Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Doxorubicin | CAMA-1 | -6.2596 | 0.9750 | -6.5136 | -6.5136 | -6.9555 | 1.5700 | 0.0000 | 0.2853 | 8.0312 |
| Doxorubicin | ZR75B | -6.2596 | 0.8591 | -6.8890 | -6.8889 | -7.3287 | 0.3911 | 0.0000 | 0.3620 | 6.9534 |
| Doxorubicin | ZR-75-1 | -6.2596 | 0.9686 | -6.0603 | -6.2596 | -7.1129 | 0.7632 | 0.0000 | 0.5866 | 8.3016 |
| Doxorubicin | UACC-893 | -6.2596 | 0.9220 | -6.7659 | -6.7659 | -7.2336 | 3.0060 | 0.0000 | 0.0296 | 7.4102 |
| Doxorubicin | UACC-812 | -6.2596 | 0.8502 | -6.3713 | -6.3713 | -6.6247 | 1.8830 | 0.0000 | 0.3812 | 8.2791 |
| Doxorubicin | T47D | -6.2596 | 0.8913 | -6.4580 | -6.4460 | -7.2470 | 0.8943 | 0.0146 | 0.3997 | 8.1427 |
| Doxorubicin | MDA-MB-468 | -6.2596 | 0.8596 | -6.9948 | -6.9180 | -7.1414 | 1.9500 | 0.1211 | 0.1824 | 7.4972 |
| Doxorubicin | MDA-MB-453 | -6.2596 | 0.8523 | -6.6610 | -6.6611 | -6.9194 | 2.4350 | 0.0000 | 0.0953 | 7.4383 |
| Doxorubicin | MDA-MB-175-VII | -6.2596 | 0.9332 | -6.6478 | -6.6036 | -6.9876 | 1.9955 | 0.1025 | 0.2936 | 7.9538 |
| Doxorubicin | MDA-MB-157 | -6.2596 | 0.9345 | -6.8059 | -6.8059 | -7.3282 | 1.8710 | 0.0000 | 0.0923 | 7.4851 |
| Doxorubicin | MDA-MB-134-VI | -6.2596 | 0.8403 | -6.2120 | -6.2596 | -6.4295 | 1.8000 | 0.0000 | 0.5502 | 8.3275 |
| Doxorubicin | BT-474 | -6.2596 | 0.9731 | -6.3461 | -6.3460 | -6.5288 | 2.2890 | 0.0003 | 0.3881 | 8.0387 |
| Doxorubicin | HCC1143 | -6.2596 | 0.9684 | -6.7690 | -6.7690 | -6.9395 | 1.4990 | 0.0000 | 0.1470 | 7.5211 |
| Doxorubicin | Hs 578T | -6.2596 | 0.8971 | -6.6679 | -6.6679 | -6.9052 | 0.6556 | 0.0000 | 0.3499 | 7.4580 |