PLX-4720 KINOMEscan - Dataset (ID:20024)

Proteins Studied

LINCS ID Name HMS LINCS ID UniProt ID Alternative Names Provider Mutation Phosphlorylation State Domain Protein Description
200035 AKT2 200035 P31751
V-akt murine thymoma viral oncogene homolog 2; AKT2; Akt2/PKBb; PKBb; PKBBETA; PRKBB; RAC-BETA
KINOMEscan Wild Type; Partial length
200036 AKT3 200036 Q9Y243
V-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma); AKT3; Akt3/PKBg; DKFZp434N0250; PKBg; PKB-GAMMA; PRKBG; RAC-gamma; RAC-PK-gamma; STK-2
KINOMEscan Wild Type; Partial length
200037 ALK 200037 Q9UM73
Anaplastic lymphoma receptor tyrosine kinase; ALK; CD246; NBLST3; TFG/ALK
KINOMEscan Wild Type; Partial length
200038 AMPK-alpha1 200038 Q13131
Protein kinase, AMP-activated, alpha 2 catalytic subunit; AMPK; AMPKa1; AMPK-alpha1; MGC33776; MGC57364; PRKAA1
KINOMEscan Wild Type; Partial length
200039 AMPK-alpha2 200039 P54646
Protein kinase, AMP-activated, alpha 2 catalytic subunit; AMPK; AMPK2; AMPKa2; AMPK-alpha2; PRKAA; PRKAA2
KINOMEscan Wild Type; Partial length
200040 ANKK1 200040 Q8NFD2
Ankyrin repeat and kinase domain containing 1; ANKK1; PKK2; SgK288
KINOMEscan Wild Type; Partial length
200041 NUAK1 200041 O60285
NUAK family, SNF1-like kinase, 1; ARK5; KIAA0537; NUAK1
KINOMEscan Wild Type; Partial length
200042 M3K5 200042 Q99683
Mitogen-activated protein kinase kinase kinase 5; ASK; ASK/MAP3K5; ASK1; MAP3K5; MAPKKK5; MEKK5
KINOMEscan Wild Type; Partial length
200043 M3K6 200043 O95382
Mitogen-activated protein kinase kinase kinase 6; ASK2; MAP3K6; MAPKKK6; MEKK6; MEKK6/MAP3K6; MGC125653; MGC20114
KINOMEscan Wild Type; Partial length
200044 AURKA 200044 O14965
Aurora kinase A; AIK; AIRK1; ARK1; Aur2; AURA; AurA/Aur2; AURKA; AURORA2; Aurora-A; Ayk1; BTAK; IAK; IAK1; MGC34538; STK15; STK6; STK7
KINOMEscan Wild Type; Partial length
200045 AURKB 200045 Q96GD4
Aurora kinase B; AIK2; AIM1; AIM-1; ARK2; Aur1; AurB; AurB/Aur1; AURKB; aurkb-sv1; aurkb-sv2; IPL1; STK12; STK5
KINOMEscan Wild Type; Partial length
200046 AURKC 200046 Q9UQB9
Aurora kinase C; AIE2; AIK3; ARK3; Aur3; AurC; AurC/Aur3; AURKC; aurora-C; STK13
KINOMEscan Wild Type; Full length
200047 AXL 200047 P30530
AXL receptor tyrosine kinase; AXL; JTK11; UFO
KINOMEscan Wild Type; Partial length
200048 BIKE 200048 Q9NSY1
BMP2 inducible kinase; BIKE; BMP2K; DKFZp434K0614; DKFZp434P0116; HRIHFB2017
KINOMEscan Wild Type; Partial length
200049 BLK 200049 P51451
Tyrosine-protein kinase BLK; B lymphoid tyrosine kinase; BLK; MGC10442
KINOMEscan Wild Type; Partial length
200050 BMPR1A 200050 P36894
Bone morphogenetic protein receptor, type IA; 10q23del; ACVRLK3; ALK3; BMPR1A; CD292; SKR5
KINOMEscan Wild Type; Partial length
200051 BMPR1B 200051 O00238
Bone morphogenetic protein receptor, type IB; ALK6; ALK-6; BMPR1B; CDw293
KINOMEscan Wild Type; Partial length
200052 BMPR2 200052 Q13873
Bone morphogenetic protein receptor, type II (serine/threonine kinase); BMPR2; BMPR3; BMPR-II; BMR2; BRK-3; FLJ41585; FLJ76945; PPH1; T-ALK
KINOMEscan Wild Type; Partial length
200053 BMX 200053 P51813
BMX non-receptor tyrosine kinase; BMX; ETK; Etk/BMX; PSCTK2; PSCTK3
KINOMEscan Wild Type; Full length
200054 BRAF 200054 P15056
Serine/threonine-protein kinase B-raf; v-raf murine sarcoma viral oncogene homolog B1; BRAF1; RAFB1
KINOMEscan Wild Type; Partial length
200055 BRAF(V600E) 200055 P15056
V-raf murine sarcoma viral oncogene homolog B1; BRAF; BRAF1; B-RAF1; FLJ95109; MGC126806; MGC138284; RAFB1
KINOMEscan V600E Mutation (V600E); Partial length
200056 PTK6 200056 Q13882
Protein tyrosine kinase 6; BRK; FLJ42088; PTK6
KINOMEscan Wild Type; Partial length
200057 BRSK1 200057 Q8TDC3
BR serine/threonine kinase 1; BRSK1; FLJ43009; KIAA1811
KINOMEscan Wild Type; Partial length
200058 BRSK2 200058 Q8IWQ3
BR serine/threonine kinase 2; BRSK2; C11orf7; FLJ41362; PEN11B; SAD1; STK29
KINOMEscan Wild Type; Full length
200059 BTK 200059 Q06187
Tyrosine-protein kinase BTK; agammaglobulinemia tyrosine kinase; AGMX1; ATK; BPK
KINOMEscan Wild Type; Full length