Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Sunitinib | MDA-MB-436 | -3.7773 | 0.9707 | -5.3423 | -5.3419 | -5.4884 | 1.3390 | 0.0000 | 0.0080 | 6.0490 |
| Sunitinib | MDA-MB-453 | -3.7773 | 0.7115 | -5.2463 | -5.1553 | -5.3328 | 2.3890 | 0.1964 | 0.1967 | 6.8202 |
| Sunitinib | MDA-MB-468 | -3.7773 | 0.9604 | -5.2273 | -5.2275 | -5.4078 | 1.2605 | 0.0000 | 0.0155 | 6.2161 |
| Sunitinib | T47D | -3.7773 | 0.9814 | -4.8833 | -4.8830 | -4.9736 | 3.9960 | 0.0000 | 0.0000 | 7.1754 |
| Sunitinib | UACC-812 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Sunitinib | UACC-893 | -3.7773 | 0.7020 | -4.9393 | -4.8858 | -5.0728 | 3.9840 | 0.1943 | 0.1943 | 7.5005 |
| Sunitinib | ZR-75-1 | -3.7773 | 0.9837 | -4.8408 | -4.8407 | -4.9558 | 3.8465 | 0.0000 | 0.0001 | 7.0373 |
| Sunitinib | 184B5 | -3.7773 | 0.9902 | -5.1233 | -5.1228 | -5.2864 | 2.5950 | 0.0021 | 0.0045 | 6.6070 |
| Sunitinib | HCC1187 | -3.7773 | 0.9785 | -5.1068 | -5.1071 | -5.2545 | 3.3595 | 0.0000 | 0.0001 | 6.7382 |
| Sunitinib | MCF 10A | -3.7773 | 0.9650 | -5.2223 | -5.2222 | -5.3010 | 1.7760 | 0.0000 | 0.0024 | 6.1671 |
| Sunitinib | MCF 10F | -3.7773 | 0.9685 | -5.2723 | -5.2671 | -5.3932 | 2.8860 | 0.0177 | 0.0178 | 6.5541 |
| Sunitinib | SUM1315MO2 | -3.7773 | 0.9914 | -5.0033 | -5.0029 | -5.1409 | 3.6140 | 0.0000 | 0.0000 | 6.7848 |
| Sunitinib | SUM149PT | -3.7773 | 0.9739 | -5.4943 | -5.4940 | -5.6171 | 1.6930 | 0.0000 | 0.0012 | 6.0576 |
| Sunitinib | SUM159PT | -3.7773 | 0.9527 | -5.8123 | -5.8125 | -5.8594 | 1.4710 | 0.0000 | 0.0010 | 5.2877 |
| Sunitinib | SUM185PE | -3.7773 | 0.9616 | -5.4933 | -5.4929 | -6.0636 | 0.9412 | 0.0000 | 0.0237 | 5.6919 |
| Sunitinib | SUM225CWN | -3.7773 | 0.9767 | -5.0768 | -5.0769 | -5.2252 | 3.1835 | 0.0000 | 0.0001 | 6.7349 |
| Sunitinib | SUM229PE | -3.7773 | 0.9788 | -5.3173 | -5.3169 | -5.5009 | 1.2770 | 0.0000 | 0.0107 | 6.0188 |
| Sunitinib | SUM52PE | -3.7773 | 0.9788 | -5.6913 | -5.6909 | -5.9821 | 1.1640 | 0.0000 | 0.0059 | 5.4960 |
| Sunitinib | 184A1 | -3.7773 | 0.9722 | -5.2038 | -5.2018 | -5.3508 | 2.4980 | 0.0078 | 0.0101 | 6.7274 |
| Sunitinib | MCF12A | -3.7773 | 0.9671 | -5.1293 | -5.1288 | -5.1979 | 3.0015 | 0.0015 | 0.0024 | 6.7915 |
| Sunitinib | MX1 | -3.7773 | 0.9657 | -5.0223 | -5.0223 | -5.2285 | 2.7100 | 0.0000 | 0.0004 | 6.3318 |
| Sunitinib | T47DKBLUC | -3.7773 | 0.9780 | -4.9393 | -4.9395 | -5.0752 | 4.0000 | 0.0014 | 0.0014 | 6.9655 |
| Sunitinib | 600MPE | -3.7773 | 0.9440 | -5.1878 | -5.1875 | -5.4358 | 2.6935 | 0.0032 | 0.0056 | 6.2428 |
| Sunitinib | HCC2185 | -3.7773 | 0.9682 | -4.7913 | -4.7911 | -4.9707 | 2.5710 | 0.0000 | 0.0025 | 7.1741 |
| Sunitinib | HCC3153 | -3.7773 | 0.9888 | -4.9143 | -4.9136 | -5.0281 | 3.8275 | 0.0030 | 0.0031 | 6.9172 |