Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Lestaurtinib | HCC1806 | -4.4776 | 0.9867 | -6.7396 | -6.7272 | -6.8390 | 1.7540 | 0.0254 | 0.0255 | 5.2897 |
| Lestaurtinib | HCC1937 | -4.4776 | 0.9206 | -5.7456 | -5.7459 | -6.2057 | 0.8884 | 0.0000 | 0.0695 | 6.7655 |
| Lestaurtinib | HCC1954 | -4.4776 | 0.9359 | -5.2449 | -5.2448 | -5.3917 | 1.9150 | 0.0000 | 0.0328 | 7.0970 |
| Lestaurtinib | HCC202 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Lestaurtinib | HCC38 | -4.4776 | 0.9876 | -7.1366 | -7.1218 | -7.2491 | 1.9080 | 0.0305 | 0.0305 | 4.7421 |
| Lestaurtinib | HCC70 | -4.4776 | 0.9573 | -6.2706 | -6.2395 | -6.7110 | 0.9077 | 0.0350 | 0.0685 | 6.0920 |
| Lestaurtinib | Hs 578T | -4.4776 | 0.9723 | -5.8196 | -5.8201 | -6.0004 | 0.9173 | 0.0000 | 0.0554 | 6.6494 |
| Lestaurtinib | MB 157 | -4.4776 | 0.9869 | -5.8896 | -5.8833 | -6.0548 | 1.1310 | 0.0086 | 0.0331 | 6.5560 |
| Lestaurtinib | MDA-MB-134-VI | -4.4776 | 0.9433 | -5.5687 | -5.5685 | -6.4747 | 0.5912 | 0.0000 | 0.1881 | 6.7286 |
| Lestaurtinib | MDA-MB-157 | -4.4776 | 0.9434 | -6.2476 | -6.1515 | -6.4829 | 1.1360 | 0.1115 | 0.1201 | 6.4404 |
| Lestaurtinib | MDA-MB-175-VII | -4.4776 | 0.7465 | -6.0516 | -5.1586 | -6.3133 | 2.4785 | 0.4079 | 0.4115 | 7.0386 |
| Lestaurtinib | MDA-MB-361 | -4.4776 | 0.9520 | -5.7011 | -5.7009 | -6.3335 | 1.1589 | 0.0000 | 0.0548 | 6.8121 |
| Lestaurtinib | MDA-MB-436 | -4.4776 | 0.9325 | -5.6516 | -5.5581 | -5.9136 | 1.2990 | 0.1215 | 0.1470 | 7.2830 |
| Lestaurtinib | MDA-MB-453 | -4.4776 | 0.9758 | -5.8596 | -5.8463 | -6.2015 | 1.1420 | 0.0175 | 0.0428 | 6.6264 |
| Lestaurtinib | MDA-MB-468 | -4.4776 | 0.9369 | -6.1616 | -6.1614 | -6.4138 | 0.6748 | 0.0000 | 0.0681 | 5.9735 |
| Lestaurtinib | T47D | -4.4776 | 0.9420 | -5.1838 | -5.1117 | -5.2759 | 1.9240 | 0.1366 | 0.1728 | 7.5982 |
| Lestaurtinib | UACC-812 | -4.4776 | 0.9075 | -5.5307 | -5.5307 | -6.1955 | 0.9419 | 0.0000 | 0.0945 | 6.7829 |
| Lestaurtinib | UACC-893 | -4.4776 | 0.9446 | -5.3436 | -5.3437 | -5.7235 | 2.2240 | 0.0000 | 0.0117 | 7.4229 |
| Lestaurtinib | ZR-75-1 | -4.4776 | 0.8071 | -4.9951 | -4.9951 | -5.8634 | 0.5333 | 0.0000 | 0.3460 | 7.1442 |
| Lestaurtinib | 184B5 | -4.4776 | 0.9783 | -6.2066 | -6.2065 | -6.5206 | 0.9772 | 0.0000 | 0.0200 | 5.8920 |
| Lestaurtinib | HCC1187 | -4.4776 | 0.8869 | -5.6306 | -5.6305 | -6.0003 | 0.6822 | 0.0000 | 0.1405 | 6.9718 |
| Lestaurtinib | MCF 10A | -4.4776 | 0.9399 | -6.2046 | -6.2048 | -6.3193 | 0.6804 | 0.0000 | 0.0626 | 5.7908 |
| Lestaurtinib | MCF 10F | -4.4776 | 0.9504 | -5.5926 | -5.5832 | -5.7297 | 2.0180 | 0.0215 | 0.0270 | 7.2322 |
| Lestaurtinib | SUM1315MO2 | -4.4776 | 0.9683 | -6.5221 | -6.4887 | -7.3929 | 0.6128 | 0.0254 | 0.0834 | 5.6607 |
| Lestaurtinib | SUM149PT | -4.4776 | 0.9550 | -6.8931 | -6.8846 | -7.1684 | 0.6260 | 0.0073 | 0.0415 | 5.0130 |