Baricitinib - Small Molecule (ID:10354-101)

HMS LINCS ID: 10354-101
Name: Baricitinib
Alternative Names: INCB028050; LY3009104
LINCS ID: LSM-6709
PubChem CID: 44205240
ChEBI ID:
ChEMBL ID:
Molecular Mass: 371.12
InChi: InChI=1S/C16H17N7O2S/c1-2-26(24,25)22-9-16(10-22,4-5-17)23-8-12(7-21-23)14-13-3-6-18-15(13)20-11-19-14/h3,6-8,11H,2,4,9-10H2,1H3,(H,18,19,20)
InChi Key: XUZMWHLSFXCVMG-UHFFFAOYSA-N
SMILES: CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
JAK1, JAK2, TYK2
2
(equivalent to 100 nM ≤ Kd < 1µM)
BMP2K, CAMK2A, JAK3, MAP3K2, PRPF4B, ROCK1, ROCK2
10
(confirmed non-binding)
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Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20000
Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library.
Analysis
20227
Baricitinib KINOMEscan
KINOMEscan

Batch Information:

HMS LINCS Batch ID Provider Provider Batch ID
10354-101-1 Selleck Chemicals S285101