Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| GSK1059615 | BT-20 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| GSK1059615 | BT-474 | -3.8761 | 0.9798 | -6.2251 | -6.0257 | -6.7962 | 0.7758 | 0.1499 | 0.1625 | 5.7058 |
| GSK1059615 | BT-483 | -3.8761 | 0.9638 | -6.0801 | -5.6847 | -6.8353 | 0.7491 | 0.2470 | 0.2635 | 6.3311 |
| GSK1059615 | BT-549 | -3.8761 | 0.9806 | -5.6641 | -5.6536 | -5.7899 | 0.9404 | 0.0118 | 0.0306 | 5.8174 |
| GSK1059615 | CAMA-1 | -3.8761 | 0.9730 | -5.5201 | -5.3972 | -5.8029 | 1.1190 | 0.1362 | 0.1485 | 6.5521 |
| GSK1059615 | HCC1143 | -3.8761 | 0.9594 | -5.9431 | -5.8080 | -6.2536 | 1.2900 | 0.1654 | 0.1672 | 6.3813 |
| GSK1059615 | HCC1395 | -3.8761 | 0.9637 | -5.2131 | -5.1952 | -5.6662 | 1.0680 | 0.0583 | 0.0922 | 6.7219 |
| GSK1059615 | HCC1419 | -3.8761 | 0.9333 | -5.9671 | -5.7072 | -6.6644 | 1.4260 | 0.2758 | 0.2770 | 6.4366 |
| GSK1059615 | HCC1428 | -3.8761 | 0.9811 | -5.6961 | -5.6863 | -6.2551 | 1.0073 | 0.0109 | 0.0258 | 6.0014 |
| GSK1059615 | HCC1569 | -3.8761 | 0.9564 | -5.8856 | -5.7588 | -5.9550 | 1.8415 | 0.2056 | 0.2058 | 6.4466 |
| GSK1059615 | HCC1806 | -3.8761 | 0.9693 | -5.5871 | -5.5872 | -5.8567 | 0.7958 | 0.0000 | 0.0417 | 5.9921 |
| GSK1059615 | HCC1937 | -3.8761 | 0.9685 | -5.8166 | -5.6857 | -6.1338 | 1.0427 | 0.0914 | 0.1093 | 6.1835 |
| GSK1059615 | HCC1954 | -3.8761 | 0.9806 | -6.4821 | -6.4688 | -6.6416 | 1.7280 | 0.0209 | 0.0209 | 4.9360 |
| GSK1059615 | HCC202 | -3.8761 | 0.9640 | -6.5396 | -6.3348 | -7.0861 | 1.2425 | 0.2168 | 0.2172 | 5.4872 |
| GSK1059615 | HCC38 | -3.8761 | 0.9259 | -5.8441 | -5.7804 | -6.0941 | 1.6170 | 0.1049 | 0.1052 | 6.1396 |
| GSK1059615 | HCC70 | -3.8761 | 0.9860 | -6.1671 | -6.1571 | -6.7682 | 1.0470 | 0.0096 | 0.0180 | 5.3747 |
| GSK1059615 | Hs 578T | -3.8761 | 0.9639 | -5.5771 | -5.5431 | -5.7678 | 1.2410 | 0.0261 | 0.0406 | 6.2605 |
| GSK1059615 | MB 157 | -3.8761 | 0.9303 | -5.3471 | -5.1653 | -6.1416 | 0.9344 | 0.1621 | 0.1960 | 6.7770 |
| GSK1059615 | MDA-MB-134-VI | -3.8761 | 0.9728 | -5.7421 | -5.7232 | -6.2573 | 1.6810 | 0.0075 | 0.0147 | 5.8201 |
| GSK1059615 | MDA-MB-157 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| GSK1059615 | MDA-MB-175-VII | -3.8761 | 0.9661 | -5.7096 | -5.6435 | -6.2973 | 1.1415 | 0.0827 | 0.0908 | 6.0761 |
| GSK1059615 | MDA-MB-361 | -3.8761 | 0.9495 | -5.4711 | -5.3520 | -5.9326 | 0.9915 | 0.0984 | 0.1096 | 6.6257 |
| GSK1059615 | MDA-MB-436 | -3.8761 | 0.8235 | -6.1261 | -5.7066 | -6.5611 | 1.0757 | 0.2918 | 0.3127 | 6.4231 |
| GSK1059615 | MDA-MB-453 | -3.8761 | 0.9721 | -6.2611 | -6.1978 | -6.5344 | 1.4305 | 0.0940 | 0.0944 | 5.4412 |
| GSK1059615 | MDA-MB-468 | -3.8761 | 0.8850 | -6.0401 | -6.0191 | -6.1832 | 3.9980 | 0.0894 | 0.0894 | 6.0591 |