| HMS LINCS ID:
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51118
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| Name:
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JIMT-1
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| Alternative Names:
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| LINCS ID:
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| Alternative ID:
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| Parent Cell Line:
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| Reference Source:
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Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures ACC 589
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| Organism:
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Homo sapiens
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| Organ:
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breast
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| Tissue:
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| Cell Type:
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epithelial
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| Details of Cell Type:
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| Donor Sex:
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female
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| Donor Age:
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62
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| Donor Ethnicity:
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| Donor Health Status:
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| Disease:
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DOID:3005, invasive ductal carcinoma
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| Details of Disease:
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breast ductal adenocarcinoma
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| Production Details:
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From DSMZ: established from the pleural effusion of a 62-year-old woman with ductal breast cancer (grade 3 invasive, T2N1M0) after postoperative radiation in 2003; cell line was described to be insensitive to HER-2-inhibiting drugs, e.g. trastuzumab (Herceptin)
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| Genetic Modification(s):
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none
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| Known Mutations:
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HER-2 amplification
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| Citation Information for Mutations:
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Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures ACC 589
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| Verification Reference Profile:
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| Growth Properties:
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adherent; From DSMZ: epithelial-like cells growing in monolayers
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| Recommended Culture Conditions:
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From DSMZ: Medium: 90% Dulbecco's MEM + 10% h.i. FBS. Subculture: Split confluent culture 1:2 to 1:8 every 2-4 days using trypsin/EDTA. Seed out at ca. 1 x 106 cells/80 cm2. Incubation: at 37°C with 5% CO2. Doubling time: ca. 30-40 hours.
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| Relevant Citations:
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PMID 15634652
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| Usage Note:
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| Comments:
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| Date Publicly Available:
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2016-08-24
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| Most Recent Update:
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2016-08-24
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