Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Docetaxel | SUM52PE | -5.0000 | 0.9765 | -8.6740 | -8.4669 | -8.7954 | 1.5570 | 0.2588 | 0.2588 | 4.8421 |
| Ixabepilone | Hs 578T | -4.4045 | 0.9537 | -8.6775 | -8.6117 | -8.7153 | 1.3270 | 0.1267 | 0.1267 | 3.5228 |
| Torkinib | MCF 10F | -4.3010 | 0.9683 | -8.7050 | -8.2104 | -8.8465 | 0.5975 | 0.2470 | 0.2488 | 3.9764 |
| Torkinib | UACC-812 | -4.3010 | 0.9736 | -8.7280 | -7.8546 | -10.2600 | 0.3573 | 0.2563 | 0.2753 | 4.2197 |
| Docetaxel | SUM159PT | -5.0000 | 0.9753 | -8.7915 | -8.7477 | -8.8094 | 2.1380 | 0.0956 | 0.0956 | 3.6627 |
| Docetaxel | SUM149PT | -5.0000 | 0.9360 | -8.8090 | -8.6657 | -8.8072 | 2.3100 | 0.2665 | 0.2665 | 4.7876 |
| Torkinib | HCC38 | -4.3010 | 0.9596 | -8.9020 | -8.8385 | -9.6108 | 0.5908 | 0.0409 | 0.0428 | 2.3342 |
| GSK461364 | MDA-MB-157 | -4.4776 | 0.9444 | -9.0436 | -8.9391 | -9.0610 | 2.6360 | 0.2340 | 0.2340 | 3.5893 |
| Ixabepilone | MDA-MB-231 | -4.4045 | 0.9286 | -9.2455 | -9.2112 | -9.2591 | 1.4930 | 0.1324 | 0.1324 | 2.3981 |
| Torkinib | T47DKBLUC | -4.3010 | 0.9063 | -9.3870 | -5.1956 | -9.6065 | 0.4163 | 0.4910 | 0.4949 | 5.3140 |
| Torkinib | T47D | -4.3010 | 0.9460 | -9.4110 | -8.5983 | -9.5701 | 0.4377 | 0.2796 | 0.2838 | 3.7359 |
| Torkinib | HCC70 | -4.3010 | 0.9415 | -9.6690 | -9.5655 | -12.1070 | 0.3058 | 0.0350 | 0.0565 | 2.0727 |
| Torkinib | ZR-75-1 | -4.3010 | 0.9479 | -9.8430 | -8.9499 | -10.7280 | 0.5030 | 0.3223 | 0.3234 | 3.6921 |
| Torkinib | MCF7 | -4.3010 | 0.9482 | -10.1570 | -9.6593 | -10.3750 | 0.4305 | 0.1950 | 0.1974 | 2.6031 |