Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Taxol | HCC3153 | -4.4776 | 0.9571 | -7.7516 | -7.4172 | -7.7456 | 2.1960 | 0.4086 | 0.4086 | 5.9891 |
| Taxol | LY2 | -4.4776 | 0.9434 | -7.9566 | -7.7585 | -7.9800 | 3.3255 | 0.3542 | 0.3542 | 5.6728 |
| Taxol | ZR75B | -4.4776 | 0.8909 | -7.8031 | -4.4776 | -7.5531 | 1.3873 | 0.6042 | 0.6069 | 6.9605 |
| MG-132 | MCF7 | -4.1759 | 0.9513 | -6.2379 | -6.2360 | -6.4871 | 1.3880 | 0.0023 | 0.0037 | 5.3974 |
| MG-132 | MCF7 | -4.1759 | 0.9758 | -6.1479 | -6.1376 | -6.4133 | 1.1130 | 0.0129 | 0.0191 | 5.6668 |
| MG-132 | SK-BR-3 | -4.1759 | 0.8024 | -6.4469 | -6.3834 | -6.4834 | 3.8520 | 0.2166 | 0.2166 | 5.8826 |
| MG-132 | SK-BR-3 | -4.1759 | 0.9778 | -6.5509 | -6.5346 | -6.6594 | 2.6920 | 0.0484 | 0.0484 | 5.1822 |
| MG-132 | MDA-MB-231 | -4.1759 | 0.8435 | -6.6579 | -6.6324 | -6.6622 | 3.9980 | 0.1031 | 0.1031 | 5.3673 |
| MG-132 | MDA-MB-231 | -4.1759 | 0.9713 | -6.6199 | -6.6179 | -6.6688 | 2.4250 | 0.0067 | 0.0067 | 4.9246 |
| MG-132 | AU565 | -4.1759 | 0.9201 | -6.6274 | -6.6094 | -6.7017 | 3.6365 | 0.0712 | 0.0712 | 5.2001 |
| MG-132 | AU565 | -4.1759 | 0.9861 | -6.8929 | -6.8879 | -7.0390 | 2.1840 | 0.0128 | 0.0128 | 4.5793 |
| MG-132 | BT-20 | -4.1759 | 0.9741 | -6.2394 | -6.2225 | -6.3956 | 3.0190 | 0.0523 | 0.0524 | 5.5865 |
| MG-132 | BT-20 | -4.1759 | 0.8406 | -7.0069 | -6.9822 | -7.2724 | 2.7675 | 0.0756 | 0.0756 | 4.5551 |
| MG-132 | BT-474 | -4.1759 | 0.7572 | -6.2779 | -6.0532 | -6.3577 | 1.8970 | 0.3129 | 0.3130 | 6.5819 |
| MG-132 | BT-474 | -4.1759 | 0.9589 | -6.1479 | -6.0913 | -6.8734 | 0.9321 | 0.1025 | 0.1060 | 5.6441 |
| MG-132 | BT-483 | -4.1759 | 0.9522 | -5.9114 | -5.6002 | -6.7968 | 0.8636 | 0.2140 | 0.2528 | 6.5526 |
| MG-132 | BT-483 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| MG-132 | BT-549 | -4.1759 | 0.9898 | -7.0969 | -7.0952 | -7.1274 | 4.0000 | 0.0087 | 0.0087 | 4.2754 |
| MG-132 | BT-549 | -4.1759 | 0.8289 | -6.8509 | -6.8318 | -6.8836 | 3.9980 | 0.0804 | 0.0804 | 5.0112 |
| MG-132 | CAMA-1 | -4.1759 | 0.9825 | -6.6329 | -6.6194 | -6.7944 | 3.1845 | 0.0409 | 0.0409 | 4.9827 |
| MG-132 | CAMA-1 | -4.1759 | 0.8250 | -6.5769 | -6.5282 | -6.7204 | 3.1330 | 0.1484 | 0.1484 | 5.4384 |
| MG-132 | HCC1143 | -4.1759 | 0.7845 | -6.4689 | -6.3925 | -6.5354 | 2.2740 | 0.1650 | 0.1650 | 5.5468 |
| MG-132 | HCC1143 | -4.1759 | 0.9602 | -6.7579 | -6.7479 | -6.8664 | 2.0150 | 0.0235 | 0.0235 | 4.6141 |
| MG-132 | HCC1395 | -4.1759 | 0.9792 | -6.5089 | -6.4601 | -6.7262 | 2.2110 | 0.1097 | 0.1097 | 5.4200 |
| MG-132 | HCC1395 | -4.1759 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 6.1269 |