JIMT-1 - Cell Line (ID:51118)

HMS LINCS ID: 51118
Name: JIMT-1
Alternative Names:
LINCS ID:
Alternative ID:
Parent Cell Line:
Reference Source: Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures ACC 589
Organism: Homo sapiens
Organ: breast
Tissue:
Cell Type: epithelial
Details of Cell Type:
Donor Sex: female
Donor Age: 62
Donor Ethnicity:
Donor Health Status:
Disease: DOID:3005, invasive ductal carcinoma
Details of Disease: breast ductal adenocarcinoma
Production Details: From DSMZ: established from the pleural effusion of a 62-year-old woman with ductal breast cancer (grade 3 invasive, T2N1M0) after postoperative radiation in 2003; cell line was described to be insensitive to HER-2-inhibiting drugs, e.g. trastuzumab (Herceptin)
Genetic Modification(s): none
Known Mutations: HER-2 amplification
Citation Information for Mutations: Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures ACC 589
Verification Reference Profile:
Growth Properties: adherent; From DSMZ: epithelial-like cells growing in monolayers
Recommended Culture Conditions: From DSMZ: Medium: 90% Dulbecco's MEM + 10% h.i. FBS. Subculture: Split confluent culture 1:2 to 1:8 every 2-4 days using trypsin/EDTA. Seed out at ca. 1 x 106 cells/80 cm2. Incubation: at 37°C with 5% CO2. Doubling time: ca. 30-40 hours.
Relevant Citations: PMID 15634652
Usage Note:
Comments:
Date Publicly Available: 2016-08-24
Most Recent Update: 2016-08-24

Batch Information for HMSL51118-1:

HMS LINCS Batch ID: 51118-1
Provider: Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures
Provider Catalog ID: ACC 589
Provider Batch ID:
Source Information: Obtained by Joe Gray's group (Oregon Health & Science University) from DSMZ
Date Received:
HMS QC Outcome:
Transient Modification(s):
Comments:
Date Publicly Available: 2016-08-24
Most Recent Update: 2016-08-24