Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| 5-FU | AU565 | -1.7167 | 0.9613 | -4.4707 | -4.0266 | -5.2077 | 0.7024 | 0.1849 | 0.2294 | 5.7445 |
| 5-FU | BT-20 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| 5-FU | BT-474 | -1.7167 | 0.9589 | -2.9757 | -2.7833 | -3.7369 | 0.7497 | 0.1304 | 0.2255 | 7.0657 |
| 5-FU | BT-483 | -1.7167 | 0.9825 | -3.1657 | -2.8988 | -4.4387 | 0.5142 | 0.1355 | 0.2673 | 6.7117 |
| 5-FU | BT-549 | -1.7167 | 0.9827 | -4.0937 | -3.7517 | -4.0766 | 0.6478 | 0.1526 | 0.2076 | 5.9703 |
| 5-FU | CAMA-1 | -1.7167 | 0.8554 | -2.8017 | -2.6620 | -3.6658 | 0.5456 | 0.0805 | 0.2678 | 6.8685 |
| 5-FU | HCC1143 | -1.7167 | 0.8869 | -3.6887 | -2.7043 | -4.0603 | 0.6150 | 0.3760 | 0.4120 | 6.9066 |
| 5-FU | HCC1395 | -1.7167 | 0.9443 | -2.7133 | -2.4761 | -3.4506 | 0.6306 | 0.1958 | 0.3078 | 7.7165 |
| 5-FU | HCC1419 | -1.7167 | 0.9665 | -3.0147 | -2.8298 | -3.6970 | 1.0720 | 0.2720 | 0.2886 | 7.1156 |
| 5-FU | HCC1428 | -1.7167 | 0.9024 | -4.7157 | -4.5358 | -5.1729 | 0.9946 | 0.1689 | 0.1698 | 4.6703 |
| 5-FU | HCC1569 | -1.7167 | 0.9690 | -3.5487 | -3.4078 | -3.9617 | 0.4822 | 0.0701 | 0.1552 | 6.1255 |
| 5-FU | HCC1806 | -1.7167 | 0.9440 | -4.0882 | -4.0549 | -4.6127 | 0.4590 | 0.0168 | 0.0943 | 5.1471 |
| 5-FU | HCC1937 | -1.7167 | 0.9840 | -3.5447 | -3.0727 | -3.8045 | 0.5859 | 0.2356 | 0.2954 | 6.6167 |
| 5-FU | HCC1954 | -1.7167 | 0.9470 | -4.3322 | -4.1860 | -4.8025 | 0.6321 | 0.0969 | 0.1229 | 5.1632 |
| 5-FU | HCC202 | -1.7167 | 0.9417 | -2.9592 | -2.8154 | -4.7867 | 0.6491 | 0.1120 | 0.2636 | 6.8495 |
| 5-FU | HCC38 | -1.7167 | 0.9252 | -3.2057 | -3.0867 | -3.7252 | 0.6600 | 0.0829 | 0.1695 | 6.6686 |
| 5-FU | HCC70 | -1.7167 | 0.9771 | -3.8037 | -3.7894 | -4.1996 | 1.6670 | 0.0057 | 0.0132 | 5.5719 |
| 5-FU | Hs 578T | -1.7167 | 0.9632 | -4.0727 | -4.0161 | -4.3797 | 0.7356 | 0.0461 | 0.0955 | 5.3493 |
| 5-FU | MB 157 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| 5-FU | MDA-MB-134-VI | -1.7167 | 0.9445 | -2.9097 | -2.5858 | -3.5621 | 0.8234 | 0.2297 | 0.3023 | 8.2612 |
| 5-FU | MDA-MB-157 | -1.7167 | 0.9802 | -3.0647 | -2.6788 | -3.1374 | 0.7550 | 0.2443 | 0.3105 | 7.2573 |
| 5-FU | MDA-MB-175-VII | -1.7167 | 0.9818 | -3.0992 | -3.0736 | -3.9453 | 0.7820 | 0.0244 | 0.1021 | 6.5766 |
| 5-FU | MDA-MB-361 | -1.7167 | 0.9833 | -3.1737 | -3.1738 | -3.9518 | 0.7705 | 0.0000 | 0.0702 | 6.4145 |
| 5-FU | MDA-MB-436 | -1.7167 | 0.7179 | -2.7477 | -2.4610 | -3.3629 | 0.5233 | 0.1459 | 0.3373 | 7.2900 |
| 5-FU | MDA-MB-453 | -1.7167 | 0.9622 | -2.9422 | -2.9301 | -3.9984 | 0.4001 | 0.0060 | 0.2491 | 6.4576 |