Pertuzumab - Antibody (ID:80077)

HMS LINCS ID: 80077
Name: Pertuzumab
Alternative Names: Omnitag; Perjeta
Clone Name: rhuMAb2C4
Resource Identification Initiative ID:
LINCS ID:
Type: engineered
Nominal Protein Target(s): erbB-2
Nominal Protein Target HMS LINCS ID(s): 200509
Nominal Non-protein Target:
Organism of Nominal Target: Homo sapiens
Other Target Information: targets the extracellular dimerization domain (Subdomain II) of human HER2 (source: Genentech)
Other Human Protein Target HMS LINCS ID(s):
Immunogen:
Immunogen Sequence:
Fc Domain Source Species: human
Clonality: monoclonal
Fc Domain Isotype:
Source Organism for Production: Chinese Hamster Ovary cells
Production Details: humanized monoclonal antibody derived from mouse monoclonal antibody 2C4; produced by recombinant DNA technology in a mammalian cell (Chinese Hamster Ovary) culture containing the antibiotic gentamicin (source: Genentech)
Conjugate or Label:
Labeling Details:
Relevant Citations:
Comments:
Date Publicly Available: 2016-09-16
Most Recent Update: 2016-09-16

Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20268
Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates.
Analysis
20269
Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics.
Analysis

Batch Information:

HMS LINCS Batch ID Provider Provider Catalog ID Provider Batch ID
80077-1 Genentech rhuMAb 2C4 (G186CP R9805A)