Proteins
Download: Excel (XLSX), Comma-separated (CSV)
| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 200172 | FLT3(K663Q) | 200172 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | K663Q | Mutation (K663Q); Partial length | ||
| 200218 | KIT(L576P) | 200218 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | L576P | Mutation (L576P); Partial length | ||
| 200126 | EGFR(L747-E749del, A750P) | 200126 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L747-E749del, A750P | Mutation (L747-E749del, A750P); Partial length | ||
| 200127 | EGFR(L747-S752del, P753S) | 200127 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L747-S752del, P753S | Mutation (L747-S752del, P753S); Partial length | ||
| 200128 | EGFR(L747-T751del,Sins) | 200128 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L747-T751del,Sins | Mutation (L747-T751del,Sins); Partial length | ||
| 200129 | EGFR(L858R) | 200129 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L858R | Mutation (L858R); Partial length | ||
| 200130 | EGFR(L858R,T790M) | 200130 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L858R,T790M | Mutation (L858R,T790M); Partial length | ||
| 200131 | EGFR(L861Q) | 200131 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L861Q | Mutation (L861Q); Partial length | ||
| 200331 | PIK3CA(M1043I) | 200331 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | M1043I | Mutation (M1043I); Partial length | ||
| 200260 | MET(M1250T) | 200260 | P08581 | Hepatocyte growth factor receptor; AUTS9; c-Met; HGFR; MET; RCCP2 | KINOMEscan | M1250T | Mutation (M1250T); Partial length | ||
| 200015 | ABL1(M351T)-phosphorylated | 200015 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | M351T | phosphorylated | Mutation (M351T); Partial length | |
| 200371 | RET(M918T) | 200371 | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret; CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; PTC; RET; RET51; RET-ELE1 | KINOMEscan | M918T | Mutation (M918T); Partial length | ||
| 200173 | FLT3(N841I) | 200173 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | N841I | Mutation (N841I); Partial length | ||
| 200018 | ABL1(Q252H)-phosphorylated | 200018 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | Q252H | phosphorylated | Mutation (Q252H); Partial length | |
| 200017 | ABL1(Q252H)-nonphosphorylated | 200017 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | Q252H | nonphosphorylated | Mutation (Q252H); Partial length | |
| 200332 | PIK3CA(Q546K) | 200332 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | Q546K | Mutation (Q546K); Partial length | ||
| 200174 | FLT3(R834Q) | 200174 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | R834Q | Mutation (R834Q); Partial length | ||
| 200132 | EGFR(S752-I759del) | 200132 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | S752-I759del | Mutation (S752-I759del); Partial length | ||
| 200020 | ABL1(T315I)-nonphosphorylated | 200020 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | T315I | nonphosphorylated | Mutation (T315I); Partial length | |
| 200021 | ABL1(T315I)-phosphorylated | 200021 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | T315I | phosphorylated | Mutation (T315I); Partial length | |
| 200133 | EGFR(T790M) | 200133 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | T790M | Mutation (T790M); Partial length | ||
| 200219 | KIT(V559D) | 200219 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | V559D | Mutation (V559D); Partial length | ||
| 200220 | KIT(V559D,T670I) | 200220 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | V559D,T670I | Mutation (V559D,T670I); Partial length | ||
| 200221 | KIT(V559D,V654A) | 200221 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | V559D,V654A | Mutation (V559D,V654A); Partial length | ||
| 200055 | BRAF(V600E) | 200055 | P15056 | V-raf murine sarcoma viral oncogene homolog B1; BRAF; BRAF1; B-RAF1; FLJ95109; MGC126806; MGC138284; RAFB1 | KINOMEscan | V600E | Mutation (V600E); Partial length |