XMD-12 KiNativ -- single dose experiment - Dataset (ID:20103)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| XMD-12 | HeLa | ABL,ARG | LMTGDTYTAHAGAkFPIK | Activation Loop | 70.4 | 10 | uM |
| XMD-12 | HeLa | ACK | TVSVAVkCLKPDVLSQPEAMDDFIR | Lys1 | 87.9 | 10 | uM |
| XMD-12 | PC-3 | AGK | ATVFLNPAACkGK | ATP | -6.7 | 10 | uM |
| XMD-12 | HeLa | AMPKa1,AMPKa2 | DLkPENVLLDAHMNAK | Lys2 | 88.8 | 10 | uM |
| XMD-12 | PC-3 | AMPKa1,AMPKa2 | DLkPENVLLDAHMNAK | Lys2 | 91.5 | 10 | uM |
| XMD-12 | HeLa | AMPKa1,AMPKa2 | VAVkILNR | Lys1 | 88.7 | 10 | uM |
| XMD-12 | PC-3 | AMPKa1,AMPKa2 | VAVkILNR | Lys1 | 90.3 | 10 | uM |
| XMD-12 | HeLa | ARAF | DLkSNNIFLHEGLTVK | Lys2 | 1.1 | 10 | uM |
| XMD-12 | HeLa | ATR | FYIMMCkPK | ATP | -2.1 | 10 | uM |
| XMD-12 | PC-3 | ATR | FYIMMCkPK | ATP | 16.8 | 10 | uM |
| XMD-12 | HeLa | BRAF | DLkSNNIFLHEDLTVK | Lys2 | -6.9 | 10 | uM |
| XMD-12 | HeLa | CaMK1a | LVAIkCIAK | Lys1 | -16.8 | 10 | uM |
| XMD-12 | HeLa | CaMK2g | TSTQEYAAkIINTK | Lys1 | 19.3 | 10 | uM |
| XMD-12 | PC-3 | CaMK2g | TSTQEYAAkIINTK | Lys1 | 33.0 | 10 | uM |
| XMD-12 | PC-3 | CASK | ETGQQFAVkIVDVAK | Lys1 | 22.4 | 10 | uM |
| XMD-12 | PC-3 | CDK10 | DLkVSNLLMTDK | Lys2 | 81.3 | 10 | uM |
| XMD-12 | PC-3 | CDK11,CDK8 | DLkPANILVMGEGPER | Lys2 | 7.1 | 10 | uM |
| XMD-12 | HeLa | CDK2 | DLkPQNLLINTEGAIK | Lys2 | -11.3 | 10 | uM |
| XMD-12 | PC-3 | CDK2 | DLkPQNLLINTEGAIK | Lys2 | -4.2 | 10 | uM |
| XMD-12 | PC-3 | CDK5 | NRETHEIVALkR | Lys1 | 2.4 | 10 | uM |
| XMD-12 | HeLa | CDK7 | DLkPNNLLLDENGVLK | Lys2 | 62.7 | 10 | uM |
| XMD-12 | PC-3 | CDK9 | DMkAANVLITR | Lys2 | 14.3 | 10 | uM |
| XMD-12 | PC-3 | CHK2 | VAIkIISK | Lys1 | 22.9 | 10 | uM |
| XMD-12 | PC-3 | KC1A | DIkPDNFLMGIGR | Lys2 | 28.1 | 10 | uM |
| XMD-12 | PC-3 | CK1d,CK1e | DVkPDNFLMGLGKK | Lys2 | 11.8 | 10 | uM |