SB202190 - Small Molecule (ID:10441-101)
| HMS LINCS ID: |
10441-101
|
| Name: | SB202190 |
| Alternative Names: | |
| LINCS ID: | |
| PubChem CID: | 5353940 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 331.11 |
| InChi: | InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24) |
| InChi Key: | QHKYPYXTTXKZST-UHFFFAOYSA-N |
| SMILES: | OC1=CC=C(C2=NC(C3=CC=C(F)C=C3)=C(C4=CC=NC=C4)N2)C=C1 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
GCGR, MAPK10, MAPK13, MAPK14, NLK | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | ACVR1B, CDC42BPG, CIT, CSNK1D, CSNK1E, GAK, MAPK11, MAPK9, PRKACB, RIPK2 |
3 (equivalent to 1µM ≤ Kd < 10 µM) | ACVR1, ACVR2B, AIM1, ALK, AURKA, AURKB, BRAF, BTK, CAMK1D, CAMK2A, CAMKK2, CDC42BPB, CDK5, CDK7, CDK8, CDK9, CHEK1, CLK2, CLK4, CSF1R, CSNK1A1, CSNK1A1L, DDR1, DDR2, DYRK1A, DYRK1B, EGFR, EPHA6, FGFR1, FLG, FLT1, FRK, FYN, GRK5, GSK3A, GSK3B, HCK, IGF1R, IKBKE, KDR, LATS2, LCK, LIMK1, LRRK2, LTK, MAP2K1, MAP2K2, MAP3K10, MAP4K2, MAP4K4, MAPK12, MAPK8, MARK3, MARK4, MELK, MET, MST1R, NEK2, NTRK1, NTRK2, NTRK3, PAK4, PDGFRA, PDGFRB, PIM1, PRKAA1, PRKACA, PRKCQ, PRKD3, PRKX, PTK2, PTK6, RAF1, ROCK1, ROCK2, ROS1, RPS6KA1, RPS6KA3, RPS6KA6, SGK2, SIK2, SLK, STK32B, STK36, TAOK1, TBK1, TKT, TNIK, TNK2, TTK, Tuba1a, TYRO3 |
10 (confirmed non-binding) |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10441-101-1 | MedChem Express | 14381 |
(Kd <100 nM)