XMD8-85 KINOMEscan - Dataset (ID:20076)
Proteins Studied
Download: Excel (XLSX), Comma-separated (CSV)
| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 200131 | EGFR(L861Q) | 200131 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L861Q | Mutation (L861Q); Partial length | ||
| 200331 | PIK3CA(M1043I) | 200331 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | M1043I | Mutation (M1043I); Partial length | ||
| 200260 | MET(M1250T) | 200260 | P08581 | Hepatocyte growth factor receptor; AUTS9; c-Met; HGFR; MET; RCCP2 | KINOMEscan | M1250T | Mutation (M1250T); Partial length | ||
| 200014 | ABL1(M351T) | 200014 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | M351T | |||
| 200371 | RET(M918T) | 200371 | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret; CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; PTC; RET; RET51; RET-ELE1 | KINOMEscan | M918T | Mutation (M918T); Partial length | ||
| 200173 | FLT3(N841I) | 200173 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | N841I | Mutation (N841I); Partial length | ||
| 200016 | ABL1(Q252H) | 200016 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | Q252H | |||
| 200332 | PIK3CA(Q546K) | 200332 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | Q546K | Mutation (Q546K); Partial length | ||
| 200132 | EGFR(S752-I759del) | 200132 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | S752-I759del | Mutation (S752-I759del); Partial length | ||
| 200179 | GCN2(Kin.Dom.2,S808G) | 200179 | Q9P2K8 | Eukaryotic translation initiation factor 2 alpha kinase 4; EIF2AK4; GCN2; KIAA1338 | KINOMEscan | S808G | Kin.Dom.2 | Wild Type; Partial length | |
| 200019 | ABL1(T315I) | 200019 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | T315I | |||
| 200219 | KIT(V559D) | 200219 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | V559D | Mutation (V559D); Partial length | ||
| 200220 | KIT(V559D,T670I) | 200220 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | V559D,T670I | Mutation (V559D,T670I); Partial length | ||
| 200221 | KIT(V559D,V654A) | 200221 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | V559D,V654A | Mutation (V559D,V654A); Partial length | ||
| 200055 | BRAF(V600E) | 200055 | P15056 | V-raf murine sarcoma viral oncogene homolog B1; BRAF; BRAF1; B-RAF1; FLJ95109; MGC126806; MGC138284; RAFB1 | KINOMEscan | V600E | Mutation (V600E); Partial length | ||
| 200372 | RET(V804L) | 200372 | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret; CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; PTC; RET; RET51; RET-ELE1 | KINOMEscan | V804L | Mutation (V804L); Partial length | ||
| 200373 | RET(V804M) | 200373 | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret; CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; PTC; RET; RET51; RET-ELE1 | KINOMEscan | V804M | Mutation (V804M); Partial length | ||
| 200261 | MET(Y1235D) | 200261 | P08581 | Hepatocyte growth factor receptor; AUTS9; c-Met; HGFR; MET; RCCP2 | KINOMEscan | Y1235D | Mutation (Y1235D); Partial length | ||
| 200022 | ABL1(Y253F) | 200022 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | Y253F | |||
| 200046 | AURKC | 200046 | Q9UQB9 | Aurora kinase C; AIE2; AIK3; ARK3; Aur3; AurC; AurC/Aur3; AURKC; aurora-C; STK13 | KINOMEscan | Wild Type; Full length | |||
| 200045 | AURKB | 200045 | Q96GD4 | Aurora kinase B; AIK2; AIM1; AIM-1; ARK2; Aur1; AurB; AurB/Aur1; AURKB; aurkb-sv1; aurkb-sv2; IPL1; STK12; STK5 | KINOMEscan | Wild Type; Partial length | |||
| 200030 | ACVR2B | 200030 | Q13705 | Activin A receptor, type IIB; ActR2B; ACTRIIB; ActR-IIB; ACVR2B; MGC116908 | KINOMEscan | Wild Type; Partial length | |||
| 200044 | AURKA | 200044 | O14965 | Aurora kinase A; AIK; AIRK1; ARK1; Aur2; AURA; AurA/Aur2; AURKA; AURORA2; Aurora-A; Ayk1; BTAK; IAK; IAK1; MGC34538; STK15; STK6; STK7 | KINOMEscan | Wild Type; Partial length | |||
| 200043 | M3K6 | 200043 | O95382 | Mitogen-activated protein kinase kinase kinase 6; ASK2; MAP3K6; MAPKKK6; MEKK6; MEKK6/MAP3K6; MGC125653; MGC20114 | KINOMEscan | Wild Type; Partial length | |||
| 200029 | ACVR2A | 200029 | P27037 | Activin A receptor, type IIA; ActR2; ACTRII; ACVR2; ACVR2A | KINOMEscan | Wild Type; Partial length |