ALW-II-38-3 - Small Molecule (ID:10002-101)

HMS LINCS ID: 10002-101
Name: ALW-II-38-3
Alternative Names:
LINCS ID: LSM-1002
PubChem CID: 24880028
ChEBI ID:
ChEMBL ID:
Molecular Mass: 469.14
InChi: InChI=1S/C23H18F3N5O3/c1-13-3-4-17(10-19(13)30-22(33)20-5-6-28-34-20)29-21(32)15-7-16(23(24,25)26)9-18(8-15)31-11-14(2)27-12-31/h3-12H,1-2H3,(H,29,32)(H,30,33)
InChi Key: IYUFHBXMTTXZBE-UHFFFAOYSA-N
SMILES: CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC(=O)C4=CC=NO4
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
2
(equivalent to 100 nM ≤ Kd < 1µM)
ABL2, BRAF, CSF1R, DDR1, DDR2, EPHA2, EPHA3, EPHA4, EPHA5, EPHA8, EPHB2, EPHB3, EPHB4, FRK, KIT, MAPK11, MAPK14, PDGFRA, PDGFRB, SRC
10
(confirmed non-binding)
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Batch Information for HMSL10002-101-1:

HMS LINCS Batch ID: 10002-101-1
Provider: Nathanael Gray (DFCI)
Provider Batch ID: ALW-II-38-3-1
Salt: 101
Molecular Formula: C23H18F3N5O3
Molecular Weight: 469.42
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2011-07-15
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10002-101-1:

Date HMS QC Outcome Comment Files
03/13/2015 PASS HMSL10002-101-1_LCMS.pdf