Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Gefitinib | AU565 | -4.4776 | 0.9681 | -5.6452 | -5.5800 | -5.9334 | 0.9489 | 0.0674 | 0.1471 | 6.9371 |
| Gefitinib | BT-20 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Gefitinib | BT-474 | -4.4776 | 0.8631 | -5.3558 | -5.3557 | -6.1316 | 1.2500 | 0.0000 | 0.0487 | 6.8511 |
| Gefitinib | BT-483 | -4.4776 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 8.6514 |
| Gefitinib | BT-549 | -4.4776 | 0.8774 | -4.7649 | -4.7649 | -4.8099 | 1.0490 | 0.0000 | 0.3521 | 7.9303 |
| Gefitinib | CAMA-1 | -4.4776 | 0.7673 | -4.6501 | -4.4776 | -4.6796 | 3.9950 | 0.3020 | 0.6232 | 8.7188 |
| Gefitinib | HCC1143 | -4.4776 | 0.7888 | -4.8484 | -4.5649 | -5.0588 | 1.0312 | 0.2441 | 0.4962 | 8.4272 |
| Gefitinib | HCC1395 | -4.4776 | 0.8462 | -4.8520 | -4.8394 | -5.1537 | 2.8885 | 0.0433 | 0.2396 | 8.2843 |
| Gefitinib | HCC1419 | -4.4776 | 0.8667 | -4.9419 | -4.9419 | -5.6361 | 1.1230 | 0.0000 | 0.2348 | 7.7876 |
| Gefitinib | HCC1428 | -4.4776 | 0.9555 | -4.8307 | -4.8307 | -4.9709 | 2.5540 | 0.0000 | 0.1114 | 7.6485 |
| Gefitinib | HCC1569 | -4.4776 | 0.9435 | -4.9701 | -4.9701 | -5.2564 | 1.0588 | 0.0000 | 0.2375 | 7.5503 |
| Gefitinib | HCC1806 | -4.4776 | 0.8141 | -5.0403 | -5.0403 | -5.3864 | 0.5684 | 0.0000 | 0.2892 | 7.4082 |
| Gefitinib | HCC1937 | -4.4776 | 0.8494 | -4.7373 | -4.7372 | -5.0343 | 0.8277 | 0.0000 | 0.3792 | 7.8718 |
| Gefitinib | HCC1954 | -4.4776 | 0.7966 | -5.3878 | -5.3876 | -5.6277 | 0.8894 | 0.0000 | 0.1697 | 7.2680 |
| Gefitinib | HCC202 | -4.4776 | 0.8987 | -4.9372 | -4.9372 | -6.0592 | 0.8082 | 0.0000 | 0.2980 | 7.7021 |
| Gefitinib | HCC38 | -4.4776 | 0.7476 | -4.9435 | -4.4776 | -4.9022 | 3.9980 | 0.5579 | 0.5639 | 8.6262 |
| Gefitinib | HCC70 | -4.4776 | 0.8897 | -4.4921 | -4.5561 | -5.0812 | 0.9805 | 0.0000 | 0.5169 | 8.0439 |
| Gefitinib | Hs 578T | -4.4776 | 0.8184 | -4.7687 | -4.7686 | -4.8241 | 2.3305 | 0.0001 | 0.2335 | 8.3697 |
| Gefitinib | MB 157 | -4.4776 | 0.8135 | -4.7573 | -4.7572 | -5.3766 | 1.3280 | 0.0000 | 0.2983 | 7.7218 |
| Gefitinib | MDA-MB-134-VI | -4.4776 | 0.7412 | -4.3340 | -4.4776 | -4.6396 | 2.5020 | 0.0000 | 0.6958 | 8.9418 |
| Gefitinib | MDA-MB-157 | -4.4776 | 0.8676 | -4.7946 | -4.7605 | -4.8727 | 3.0890 | 0.1164 | 0.2283 | 8.1918 |
| Gefitinib | MDA-MB-175-VII | -4.4776 | 0.9467 | -6.0856 | -5.9675 | -6.6138 | 1.1250 | 0.2181 | 0.2273 | 6.4171 |
| Gefitinib | MDA-MB-361 | -4.4776 | 0.9669 | -4.9198 | -4.7648 | -5.1962 | 1.3260 | 0.1255 | 0.3332 | 8.0377 |
| Gefitinib | MDA-MB-436 | -4.4776 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 9.0406 |
| Gefitinib | MDA-MB-453 | -4.4776 | 0.9017 | -5.0927 | -5.0358 | -5.1652 | 3.9970 | 0.1820 | 0.1849 | 8.3260 |