GDC-0941 KINOMEscan - Dataset (ID:20060)
Proteins Studied
Download: Excel (XLSX), Comma-separated (CSV)
| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 200031 | ACVRL1 | 200031 | P37023 | Activin A receptor type II-like 1; ACVRL1; ACVRLK1; ALK1; ALK-1; HHT; HHT2; ORW2; SKR3; TSR-I | KINOMEscan | Wild Type; Partial length | |||
| 200433 | TGFBR1 | 200433 | P36897 | Transforming growth factor, beta receptor 1; AAT5; ACVRLK4; ALK5; ALK-5; LDS1A; LDS2A; SKR4; TGFBR1; TGFR-1 | KINOMEscan | Wild Type; Partial length | |||
| 200028 | ACVR1B | 200028 | P36896 | Activin A receptor, type IB; ACTRIB; ACVR1B; ACVRLK4; ALK4; SKR2 | KINOMEscan | Wild Type; Partial length | |||
| 200050 | BMPR1A | 200050 | P36894 | Bone morphogenetic protein receptor, type IA; 10q23del; ACVRLK3; ALK3; BMPR1A; CD292; SKR5 | KINOMEscan | Wild Type; Partial length | |||
| 200168 | FLT3 | 200168 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | Wild Type; Partial length | |||
| 200169 | FLT3(D835H) | 200169 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | D835H | Mutation (D835H); Partial length | ||
| 200170 | FLT3(D835Y) | 200170 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | D835Y | Mutation (D835Y); Partial length | ||
| 200171 | FLT3(ITD) | 200171 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | ITD | Mutation (ITD); Partial length | ||
| 200173 | FLT3(N841I) | 200173 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | N841I | Mutation (N841I); Partial length | ||
| 200172 | FLT3(K663Q) | 200172 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | K663Q | Mutation (K663Q); Partial length | ||
| 200252 | MP2K2 | 200252 | P36507 | Dual specificity mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2; FLJ26075; MAP2K2; MAPKK2; MEK2; MEK2/MAP2K2; MKK2; PRKMK2 | KINOMEscan | Wild Type; Full length | |||
| 200458 | VGFR2 | 200458 | P35968 | Vascular endothelial growth factor receptor 2; kinase insert domain receptor; CD309; FLK1; FLK-1; KDR; KRD-1; Ly73; VEGFR; VEGFR2; VEGFR-2 | KINOMEscan | Wild Type; Partial length | |||
| 200175 | FLT4 | 200175 | P35916 | Fms-related tyrosine kinase 4; FLT4; FLT41; LMPH1A; PCL; VEGFR3 | KINOMEscan | Wild Type; Partial length | |||
| 200435 | TIE1 | 200435 | P35590 | Tyrosine-protein kinase receptor Tie-1; tyrosine kinase with immunoglobulin-like and EGF-like domains 1; JTK14; TIE; TIE1 | KINOMEscan | Wild Type; Partial length | |||
| 200448 | TTK | 200448 | P33981 | TTK protein kinase; CT96; ESK; FLJ38280; MPS1; MPS1L1; PYT; TTK | KINOMEscan | Wild Type; Partial length | |||
| 200181 | GRK4 | 200181 | P32298 | G protein-coupled receptor kinase 4; GPRK2L; GPRK4; GRK4; GRK4a; IT11 | KINOMEscan | Wild Type; Full length | |||
| 200035 | AKT2 | 200035 | P31751 | V-akt murine thymoma viral oncogene homolog 2; AKT2; Akt2/PKBb; PKBb; PKBBETA; PRKBB; RAC-BETA | KINOMEscan | Wild Type; Partial length | |||
| 200034 | AKT1 | 200034 | P31749 | V-akt murine thymoma viral oncogene homolog 1; AKT; AKT1; Akt1/PKBa; MGC99656; PKB; PKBa; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | KINOMEscan | Wild Type; Partial length | |||
| 200154 | ERK4 | 200154 | P31152 | Mitogen-activated protein kinase 4; ERK3; Erk4; MAPK4; p63MAPK; PRKM4 | KINOMEscan | Wild Type; Partial length | |||
| 200047 | AXL | 200047 | P30530 | AXL receptor tyrosine kinase; AXL; JTK11; UFO | KINOMEscan | Wild Type; Partial length | |||
| 200460 | WEE1 | 200460 | P30291 | Wee1-like protein kinase; DKFZp686I18166; FLJ16446; WEE1; WEE1A; WEE1hu | KINOMEscan | Wild Type; Partial length | |||
| 200451 | TYK2(JH2domain-pseudokinase) | 200451 | P29597 | Non-receptor tyrosine-protein kinase TYK2; Tyrosine kinase 2; JTK1; TYK2 | KINOMEscan | JH2domain-pseudokinase | Wild Type; Partial length | ||
| 200450 | TYK2(JH1domain-catalytic) | 200450 | P29597 | Non-receptor tyrosine-protein kinase TYK2; Tyrosine kinase 2; JTK1; TYK2 | KINOMEscan | JH1domain-catalytic | Wild Type; Partial length | ||
| 200231 | LTK | 200231 | P29376 | Leukocyte receptor tyrosine kinase; LTK; TYK1 | KINOMEscan | Wild Type; Partial length | |||
| 200144 | EPHB2 | 200144 | P29323 | Ephrin type-B receptor 2; CAPB; DRT; EK5; EPHB2; EPHT3; ERK; Hek5; MGC87492; PCBC; Tyro5 | KINOMEscan | Wild Type; Partial length |