Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Sunitinib | SK-BR-3 | -3.7773 | 0.9750 | -5.0748 | -5.0748 | -5.1762 | 2.4590 | 0.0000 | 0.0007 | 6.4568 |
| Sunitinib | MDA-MB-231 | -3.7773 | 0.9510 | -5.3458 | -5.3460 | -5.4018 | 2.7870 | 0.0000 | 0.0008 | 6.3279 |
| Sunitinib | AU565 | -3.7773 | 0.9773 | -5.3158 | -5.3157 | -5.4531 | 1.4640 | 0.0000 | 0.0058 | 6.2895 |
| Sunitinib | BT-20 | -3.7773 | 0.9703 | -4.8163 | -4.8163 | -4.9181 | 3.9950 | 0.0000 | 0.0001 | 7.0490 |
| Sunitinib | BT-474 | -3.7773 | 0.9747 | -4.8004 | -4.8006 | -4.9414 | 3.9815 | 0.0000 | 0.0001 | 7.2094 |
| Sunitinib | BT-483 | -3.7773 | 0.9482 | -4.8363 | -4.8355 | -5.0244 | 3.9990 | 0.0049 | 0.0049 | 6.5248 |
| Sunitinib | BT-549 | -3.7773 | 0.9542 | -5.2298 | -5.2301 | -5.2835 | 2.1910 | 0.0000 | 0.0017 | 6.7587 |
| Sunitinib | CAMA-1 | -3.7773 | 0.9798 | -4.9863 | -4.9856 | -5.0970 | 4.0000 | 0.0030 | 0.0031 | 6.6815 |
| Sunitinib | HCC1143 | -3.7773 | 0.9790 | -5.0783 | -5.0756 | -5.1346 | 4.0000 | 0.0126 | 0.0126 | 6.9305 |
| Sunitinib | HCC1395 | -3.7773 | 0.8577 | -5.1438 | -5.1190 | -5.2641 | 3.5555 | 0.0908 | 0.0908 | 6.7614 |
| Sunitinib | HCC1419 | -3.7773 | 0.8508 | -4.8313 | -4.7988 | -5.0314 | 3.9970 | 0.1123 | 0.1123 | 7.4474 |
| Sunitinib | HCC1428 | -3.7773 | 0.9792 | -5.0478 | -5.0479 | -5.2565 | 2.5880 | 0.0000 | 0.0006 | 6.4400 |
| Sunitinib | HCC1569 | -3.7773 | 0.9785 | -5.0693 | -5.0677 | -5.1025 | 3.5100 | 0.0059 | 0.0059 | 6.7454 |
| Sunitinib | HCC1806 | -3.7773 | 0.9660 | -5.2428 | -5.2423 | -5.3269 | 2.8690 | 0.0014 | 0.0022 | 6.6067 |
| Sunitinib | HCC1937 | -3.7773 | 0.9900 | -5.1233 | -5.1220 | -5.1909 | 3.9990 | 0.0073 | 0.0073 | 7.1586 |
| Sunitinib | HCC1954 | -3.7773 | 0.8580 | -5.2013 | -5.1552 | -5.2709 | 2.3805 | 0.0964 | 0.0968 | 6.5831 |
| Sunitinib | HCC202 | -3.7773 | 0.9672 | -4.8723 | -4.8721 | -5.0692 | 3.4510 | 0.0000 | 0.0002 | 7.0261 |
| Sunitinib | HCC38 | -3.7773 | 0.9828 | -5.2658 | -5.2654 | -5.3474 | 3.3930 | 0.0016 | 0.0016 | 6.2730 |
| Sunitinib | HCC70 | -3.7773 | 0.9709 | -5.2273 | -5.2269 | -5.6217 | 1.1930 | 0.0000 | 0.0183 | 6.3482 |
| Sunitinib | Hs 578T | -3.7773 | 0.8796 | -5.3033 | -5.3035 | -5.4180 | 1.6020 | 0.0000 | 0.0025 | 6.2252 |
| Sunitinib | MB 157 | -3.7773 | 0.8627 | -5.4393 | -5.4390 | -5.6747 | 0.9393 | 0.0000 | 0.0268 | 5.6750 |
| Sunitinib | MDA-MB-134-VI | -3.7773 | 0.9658 | -4.9123 | -4.9109 | -5.0599 | 3.6070 | 0.0046 | 0.0047 | 6.6684 |
| Sunitinib | MDA-MB-157 | -3.7773 | 0.9732 | -5.1423 | -5.1219 | -5.2297 | 3.9920 | 0.0060 | 0.0060 | 6.5503 |
| Sunitinib | MDA-MB-175-VII | -3.7773 | 0.9650 | -5.0423 | -5.0426 | -5.2229 | 3.3880 | 0.0000 | 0.0001 | 6.4103 |
| Sunitinib | MDA-MB-361 | -3.7773 | 0.9747 | -4.8393 | -4.8396 | -4.9777 | 2.4310 | 0.0000 | 0.0026 | 7.0481 |