Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
---|---|---|---|---|---|---|---|---|---|---|
Baicalein | SK-BR-3 | -3.7773 | 0.8844 | -3.6440 | -3.7773 | -3.9431 | 0.7099 | 0.0000 | 0.5542 | 8.1723 |
Baicalein | MDA-MB-231 | -3.7773 | 0.7666 | -4.6960 | -4.6959 | -4.7338 | 1.0480 | 0.0000 | 0.0983 | 7.7425 |
Baicalein | AU565 | -3.7773 | 0.8913 | -4.2120 | -4.2119 | -4.3325 | 1.5475 | 0.0000 | 0.1877 | 7.7030 |
Baicalein | BT-20 | -3.7773 | 0.7961 | -4.0021 | -3.9589 | -4.2649 | 2.5135 | 0.2047 | 0.4857 | 8.3806 |
Baicalein | BT-474 | -3.7773 | 0.7040 | -4.2351 | -3.7773 | -3.9487 | 4.0000 | 0.7594 | 0.7629 | 9.0503 |
Baicalein | BT-483 | -3.7773 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 8.3948 |
Baicalein | BT-549 | -3.7773 | 0.9586 | -4.6665 | -4.6045 | -4.6742 | 1.8410 | 0.1153 | 0.1353 | 7.3849 |
Baicalein | CAMA-1 | -3.7773 | 0.8522 | -3.9440 | -3.9440 | -4.0538 | 2.0050 | 0.0000 | 0.3165 | 8.0619 |
Baicalein | HCC1143 | -3.7773 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 8.1808 |
Baicalein | HCC1395 | -3.7773 | 0.8655 | -4.7914 | -3.7773 | -4.8004 | 2.7085 | 0.5428 | 0.5533 | 8.1207 |
Baicalein | HCC1419 | -3.7773 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 8.9511 |
Baicalein | HCC1428 | -3.7773 | 0.9101 | -4.1180 | -4.0206 | -4.3724 | 1.7310 | 0.0000 | 0.3754 | 7.8277 |
Baicalein | HCC1569 | -3.7773 | 0.8467 | -3.8842 | -3.8842 | -3.9805 | 1.4770 | 0.0000 | 0.4101 | 7.9050 |
Baicalein | HCC1806 | -3.7773 | 0.7422 | -4.6096 | -4.1230 | -4.4280 | 1.6310 | 0.4196 | 0.4440 | 8.0379 |
Baicalein | HCC1937 | -3.7773 | 0.8195 | -4.4964 | -3.7773 | -4.4328 | 3.9700 | 0.5194 | 0.5201 | 8.6281 |
Baicalein | HCC1954 | -3.7773 | 0.7498 | -4.1183 | -3.7773 | -4.0189 | 4.0000 | 0.4924 | 0.5134 | 8.4142 |
Baicalein | HCC202 | -3.7773 | 0.8892 | -3.8065 | -3.8040 | -4.1598 | 2.4450 | 0.0069 | 0.4628 | 8.4780 |
Baicalein | HCC38 | -3.7773 | 0.9390 | -4.4735 | -4.4400 | -4.5625 | 3.9660 | 0.0911 | 0.0980 | 7.7840 |
Baicalein | HCC70 | -3.7773 | 0.7636 | -3.8761 | -3.7773 | -3.9078 | 3.9995 | 0.2600 | 0.6278 | 8.7109 |
Baicalein | Hs 578T | -3.7773 | 0.9171 | -4.2599 | -4.2499 | -4.2995 | 3.9995 | 0.0427 | 0.0538 | 7.9695 |
Baicalein | MB 157 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
Baicalein | MDA-MB-134-VI | -3.7773 | 0.8520 | -3.7787 | -3.7773 | -4.0364 | 2.9790 | 0.0000 | 0.5592 | 8.3025 |
Baicalein | MDA-MB-157 | -3.7773 | 0.9472 | -4.1167 | -4.1167 | -4.2501 | 2.5480 | 0.0000 | 0.1715 | 7.8950 |
Baicalein | MDA-MB-175-VII | -3.7773 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 8.4733 |
Baicalein | MDA-MB-361 | -3.7773 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 8.9897 |