2.1439 | 0.0728 | 0.1462 | 4.9061 |
| Epirubicin | ZR75B | -3.7645 | 0.9804 | -6.6145 | -6.5195 | -6.9691 | 0.9953 | 0.0980 | 0.0993 | 4.8835 |
| Etoposide | MCF7 | -3.4776 | 0.9319 | -4.6461 | -4.2247 | -5.1533 | 0.5006 | 0.1684 | 0.3706 | 7.1186 |
| Etoposide | SK-BR-3 | -3.4776 | 0.9864 | -5.7416 | -5.6804 | -5.9393 | 1.0745 | 0.0708 | 0.0743 | 5.6019 |
| Etoposide | MDA-MB-231 | -3.4776 | 0.9125 | -5.5001 | -5.4973 | -5.5939 | 1.2410 | 0.0230 | 0.0245 | 6.0232 |
| Etoposide | AU565 | -3.4776 | 0.9894 | -6.1256 | -6.1010 | -6.2330 | 1.6625 | 0.0437 | 0.0438 | 4.9192 |
| Etoposide | BT-20 | -3.4776 | 0.9749 | -5.2386 | -5.1292 | -5.5056 | 1.3330 | 0.1428 | 0.1466 | 6.4287 |
| Etoposide | BT-474 | -3.4776 | 0.9108 | -4.4573 | -3.9125 | -4.6587 | 1.1760 | 0.3856 | 0.4260 | 7.5962 |
| Etoposide | BT-483 | -3.4776 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 7.7183 |
| Etoposide | BT-549 | -3.4776 | 0.9693 | -5.8331 | -5.8288 | -5.9266 | 1.0780 | 0.0054 | 0.0083 | 5.3185 |
| Etoposide | CAMA-1 | -3.4776 | 0.9467 | -5.0031 | -4.7789 | -5.4490 | 1.0133 | 0.1952 | 0.2616 | 6.6985 |
| Etoposide | HCC1143 | -3.4776 | 0.9817 | -5.0596 | -4.9701 | -5.3093 | 0.8765 | 0.0830 | 0.1191 | 6.5680 |
| Etoposide | HCC1395 | -3.4776 | 0.9592 | -4.9076 | -4.6117 | -5.5596 | 0.5621 | 0.1566 | 0.2720 | 6.7302 |
| Etoposide | HCC1419 | -3.4776 | 0.8040 | -4.0378 | -3.4776 | -4.0615 | 4.0000 | 0.7433 | 0.7448 | 8.6123 |
| Etoposide | HCC1428 | -3.4776 | 0.9511 | -4.2405 | -3.9171 | -4.5105 | 1.1975 | 0.3122 | 0.3783 | 7.8407 |
| Etoposide | HCC1569 | -3.4776 | 0.9371 | -3.9339 | -3.9211 | -4.1879 | 0.6049 | 0.0000 | 0.3463 | 7.4779 |
| Etoposide | HCC1806 | -3.4776 | 0.8961 | -5.5486 | -5.4980 | -5.6338 | 2.4720 | 0.1129 | 0.1185 | 5.9521 |
| Etoposide | HCC1937 | -3.4776 | 0.9743 | -5.2096 | -5.0456 | -5.3767 | 1.0925 | 0.1688 | 0.1793 | 6.6741 |
| Etoposide | HCC1954 | -3.4776 | 0.9477 | -5.7446 | -5.7342 | -6.1019 | 0.7475 | 0.0099 | 0.0325 | 5.1728 |
| Etoposide | HCC202 | -3.4776 | 0.8996 | -5.4976 | -4.9024 | -6.0146 | 1.1340 | 0.3943 | 0.3974 | 7.0279 |
| Etoposide | HCC38 | -3.4776 | 0.9946 | -6.3751 | -6.3508 | -6.5517 | 1.4425 | 0.0394 | 0.0396 | 4.5558 |
| Etoposide | HCC70 | -3.4776 | 0.9232 | -4.5496 | -4.5492 | -5.3123 | 0.8621 | 0.0000 | 0.1065 | 6.5664 |
| Etoposide | Hs 578T | -3.4776 | 0.8892 | -5.2076 | -5.2046 | -5.2648 | 2.5125 | 0.0095 | 0.0096 | 7.0292 |
| Etoposide | MB 157 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Etoposide | MDA-MB-134-VI | -3.4776 | 0.9497 | -4.8486 | -4.0551 | -5.6362 | 0.5406 | 0.3137 | 0.4192 | 7.2305 |