BEZ235 KINOMEscan - Dataset (ID:20096)
Proteins Studied
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LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
---|---|---|---|---|---|---|---|---|---|
200200 | IRAK3 | 200200 | Q9Y616 | Interleukin-1 receptor-associated kinase 3; ASRT5; FLJ13601; IRAK3; IRAKM | KINOMEscan | Wild Type; Partial length | |||
200202 | ITK | 200202 | Q08881 | IL2-inducible T-cell kinase; EMT; ITK; LYK; MGC126257; MGC126258; PSCTK2 | KINOMEscan | Wild Type; Partial length | |||
200203 | JAK1(JH1domain-catalytic) | 200203 | P23458 | Janus kinase 1; JAK1; JAK1A; JAK1B; JAK1-catalytic; JTK3 | KINOMEscan | JH1domain-catalytic | Wild Type; Partial length | ||
200204 | JAK1(JH2domain-pseudokinase) | 200204 | P23458 | Janus kinase 1; JAK1; JAK1~b; JAK1A; JAK1B; JAK1-pseudokinase; JTK3 | KINOMEscan | JH2domain-pseudokinase | Wild Type; Partial length | ||
200207 | JAK2(JH1domain-catalytic) | 200207 | O60674 | Janus kinase 2; JAK2; JAK2-catalytic; JTK10 | KINOMEscan | JH1domain-catalytic | Wild Type; Partial length | ||
200209 | JAK3(JH1domain-catalytic) | 200209 | P52333 | Tyrosine-protein kinase JAK3; Janus kinase 3; JAK-3; L-JAK | KINOMEscan | JH1domain-catalytic | Wild Type; Partial length | ||
200211 | JNK1 | 200211 | P45983 | Mitogen-activated protein kinase 8; JNK; JNK1; JNK1A2; JNK21B1/2; MAPK8; PRKM8; SAPK1 | KINOMEscan | Wild Type; Full length | |||
200212 | MK09 | 200212 | P45984 | Mitogen-activated protein kinase 9; JNK2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; JNK-55; MAPK9; p54a; p54aSAPK; PRKM9; SAPK | KINOMEscan | Wild Type; Full length | |||
200213 | JNK3 | 200213 | P53779 | Mitogen-activated protein kinase 10; FLJ12099; FLJ33785; JNK3; JNK3A; MAPK10; MGC50974; p493F12; p54bSAPK; PRKM10 | KINOMEscan | Wild Type; Partial length | |||
200214 | KIT | 200214 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | Wild Type; Partial length | |||
200217 | KIT(D816V) | 200217 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | D816V | Mutation (D816V); Partial length | ||
200218 | KIT(L576P) | 200218 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | L576P | Mutation (L576P); Partial length | ||
200219 | KIT(V559D) | 200219 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | V559D | Mutation (V559D); Partial length | ||
200220 | KIT(V559D,T670I) | 200220 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | V559D,T670I | Mutation (V559D,T670I); Partial length | ||
200221 | KIT(V559D,V654A) | 200221 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | V559D,V654A | Mutation (V559D,V654A); Partial length | ||
200222 | LATS1 | 200222 | O95835 | LATS, large tumor suppressor, homolog 1 (Drosophila); LATS1; WARTS; wts | KINOMEscan | Wild Type; Partial length | |||
200223 | LATS2 | 200223 | Q9NRM7 | LATS, large tumor suppressor, homolog 2 (Drosophila); FLJ13161; KPM; LATS2 | KINOMEscan | Wild Type; Partial length | |||
200224 | LCK | 200224 | P06239 | Lymphocyte-specific protein tyrosine kinase; LCK; LSK; p56lck; pp58lck; YT16 | KINOMEscan | Wild Type; Partial length | |||
200225 | LIMK1 | 200225 | P53667 | LIM domain kinase 1; LIMK | KINOMEscan | Wild Type; Full length | |||
200226 | LIMK2 | 200226 | P53671 | LIM domain kinase 2; LIMK2 | KINOMEscan | Wild Type; Full length | |||
200227 | LKB1 | 200227 | Q15831 | Serine/threonine kinase 11; LKB1; PJS; STK11 | KINOMEscan | Wild Type; Full length | |||
200228 | LOK | 200228 | O94804 | Serine/threonine-protein kinase 10 | KINOMEscan | Wild Type; Partial length | |||
200231 | LTK | 200231 | P29376 | Leukocyte receptor tyrosine kinase; LTK; TYK1 | KINOMEscan | Wild Type; Partial length | |||
200232 | LYN | 200232 | P07948 | V-yes-1 Yamaguchi sarcoma viral related oncogene homolog; FLJ26625; JTK8; LYN | KINOMEscan | Wild Type; Partial length | |||
200233 | M3K13 | 200233 | O43283 | Mitogen-activated protein kinase kinase kinase 13; LZK; MAP3K13; MEKK13; MGC133196 | KINOMEscan | Wild Type; Full length |