| HMS LINCS ID:
|
80078
|
| Name:
|
Cetuximab
|
| Alternative Names:
|
Erbitux
|
| Clone Name:
|
|
| Resource Identification Initiative ID:
|
|
| LINCS ID:
|
|
| Type:
|
engineered
|
| Nominal Protein Target(s):
|
EGFR
|
| Nominal Protein Target HMS LINCS ID(s):
|
200507
|
| Nominal Non-protein Target:
|
|
| Organism of Nominal Target:
|
Homo sapiens
|
| Other Target Information:
|
binds specifically to the extracellular domain of human EGFR (source: Bristol-Myers Squibb)
|
| Other Human Protein Target HMS LINCS ID(s):
|
|
| Immunogen:
|
|
| Immunogen Sequence:
|
|
| Fc Domain Source Species:
|
human
|
| Clonality:
|
monoclonal
|
| Fc Domain Isotype:
|
IgG1
|
| Source Organism for Production:
|
murine myeloma cells
|
| Production Details:
|
recombinant, human/mouse chimeric monoclonal antibody (chimerized from mouse monoloclonal antibody 225); composed of the Fv regions of the murine anti-EGFR antibody with human IgG1 heavy and kappa light chain constant regions; produced in mammalian (murine myeloma) cell culture (source: Bristol-Myers Squibb)
|
| Conjugate or Label:
|
|
| Labeling Details:
|
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| Relevant Citations:
|
|
| Comments:
|
|
| Date Publicly Available:
|
2016-09-16
|
| Most Recent Update:
|
2016-09-16
|