Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| 5-DFUR | UACC-893 | -2.3010 | 0.8073 | -2.0053 | -2.3010 | -4.0077 | 0.3772 | 0.0000 | 0.5639 | 7.7344 |
| 5-DFUR | ZR-75-1 | -2.3010 | 0.8335 | -5.2335 | -3.0525 | -5.3717 | 0.3718 | 0.4176 | 0.4622 | 6.2786 |
| 5-DFUR | 184B5 | -2.3010 | 0.8541 | -2.7726 | -2.7726 | -3.6487 | 0.3219 | 0.0000 | 0.4135 | 7.0046 |
| 5-DFUR | HCC1187 | -2.3010 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 6.5607 |
| 5-DFUR | MCF 10A | -2.3010 | 0.9599 | -4.8340 | -4.7882 | -4.8935 | 1.2080 | 0.0596 | 0.0604 | 5.2312 |
| 5-DFUR | MCF 10F | -2.3010 | 0.9449 | -3.6930 | -3.3982 | -4.3437 | 0.4010 | 0.1192 | 0.3100 | 6.6381 |
| 5-DFUR | SUM1315MO2 | -2.3010 | 0.8765 | -2.7637 | -2.3010 | -3.1805 | 0.8983 | 0.3580 | 0.5408 | 8.2873 |
| 5-DFUR | SUM149PT | -2.3010 | 0.9442 | -3.9790 | -3.8778 | -4.1766 | 0.6444 | 0.0696 | 0.1409 | 6.1461 |
| 5-DFUR | SUM159PT | -2.3010 | 0.9698 | -4.5540 | -4.4826 | -4.5480 | 0.8020 | 0.0619 | 0.0763 | 5.3764 |
| 5-DFUR | SUM185PE | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| 5-DFUR | SUM225CWN | -2.3010 | 0.8231 | -2.8782 | -2.7022 | -3.5439 | 0.7391 | 0.1331 | 0.3795 | 7.6664 |
| 5-DFUR | SUM229PE | -2.3010 | 0.8967 | -3.8490 | -3.8491 | -4.1867 | 0.3898 | 0.0000 | 0.1995 | 5.8891 |
| 5-DFUR | SUM52PE | -2.3010 | 0.9222 | -3.1384 | -2.9055 | -3.4754 | 0.8098 | 0.1765 | 0.3279 | 7.5784 |
| 5-DFUR | 184A1 | -2.3010 | 0.9310 | -2.9819 | -2.9819 | -3.6467 | 0.5276 | 0.0000 | 0.3042 | 7.3885 |
| 5-DFUR | MCF12A | -2.3010 | 0.9769 | -4.4605 | -4.4604 | -4.8749 | 0.5344 | 0.0000 | 0.0680 | 5.3277 |
| 5-DFUR | MX1 | -2.3010 | 0.8188 | -2.3676 | -2.3675 | -2.9598 | 1.0810 | 0.0000 | 0.4587 | 7.4046 |
| 5-DFUR | T47DKBLUC | -2.3010 | 0.7959 | -2.1199 | -2.3010 | -2.8097 | 0.5814 | 0.0000 | 0.5604 | 8.0350 |
| 5-DFUR | 600MPE | -2.3010 | 0.8708 | -5.5840 | -2.8235 | -5.9297 | 0.4375 | 0.4690 | 0.4878 | 6.3142 |
| 5-DFUR | HCC2185 | -2.3010 | 0.8231 | -1.9221 | -2.3010 | -3.8435 | 0.5251 | 0.0000 | 0.6126 | 8.3218 |
| 5-DFUR | HCC3153 | -2.3010 | 0.8983 | -2.7583 | -2.4788 | -3.1023 | 0.9076 | 0.2168 | 0.4512 | 7.8074 |
| 5-DFUR | LY2 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| 5-DFUR | ZR75B | -2.3010 | 0.9182 | -5.2980 | -4.6168 | -5.2073 | 0.7728 | 0.3511 | 0.3542 | 5.8877 |
| 5-FU | MCF7 | -1.7167 | 0.9467 | -3.7182 | -3.5542 | -4.3345 | 0.5254 | 0.0859 | 0.1618 | 5.9745 |
| 5-FU | SK-BR-3 | -1.7167 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 6.1999 |
| 5-FU | MDA-MB-231 | -1.7167 | 0.9359 | -3.5862 | -3.4067 | -3.7244 | 0.8247 | 0.1092 | 0.1520 | 6.1609 |