GDC-0941 KINOMEscan - Dataset (ID:20060)

Proteins Studied

LINCS ID Name HMS LINCS ID UniProt ID Alternative Names Provider Mutation Phosphlorylation State Domain Protein Description
200022 ABL1(Y253F) 200022 P00519
C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl
KINOMEscan Y253F
200005 ABL1(F317I) 200005 P00519
C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl
KINOMEscan F317I
200016 ABL1(Q252H) 200016 P00519
C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl
KINOMEscan Q252H
200126 EGFR(L747-E749del, A750P) 200126 P00533
Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61
KINOMEscan L747-E749del, A750P Mutation (L747-E749del, A750P); Partial length
200129 EGFR(L858R) 200129 P00533
Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61
KINOMEscan L858R Mutation (L858R); Partial length
200123 EGFR(E746-A750del) 200123 P00533
Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61
KINOMEscan E746-A750del Mutation (E746-A750del); Partial length
200124 EGFR(G719C) 200124 P00533
Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61
KINOMEscan G719C Mutation (G719C); Partial length
200122 EGFR 200122 P00533
Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61
KINOMEscan Wild Type; Partial length
200130 EGFR(L858R,T790M) 200130 P00533
Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61
KINOMEscan L858R,T790M Mutation (L858R,T790M); Partial length
200128 EGFR(L747-T751del,Sins) 200128 P00533
Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61
KINOMEscan L747-T751del,Sins Mutation (L747-T751del,Sins); Partial length
200127 EGFR(L747-S752del, P753S) 200127 P00533
Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61
KINOMEscan L747-S752del, P753S Mutation (L747-S752del, P753S); Partial length
200132 EGFR(S752-I759del) 200132 P00533
Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61
KINOMEscan S752-I759del Mutation (S752-I759del); Partial length
200131 EGFR(L861Q) 200131 P00533
Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61
KINOMEscan L861Q Mutation (L861Q); Partial length
200125 EGFR(G719S) 200125 P00533
Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61
KINOMEscan G719S Mutation (G719S); Partial length
200369 RAF1 200369 P04049
RAF proto-oncogene serine/threonine-protein kinase; CRAF; c-Raf; NS5; RAF1; Raf-1
KINOMEscan Wild Type; Partial length
200148 ERBB2 200148 P04626
Receptor tyrosine-protein kinase erbB-2; CD340; ERBB2; HER2; HER-2; HER-2/neu; MLN 19; NEU; NGL; TKR1
KINOMEscan Wild Type; Partial length
200443 TRKA 200443 P04629
Neurotrophic tyrosine kinase, receptor, type 1; DKFZp781I14186; MTC; NTRK1; p140-TrkA; TRK; TRK1; TRKA; Trk-A
KINOMEscan Wild Type; Partial length
200197 INSR 200197 P06213
Insulin receptor; CD220; HHF5; INSR; IR
KINOMEscan Wild Type; Partial length
200224 LCK 200224 P06239
Lymphocyte-specific protein tyrosine kinase; LCK; LSK; p56lck; pp58lck; YT16
KINOMEscan Wild Type; Partial length
200177 FYN 200177 P06241
FYN oncogene related to SRC, FGR, YES; FYN; MGC45350; SLK; SYN
KINOMEscan Wild Type; Partial length
200160 FES 200160 P07332
Feline sarcoma oncogene; FES; FPS
KINOMEscan Wild Type; Partial length
200094 CSF1R 200094 P07333
Colony stimulating factor 1 receptor; CD115; C-FMS; CSF1R; CSF-1R; CSF-1-R; CSFR; FIM2; FIM-2; FMS; Fms/CSFR
KINOMEscan Wild Type; Partial length
200465 YES 200465 P07947
Tyrosine-protein kinase Yes; Proto-oncogene tyrosine-protein kinase Yes
KINOMEscan Wild Type; Partial length
200232 LYN 200232 P07948
V-yes-1 Yamaguchi sarcoma viral related oncogene homolog; FLJ26625; JTK8; LYN
KINOMEscan Wild Type; Partial length
200373 RET(V804M) 200373 P07949
Proto-oncogene tyrosine-protein kinase receptor Ret; CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; PTC; RET; RET51; RET-ELE1
KINOMEscan V804M Mutation (V804M); Partial length