Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| GSK1070916 | HCC1395 | -4.4776 | 0.8934 | -5.5501 | -5.5499 | -6.4736 | 0.6310 | 0.0000 | 0.1761 | 6.6549 |
| GSK1070916 | HCC1419 | -4.4776 | 0.7524 | -5.1307 | -4.4776 | -5.1889 | 3.9980 | 0.6589 | 0.6595 | 8.6094 |
| GSK1070916 | HCC1428 | -4.4776 | 0.9550 | -4.8857 | -4.8856 | -5.6712 | 1.5860 | 0.0000 | 0.1599 | 7.7067 |
| GSK1070916 | HCC1569 | -4.4776 | 0.9060 | -5.6529 | -5.6530 | -6.1004 | 0.5168 | 0.0000 | 0.2019 | 6.5482 |
| GSK1070916 | HCC1806 | -4.4776 | 0.9314 | -5.0186 | -5.0186 | -5.0488 | 2.4110 | 0.0000 | 0.0473 | 7.4139 |
| GSK1070916 | HCC1937 | -4.4776 | 0.8305 | -4.8158 | -4.8552 | -5.7750 | 0.4686 | 0.0000 | 0.3979 | 7.2970 |
| GSK1070916 | HCC1954 | -4.4776 | 0.9120 | -5.3490 | -5.3489 | -5.5470 | 1.2750 | 0.0000 | 0.0774 | 7.4421 |
| GSK1070916 | HCC202 | -4.4776 | 0.8263 | -4.8108 | -4.8108 | -5.8427 | 0.8376 | 0.0000 | 0.3447 | 7.6824 |
| GSK1070916 | HCC38 | -4.4776 | 0.9041 | -5.7636 | -5.7637 | -6.4859 | 0.5460 | 0.0000 | 0.1725 | 6.4217 |
| GSK1070916 | HCC70 | -4.4776 | 0.8789 | -5.6596 | -5.6592 | -6.4477 | 0.4719 | 0.0000 | 0.2000 | 6.6848 |
| GSK1070916 | Hs 578T | -4.4776 | 0.9154 | -5.9386 | -5.9390 | -6.4229 | 0.5351 | 0.0000 | 0.1410 | 6.1417 |
| GSK1070916 | MB 157 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| GSK1070916 | MDA-MB-134-VI | -4.4776 | 0.8155 | -4.5868 | -4.5868 | -5.5744 | 0.5597 | 0.0000 | 0.4864 | 7.9183 |
| GSK1070916 | MDA-MB-157 | -4.4776 | 0.7855 | -5.6706 | -5.6709 | -5.9571 | 0.4644 | 0.0000 | 0.2182 | 6.4360 |
| GSK1070916 | MDA-MB-175-VII | -4.4776 | 0.9124 | -4.8858 | -4.8858 | -5.0396 | 2.8650 | 0.0855 | 0.1022 | 7.8354 |
| GSK1070916 | MDA-MB-361 | -4.4776 | 0.9615 | -5.0034 | -5.0034 | -5.2835 | 2.9475 | 0.0000 | 0.0308 | 7.7162 |
| GSK1070916 | MDA-MB-436 | -4.4776 | 0.7907 | -6.4626 | -5.9265 | -6.7461 | 0.6887 | 0.2865 | 0.3159 | 6.8143 |
| GSK1070916 | MDA-MB-453 | -4.4776 | 0.8573 | -5.1036 | -5.1035 | -5.6475 | 1.3077 | 0.0000 | 0.1426 | 7.3238 |
| GSK1070916 | MDA-MB-468 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| GSK1070916 | T47D | -4.4776 | 0.9317 | -4.7860 | -4.7859 | -5.4249 | 1.3980 | 0.0000 | 0.2704 | 7.9162 |
| GSK1070916 | UACC-812 | -4.4776 | 0.7401 | -5.0020 | -4.4776 | -5.0814 | 3.9990 | 0.6105 | 0.6136 | 9.2304 |
| GSK1070916 | UACC-893 | -4.4776 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 8.7253 |
| GSK1070916 | ZR-75-1 | -4.4776 | 0.8070 | -4.4399 | -4.4776 | -4.9738 | 2.1600 | 0.3143 | 0.6295 | 8.0879 |
| GSK1070916 | 184B5 | -4.4776 | 0.9613 | -5.3762 | -5.3761 | -6.1627 | 0.5692 | 0.0000 | 0.2357 | 7.0319 |
| GSK1070916 | HCC1187 | -4.4776 | 0.9555 | -7.8256 | -7.7783 | -7.9254 | 3.9990 | 0.2321 | 0.2321 | 5.1468 |