CAL-120 - Cell Line (ID:51110)
| HMS LINCS ID: | 51110 |
| Name: | CAL-120 |
| Alternative Names: | |
| LINCS ID: | |
| Alternative ID: | CLO_0002179 |
| Parent Cell Line: | |
| Reference Source: | Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures ACC 459 |
| Organism: | Homo sapiens |
| Organ: | breast |
| Tissue: | |
| Cell Type: | |
| Details of Cell Type: | |
| Donor Sex: | female |
| Donor Age: | 43 |
| Donor Ethnicity: | |
| Donor Health Status: | |
| Disease: | DOID:3458, breast adenocarcinoma |
| Details of Disease: | breast adenocarcinoma |
| Production Details: | From DSMZ: established from the pleural effusion of a metastatic breast adenocarcinoma in 1991 |
| Genetic Modification(s): | none |
| Known Mutations: | |
| Citation Information for Mutations: | |
| Verification Reference Profile: | |
| Growth Properties: | adherent; From DSMZ: heterogenous population with epithelial-like and fibroblast-like adherent cells growing in monolayers |
| Recommended Culture Conditions: | From DSMZ: Medium: 90% Dulbecco's MEM + 10% h.i. FBS. Subculture: split confluent culture 1:2 every 2-3 days using trypsin/EDTA; seed out at ca. 1 x 106 cells/175 cm2. Incubation: at 37°C with 10% CO2. Doubling time: ca. 50-60 hours. |
| Relevant Citations: | |
| Usage Note: | |
| Comments: | |
| Date Publicly Available: | 2016-08-24 |
| Most Recent Update: | 2016-08-24 |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20268 | Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. | Analysis |
| 20269 | Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics. | Analysis |
| 20343 | Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values | Microscopy/Imaging |
| 20344 | Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 2 of 2: Calculated dose response metrics | Analysis |
| 20348 | Breast Cancer Profiling Project, Gene Expression 1: Baseline mRNA sequencing on 35 breast cell lines | RNA-Seq |
| 20352 | Breast Cancer Profiling Project – Proteomics 1: 1 total proteome dataset for a 35-cell line breast cancer panel under basal conditions | Proteomics |
| 20353 | Breast Cancer Profiling Project – Proteomics 2: 1 phosphoproteome dataset (including phosphotyrosine enrichment) for a 35-cell line breast cancer panel under basal conditions | Proteomics |
| 20354 | Breast Cancer Profiling Project, Drug Sensitivity phase II: Fixed-cell GR measures of 33 breast cell lines and PDX lines to 16 small molecule perturbagens from library plate II. Dataset 1 of 2: Normalized growth rate inhibition values | Microscopy/Imaging |
| 20355 | Breast Cancer Profiling Project, Drug Sensitivity phase II: Fixed-cell GR measures of 33 breast cell lines and PDX lines to 16 small molecule perturbagens from library plate II. Dataset 2 of 2: Calculated dose response metrics | Analysis |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Catalog ID | Provider Batch ID |
|---|---|---|---|
| 51110-1 | Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures | ACC 459 | |
| 51110-2 | Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures | ACC-459 |