AG1478 KINOMEscan - Dataset (ID:20086)
Proteins Studied
Download: Excel (XLSX), Comma-separated (CSV)
| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 200127 | EGFR(L747-S752del, P753S) | 200127 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L747-S752del, P753S | Mutation (L747-S752del, P753S); Partial length | ||
| 200126 | EGFR(L747-E749del, A750P) | 200126 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L747-E749del, A750P | Mutation (L747-E749del, A750P); Partial length | ||
| 200218 | KIT(L576P) | 200218 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | L576P | Mutation (L576P); Partial length | ||
| 200480 | ALK(L1196M) | 200480 | Q9UM73 | Anaplastic lymphoma receptor tyrosine kinase; ALK; CD246; NBLST3; TFG/ALK | KINOMEscan | L1196M | |||
| 200172 | FLT3(K663Q) | 200172 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | K663Q | Mutation (K663Q); Partial length | ||
| 200171 | FLT3(ITD) | 200171 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | ITD | Mutation (ITD); Partial length | ||
| 200330 | PIK3CA(I800L) | 200330 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | I800L | Mutation (I800L); Partial length | ||
| 200013 | ABL1(H396P)-phosphorylated | 200013 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | H396P | phosphorylated | Mutation (H396P); Partial length | |
| 200012 | ABL1(H396P)-nonphosphorylated | 200012 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | H396P | nonphosphorylated | Mutation (H396P); Partial length | |
| 200329 | PIK3CA(H1047Y) | 200329 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | H1047Y | Mutation (H1047Y); Partial length | ||
| 200328 | PIK3CA(H1047L) | 200328 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | H1047L | Mutation (H1047L); Partial length | ||
| 200125 | EGFR(G719S) | 200125 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | G719S | Mutation (G719S); Partial length | ||
| 200124 | EGFR(G719C) | 200124 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | G719C | Mutation (G719C); Partial length | ||
| 200164 | FGFR3(G697C) | 200164 | P22607 | Fibroblast growth factor receptor 3; ACH; CD333; CEK2; FGFR3; HSFGFR3EX; JTK4 | KINOMEscan | G697C | Mutation (G697C); Partial length | ||
| 200230 | LRRK2(G2019S) | 200230 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2; AURA17; DARDARIN; LRRK2; PARK8; RIPK7; ROCO2 | KINOMEscan | G2019S | Mutation (G2019S); Partial length | ||
| 200010 | ABL1(F317L)-phosphorylated | 200010 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | F317L | phosphorylated | Mutation (F317L); Partial length | |
| 200009 | ABL1(F317L)-nonphosphorylated | 200009 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | F317L | nonphosphorylated | Mutation (F317L); Partial length | |
| 200007 | ABL1(F317I)-phosphorylated | 200007 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | F317I | phosphorylated | Mutation (F317I); Partial length | |
| 200006 | ABL1(F317I)-nonphosphorylated | 200006 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | F317I | nonphosphorylated | Mutation (F317I); Partial length | |
| 200123 | EGFR(E746-A750del) | 200123 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | E746-A750del | Mutation (E746-A750del); Partial length | ||
| 200327 | PIK3CA(E545K) | 200327 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | E545K | Mutation (E545K); Partial length | ||
| 200326 | PIK3CA(E545A) | 200326 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | E545A | Mutation (E545A); Partial length | ||
| 200325 | PIK3CA(E542K) | 200325 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | E542K | Mutation (E542K); Partial length | ||
| 200004 | ABL1(E255K)-phosphorylated | 200004 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | E255K | phosphorylated | Mutation (E255K); Partial length | |
| 200170 | FLT3(D835Y) | 200170 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | D835Y | Mutation (D835Y); Partial length |