Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Taxol | MDA-MB-361 | -4.4776 | 0.9721 | -7.7206 | -7.0959 | -7.8297 | 1.4295 | 0.4323 | 0.4323 | 6.0960 |
| Taxol | MDA-MB-436 | -4.4776 | 0.8422 | -7.5231 | -6.9992 | -7.6578 | 2.1745 | 0.4139 | 0.4140 | 6.3324 |
| Taxol | MDA-MB-453 | -4.4776 | 0.9433 | -7.9441 | -7.7237 | -8.0207 | 2.8850 | 0.3800 | 0.3800 | 6.0301 |
| Taxol | MDA-MB-468 | -4.4776 | 0.9946 | -8.1086 | -8.0920 | -8.1719 | 3.9990 | 0.0721 | 0.0721 | 3.6461 |
| Taxol | T47D | -4.4776 | 0.9623 | -8.0116 | -6.0775 | -8.0746 | 3.9980 | 0.4890 | 0.4890 | 6.2255 |
| Taxol | UACC-812 | -4.4776 | 0.8730 | -8.0501 | -4.4776 | -8.1042 | 3.9930 | 0.6271 | 0.6271 | 6.9341 |
| Taxol | UACC-893 | -4.4776 | 0.8644 | -7.7571 | -6.0194 | -7.8858 | 3.3115 | 0.5061 | 0.5061 | 7.1464 |
| Taxol | ZR-75-1 | -4.4776 | 0.9309 | -7.9131 | -4.4776 | -7.7855 | 2.7500 | 0.7078 | 0.7078 | 7.4720 |
| Taxol | 184B5 | -4.4776 | 0.8674 | -7.9836 | -4.4776 | -7.8019 | 1.1050 | 0.5757 | 0.5758 | 6.7593 |
| Taxol | HCC1187 | -4.4776 | 0.9895 | -7.9666 | -7.9568 | -8.1326 | 3.9970 | 0.0756 | 0.0756 | 4.0268 |
| Taxol | MCF 10A | -4.4776 | 0.9866 | -8.0476 | -7.9773 | -8.0613 | 2.1785 | 0.1558 | 0.1558 | 4.2751 |
| Taxol | MCF 10F | -4.4776 | 0.9947 | -8.1156 | -7.9727 | -8.1102 | 2.0220 | 0.2428 | 0.2428 | 4.6787 |
| Taxol | SUM1315MO2 | -4.4776 | 0.9929 | -7.8166 | -7.5886 | -8.0292 | 1.5800 | 0.2818 | 0.2818 | 5.2763 |
| Taxol | SUM149PT | -4.4776 | 0.9614 | -8.1036 | -8.0475 | -8.1202 | 4.0000 | 0.2002 | 0.2002 | 4.7283 |
| Taxol | SUM159PT | -4.4776 | 0.9820 | -8.4646 | -8.4355 | -8.4836 | 2.2040 | 0.0682 | 0.0682 | 3.1856 |
| Taxol | SUM185PE | -4.4776 | 0.9568 | -7.6056 | -4.4776 | -7.6561 | 2.0200 | 0.5571 | 0.5571 | 7.2149 |
| Taxol | SUM225CWN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Taxol | SUM229PE | -4.4776 | 0.9844 | -7.7836 | -7.5710 | -7.7818 | 2.4190 | 0.3225 | 0.3225 | 5.5947 |
| Taxol | SUM52PE | -4.4776 | 0.9808 | -8.4026 | -7.9916 | -8.3327 | 2.0320 | 0.2643 | 0.2643 | 4.6139 |
| Taxol | 184A1 | -4.4776 | 0.8586 | -7.7586 | -4.4776 | -7.1300 | 1.5600 | 0.6613 | 0.6613 | 7.5136 |
| Taxol | MCF12A | -4.4776 | 0.9575 | -7.9916 | -7.8720 | -7.9736 | 3.9900 | 0.3105 | 0.3105 | 5.1298 |
| Taxol | MX1 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Taxol | T47DKBLUC | -4.4776 | 0.9657 | -7.7956 | -7.1535 | -7.8857 | 1.9630 | 0.4725 | 0.4725 | 6.3425 |
| Taxol | 600MPE | -4.4776 | 0.8702 | -5.8493 | -4.4776 | -7.3586 | 1.0005 | 0.3500 | 0.6349 | 7.7967 |
| Taxol | HCC2185 | -4.4776 | 0.9451 | -8.0891 | -4.4776 | -8.2188 | 3.3540 | 0.5784 | 0.5784 | 6.7312 |