Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Afatinib | HCC1569 | -4.1759 | 0.9016 | -5.5159 | -5.5154 | NaN | 0.4266 | 0.0000 | 0.2115 | 6.2609 |
| Afatinib | HCC1806 | -4.1759 | 0.9406 | -6.0549 | -6.0553 | -6.3696 | 0.6005 | 0.0000 | 0.0692 | 5.5406 |
| Afatinib | HCC1937 | -4.1759 | 0.8622 | -5.4529 | -5.4531 | -6.0631 | 0.9720 | 0.0000 | 0.0542 | 6.1316 |
| Afatinib | HCC1954 | -4.1759 | 0.9383 | -6.5539 | -6.5441 | -6.9493 | 0.6884 | 0.0078 | 0.0302 | 5.1757 |
| Afatinib | HCC202 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Afatinib | HCC38 | -4.1759 | 0.9583 | -5.6009 | -5.6012 | -5.7817 | 1.3420 | 0.0000 | 0.0121 | 6.1539 |
| Afatinib | HCC70 | -4.1759 | 0.9512 | -5.9179 | -5.9177 | -6.4959 | 0.7242 | 0.0000 | 0.0519 | 5.6958 |
| Afatinib | Hs 578T | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Afatinib | MB 157 | -4.1759 | 0.9103 | -7.8959 | -7.7758 | -8.0522 | 0.7092 | 0.0888 | 0.0909 | 3.8972 |
| Afatinib | MDA-MB-134-VI | -4.1759 | 0.9579 | -5.2049 | -5.2044 | -5.4921 | 1.4820 | 0.0000 | 0.0290 | 6.7286 |
| Afatinib | MDA-MB-157 | -4.1759 | 0.9637 | -5.5169 | -5.5155 | -5.5973 | 4.0000 | 0.0069 | 0.0069 | 6.8951 |
| Afatinib | MDA-MB-175-VII | -4.1759 | 0.8569 | -7.3239 | -7.3144 | -8.2297 | 0.7557 | 0.0082 | 0.0124 | 3.9564 |
| Afatinib | MDA-MB-361 | -4.1759 | 0.9721 | -6.4529 | -6.4528 | -8.2239 | 0.5572 | 0.0000 | 0.0511 | 5.1843 |
| Afatinib | MDA-MB-436 | -4.1759 | 0.9131 | -5.0400 | -5.0401 | -5.3939 | 0.9885 | 0.0000 | 0.1227 | 7.5287 |
| Afatinib | MDA-MB-453 | -4.1759 | 0.9652 | -6.3719 | -6.3716 | -7.0248 | 0.6003 | 0.0000 | 0.0459 | 5.3112 |
| Afatinib | MDA-MB-468 | -4.1759 | 0.9052 | -6.0229 | -6.0233 | -6.3015 | 0.5159 | 0.0000 | 0.1002 | 5.5156 |
| Afatinib | T47D | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Afatinib | UACC-812 | -4.1759 | 0.9313 | -6.8609 | -6.8606 | -8.5554 | 0.4511 | 0.0000 | 0.0579 | 4.5521 |
| Afatinib | UACC-893 | -4.1759 | 0.9419 | -6.5479 | -6.5477 | -8.5022 | 0.4910 | 0.0000 | 0.0641 | 4.8958 |
| Afatinib | ZR-75-1 | -4.1759 | 0.9339 | -5.2789 | -5.2788 | -5.8136 | 1.1760 | 0.0000 | 0.0480 | 6.4619 |
| Afatinib | 184B5 | -4.1759 | 0.9209 | -6.6219 | -6.6223 | -7.1526 | 0.4854 | 0.0000 | 0.0610 | 5.0546 |
| Afatinib | HCC1187 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Afatinib | MCF 10A | -4.1759 | 0.9681 | -7.4799 | -7.4254 | -7.5242 | 1.4410 | 0.0821 | 0.0821 | 4.2860 |
| Afatinib | MCF 10F | -4.1759 | 0.9349 | -6.5439 | -6.5441 | -7.0254 | 0.5651 | 0.0000 | 0.0439 | 5.1668 |
| Afatinib | SUM1315MO2 | -4.1759 | 0.9192 | -5.5239 | -5.5238 | -6.8927 | 0.4672 | 0.0000 | 0.1900 | 6.2413 |