Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Imatinib | HCC70 | -3.2480 | 0.9722 | -4.5260 | -4.5261 | -4.7307 | 2.4460 | 0.0000 | 0.0007 | 6.5545 |
| Imatinib | Hs 578T | -3.2480 | 0.7789 | -4.2235 | -4.2235 | -4.2478 | 3.9950 | 0.0000 | 0.0001 | 8.6178 |
| Imatinib | MB 157 | -3.2480 | 0.9257 | -4.6250 | -4.6237 | -4.6820 | 3.9870 | 0.0039 | 0.0039 | 6.5279 |
| Imatinib | MDA-MB-134-VI | -3.2480 | 0.9236 | -4.2770 | -4.2771 | -4.5481 | 1.6620 | 0.0000 | 0.0191 | 6.5153 |
| Imatinib | MDA-MB-157 | -3.2480 | 0.9862 | -4.5660 | -4.5652 | -4.7246 | 3.0205 | 0.0033 | 0.0036 | 6.6366 |
| Imatinib | MDA-MB-175-VII | -3.2480 | 0.9700 | -4.8320 | -4.8324 | -5.2006 | 1.4170 | 0.0000 | 0.0057 | 5.9697 |
| Imatinib | MDA-MB-361 | -3.2480 | 0.9895 | -4.4620 | -4.4600 | -4.6177 | 3.8790 | 0.0054 | 0.0054 | 6.8426 |
| Imatinib | MDA-MB-436 | -3.2480 | 0.9531 | -4.5560 | -4.5561 | -4.7613 | 1.5600 | 0.0000 | 0.0090 | 6.5352 |
| Imatinib | MDA-MB-453 | -3.2480 | 0.9413 | -4.7725 | -4.7724 | -5.0029 | 1.5870 | 0.0000 | 0.0046 | 5.9356 |
| Imatinib | MDA-MB-468 | -3.2480 | 0.9814 | -4.8485 | -4.8453 | -4.9340 | 2.4910 | 0.0089 | 0.0091 | 6.0640 |
| Imatinib | T47D | -3.2480 | 0.9692 | -4.6025 | -4.6027 | -4.8049 | 1.7295 | 0.0000 | 0.0054 | 6.3271 |
| Imatinib | UACC-812 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Imatinib | UACC-893 | -3.2480 | 0.9798 | -4.5520 | -4.5520 | -4.7819 | 2.5830 | 0.0000 | 0.0005 | 6.4846 |
| Imatinib | ZR-75-1 | -3.2480 | 0.9815 | -4.4360 | -4.4347 | -4.5865 | 3.2260 | 0.0065 | 0.0066 | 6.9338 |
| Imatinib | 184B5 | -3.2480 | 0.9858 | -4.5110 | -4.5095 | -4.6356 | 2.8725 | 0.0039 | 0.0042 | 6.5564 |
| Imatinib | HCC1187 | -3.2480 | 0.9652 | -4.4730 | -4.4710 | -4.6078 | 3.2240 | 0.0000 | 0.0072 | 6.5760 |
| Imatinib | MCF 10A | -3.2480 | 0.9742 | -4.4440 | -4.4439 | -4.4645 | 3.3880 | 0.0011 | 0.0012 | 6.6451 |
| Imatinib | MCF 10F | -3.2480 | 0.9698 | -4.5325 | -4.5326 | -4.7421 | 2.4455 | 0.0000 | 0.0059 | 6.8208 |
| Imatinib | SUM1315MO2 | -3.2480 | 0.9796 | -4.4840 | -4.4815 | -4.6214 | 3.9990 | 0.0113 | 0.0113 | 7.1171 |
| Imatinib | SUM149PT | -3.2480 | 0.9675 | -4.6360 | -4.6354 | -4.6881 | 3.9880 | 0.0052 | 0.0052 | 6.6917 |
| Imatinib | SUM159PT | -3.2480 | 0.9729 | -4.9070 | -4.9068 | -4.9231 | 3.9930 | 0.0000 | 0.0000 | 6.3954 |
| Imatinib | SUM185PE | -3.2480 | 0.9547 | -4.6860 | -4.6852 | -4.8795 | 2.5860 | 0.0036 | 0.0038 | 6.6258 |
| Imatinib | SUM225CWN | -3.2480 | 0.9795 | -4.6485 | -4.6481 | -4.8764 | 2.4335 | 0.0000 | 0.0006 | 6.5728 |
| Imatinib | SUM229PE | -3.2480 | 0.9703 | -4.8160 | -4.8152 | -5.0068 | 2.6580 | 0.0042 | 0.0066 | 6.0697 |
| Imatinib | SUM52PE | -3.2480 | 0.9540 | -4.3815 | -4.3815 | -4.6729 | 1.3085 | 0.0000 | 0.0348 | 6.8613 |