Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Taxol | MCF7 | -4.4776 | 0.9768 | -7.8906 | -7.1065 | -7.8335 | 1.6440 | 0.4743 | 0.4743 | 6.1682 |
| Taxol | SK-BR-3 | -4.4776 | 0.9915 | -7.8636 | -7.8277 | -7.9613 | 3.9990 | 0.1407 | 0.1407 | 4.9198 |
| Taxol | MDA-MB-231 | -4.4776 | 0.9683 | -8.2826 | -8.2094 | -8.3050 | 1.4965 | 0.1313 | 0.1313 | 3.7711 |
| Taxol | AU565 | -4.4776 | 0.9817 | -8.0346 | -8.0127 | -8.1165 | 3.4830 | 0.0920 | 0.0920 | 3.9264 |
| Taxol | BT-20 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Taxol | BT-474 | -4.4776 | 0.9747 | -7.8341 | -7.3713 | -7.9943 | 1.7390 | 0.3738 | 0.3738 | 5.7869 |
| Taxol | BT-483 | -4.4776 | 0.7415 | -5.8896 | -4.4776 | -6.9608 | 0.3466 | 0.5285 | 0.6439 | 7.7105 |
| Taxol | BT-549 | -4.4776 | 0.9814 | -8.1951 | -8.1066 | -8.1839 | 3.1955 | 0.2355 | 0.2355 | 4.5825 |
| Taxol | CAMA-1 | -4.4776 | 0.9765 | -7.9036 | -7.7533 | -7.9616 | 3.9990 | 0.3749 | 0.3749 | 5.6568 |
| Taxol | HCC1143 | -4.4776 | 0.9579 | -7.6816 | -7.4738 | -7.8328 | 1.7125 | 0.2784 | 0.2784 | 5.4383 |
| Taxol | HCC1395 | -4.4776 | 0.8453 | -7.5906 | -7.3406 | -7.7382 | 1.9920 | 0.3410 | 0.3410 | 5.7644 |
| Taxol | HCC1419 | -4.4776 | 0.8868 | -7.8856 | -4.4776 | -7.9362 | 2.2600 | 0.7390 | 0.7390 | 8.0537 |
| Taxol | HCC1428 | -4.4776 | 0.8373 | -7.8311 | -4.4776 | -6.0625 | 1.5830 | 0.7669 | 0.7669 | 8.2442 |
| Taxol | HCC1569 | -4.4776 | 0.9339 | -8.0131 | -4.4776 | -7.9203 | 3.9975 | 0.5523 | 0.5523 | 6.5838 |
| Taxol | HCC1806 | -4.4776 | 0.9897 | -8.0876 | -8.0685 | -8.1579 | 2.7400 | 0.0655 | 0.0655 | 3.6186 |
| Taxol | HCC1937 | -4.4776 | 0.8964 | -7.7206 | -4.4776 | -7.8332 | 1.5660 | 0.5548 | 0.5548 | 6.8888 |
| Taxol | HCC1954 | -4.4776 | 0.9763 | -8.0066 | -7.9811 | -8.1129 | 2.9265 | 0.0778 | 0.0778 | 3.9876 |
| Taxol | HCC202 | -4.4776 | 0.8745 | -7.6526 | -4.4776 | -8.0799 | 0.7451 | 0.5002 | 0.5024 | 6.4149 |
| Taxol | HCC38 | -4.4776 | 0.9849 | -8.0341 | -7.9393 | -8.1832 | 1.9245 | 0.1710 | 0.1710 | 4.3121 |
| Taxol | HCC70 | -4.4776 | 0.9901 | -7.9196 | -7.7982 | -8.1002 | 2.7510 | 0.2306 | 0.2306 | 4.8574 |
| Taxol | Hs 578T | -4.4776 | 0.9832 | -8.2421 | -8.1401 | -8.4267 | 1.4310 | 0.1391 | 0.1391 | 3.9251 |
| Taxol | MB 157 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Taxol | MDA-MB-134-VI | -4.4776 | 0.8627 | -7.9316 | -6.1622 | -8.0456 | 2.4480 | 0.5193 | 0.5193 | 7.5397 |
| Taxol | MDA-MB-157 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Taxol | MDA-MB-175-VII | -4.4776 | 0.8420 | -7.9421 | -4.4776 | -7.7201 | 2.5515 | 0.7305 | 0.7305 | 7.5609 |