Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Bortezomib | MDA-MB-361 | -3.7773 | 0.8601 | -4.3489 | -3.8887 | -4.8480 | 0.6586 | 0.3148 | 0.5610 | 8.4566 |
| Bortezomib | MDA-MB-436 | -3.7773 | 0.9927 | -6.7283 | -6.7046 | -6.8773 | 1.6020 | 0.0428 | 0.0428 | 4.4744 |
| Bortezomib | MDA-MB-453 | -3.7773 | 0.9763 | -7.2088 | -7.1412 | -7.4057 | 1.3085 | 0.0903 | 0.0905 | 4.0019 |
| Bortezomib | MDA-MB-468 | -3.7773 | 0.9712 | -7.0783 | -7.0761 | -7.1476 | 3.2220 | 0.0066 | 0.0066 | 3.7763 |
| Bortezomib | T47D | -3.7773 | 0.9910 | -7.3053 | -7.3057 | -7.4319 | 3.2440 | 0.0000 | 0.0000 | 3.3783 |
| Bortezomib | UACC-812 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Bortezomib | UACC-893 | -3.7773 | 0.9624 | -6.5223 | -6.3874 | -6.9889 | 0.9537 | 0.1282 | 0.1303 | 5.2383 |
| Bortezomib | ZR-75-1 | -3.7773 | 0.9683 | -6.5553 | -6.3845 | -6.9098 | 1.1429 | 0.1792 | 0.1806 | 5.3902 |
| Bortezomib | 184B5 | -3.7773 | 0.9844 | -7.5418 | -7.4975 | -7.7046 | 2.0090 | 0.0924 | 0.0924 | 3.6326 |
| Bortezomib | HCC1187 | -3.7773 | 0.9896 | -7.6223 | -7.6220 | -7.8008 | 3.0070 | 0.0000 | 0.0000 | 3.0973 |
| Bortezomib | MCF 10A | -3.7773 | 0.9309 | -5.9583 | -5.9251 | -6.0072 | 1.0860 | 0.0216 | 0.0457 | 5.7542 |
| Bortezomib | MCF 10F | -3.7773 | 0.9879 | -6.4513 | -6.4518 | -6.9070 | 0.7522 | 0.0000 | 0.0096 | 4.6275 |
| Bortezomib | SUM1315MO2 | -3.7773 | 0.9821 | -6.5778 | -6.5692 | -7.0549 | 1.1903 | 0.0142 | 0.0178 | 4.6391 |
| Bortezomib | SUM149PT | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Bortezomib | SUM159PT | -3.7773 | 0.9754 | -7.3913 | -7.3915 | -7.4495 | 1.5190 | 0.0000 | 0.0000 | 3.3800 |
| Bortezomib | SUM185PE | -3.7773 | 0.9489 | -6.9133 | -6.7805 | -7.5287 | 0.8378 | 0.1130 | 0.1151 | 4.7482 |
| Bortezomib | SUM225CWN | -3.7773 | 0.9664 | -7.0403 | -6.8934 | -7.3160 | 1.2120 | 0.1681 | 0.1682 | 4.8162 |
| Bortezomib | SUM229PE | -3.7773 | 0.9717 | -6.5023 | -6.4994 | -6.8705 | 1.5826 | 0.0082 | 0.0342 | 4.4892 |
| Bortezomib | SUM52PE | -3.7773 | 0.9864 | -7.5283 | -7.4785 | -7.6147 | 3.0630 | 0.1481 | 0.1481 | 4.0514 |
| Bortezomib | 184A1 | -3.7773 | 0.9426 | -7.1453 | -7.0276 | -7.5883 | 0.7653 | 0.0933 | 0.0972 | 4.3399 |
| Bortezomib | MCF12A | -3.7773 | 0.9807 | -6.5428 | -6.5421 | -6.7380 | 0.8571 | 0.0006 | 0.0197 | 4.4931 |
| Bortezomib | MX1 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Bortezomib | T47DKBLUC | -3.7773 | 0.9658 | -5.3463 | -5.3452 | -5.8237 | 1.1390 | 0.0007 | 0.0168 | 6.4181 |
| Bortezomib | 600MPE | -3.7773 | 0.9869 | -5.7338 | -5.7172 | -6.2270 | 1.4452 | 0.0209 | 0.0691 | 5.6730 |
| Bortezomib | HCC2185 | -3.7773 | 0.9688 | -7.2453 | -7.0811 | -7.7137 | 1.5240 | 0.2088 | 0.2088 | 4.8324 |