JIMT-1 - Cell Line (ID:51118)

HMS LINCS ID: 51118
Name: JIMT-1
Alternative Names:
LINCS ID:
Alternative ID:
Parent Cell Line:
Reference Source: Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures ACC 589
Organism: Homo sapiens
Organ: breast
Tissue:
Cell Type: epithelial
Details of Cell Type:
Donor Sex: female
Donor Age: 62
Donor Ethnicity:
Donor Health Status:
Disease: DOID:3005, invasive ductal carcinoma
Details of Disease: breast ductal adenocarcinoma
Production Details: From DSMZ: established from the pleural effusion of a 62-year-old woman with ductal breast cancer (grade 3 invasive, T2N1M0) after postoperative radiation in 2003; cell line was described to be insensitive to HER-2-inhibiting drugs, e.g. trastuzumab (Herceptin)
Genetic Modification(s): none
Known Mutations: HER-2 amplification
Citation Information for Mutations: Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures ACC 589
Verification Reference Profile:
Growth Properties: adherent; From DSMZ: epithelial-like cells growing in monolayers
Recommended Culture Conditions: From DSMZ: Medium: 90% Dulbecco's MEM + 10% h.i. FBS. Subculture: Split confluent culture 1:2 to 1:8 every 2-4 days using trypsin/EDTA. Seed out at ca. 1 x 106 cells/80 cm2. Incubation: at 37°C with 5% CO2. Doubling time: ca. 30-40 hours.
Relevant Citations: PMID 15634652
Usage Note:
Comments:
Date Publicly Available: 2016-08-24
Most Recent Update: 2016-08-24

Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20268
Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates.
Analysis
20269
Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics.
Analysis

Batch Information:

HMS LINCS Batch ID Provider Provider Catalog ID Provider Batch ID
51118-1 Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures ACC 589