Proteins

LINCS ID Name HMS LINCS ID UniProt ID Alternative Names Provider Mutation Phosphlorylation State Domain Protein Description
200172 FLT3(K663Q) 200172 P36888
Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1
KINOMEscan K663Q Mutation (K663Q); Partial length
200218 KIT(L576P) 200218 P10721
V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR
KINOMEscan L576P Mutation (L576P); Partial length
200126 EGFR(L747-E749del, A750P) 200126 P00533
Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61
KINOMEscan L747-E749del, A750P Mutation (L747-E749del, A750P); Partial length
200127 EGFR(L747-S752del, P753S) 200127 P00533
Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61
KINOMEscan L747-S752del, P753S Mutation (L747-S752del, P753S); Partial length
200128 EGFR(L747-T751del,Sins) 200128 P00533
Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61
KINOMEscan L747-T751del,Sins Mutation (L747-T751del,Sins); Partial length
200129 EGFR(L858R) 200129 P00533
Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61
KINOMEscan L858R Mutation (L858R); Partial length
200130 EGFR(L858R,T790M) 200130 P00533
Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61
KINOMEscan L858R,T790M Mutation (L858R,T790M); Partial length
200131 EGFR(L861Q) 200131 P00533
Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61
KINOMEscan L861Q Mutation (L861Q); Partial length
200331 PIK3CA(M1043I) 200331 P42336
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha
KINOMEscan M1043I Mutation (M1043I); Partial length
200260 MET(M1250T) 200260 P08581
Hepatocyte growth factor receptor; AUTS9; c-Met; HGFR; MET; RCCP2
KINOMEscan M1250T Mutation (M1250T); Partial length
200015 ABL1(M351T)-phosphorylated 200015 P00519
C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl
KINOMEscan M351T phosphorylated Mutation (M351T); Partial length
200371 RET(M918T) 200371 P07949
Proto-oncogene tyrosine-protein kinase receptor Ret; CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; PTC; RET; RET51; RET-ELE1
KINOMEscan M918T Mutation (M918T); Partial length
200173 FLT3(N841I) 200173 P36888
Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1
KINOMEscan N841I Mutation (N841I); Partial length
200018 ABL1(Q252H)-phosphorylated 200018 P00519
C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl
KINOMEscan Q252H phosphorylated Mutation (Q252H); Partial length
200017 ABL1(Q252H)-nonphosphorylated 200017 P00519
C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl
KINOMEscan Q252H nonphosphorylated Mutation (Q252H); Partial length
200332 PIK3CA(Q546K) 200332 P42336
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha
KINOMEscan Q546K Mutation (Q546K); Partial length
200174 FLT3(R834Q) 200174 P36888
Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1
KINOMEscan R834Q Mutation (R834Q); Partial length
200132 EGFR(S752-I759del) 200132 P00533
Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61
KINOMEscan S752-I759del Mutation (S752-I759del); Partial length
200021 ABL1(T315I)-phosphorylated 200021 P00519
C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl
KINOMEscan T315I phosphorylated Mutation (T315I); Partial length
200020 ABL1(T315I)-nonphosphorylated 200020 P00519
C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl
KINOMEscan T315I nonphosphorylated Mutation (T315I); Partial length
200133 EGFR(T790M) 200133 P00533
Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61
KINOMEscan T790M Mutation (T790M); Partial length
200219 KIT(V559D) 200219 P10721
V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR
KINOMEscan V559D Mutation (V559D); Partial length
200220 KIT(V559D,T670I) 200220 P10721
V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR
KINOMEscan V559D,T670I Mutation (V559D,T670I); Partial length
200221 KIT(V559D,V654A) 200221 P10721
V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR
KINOMEscan V559D,V654A Mutation (V559D,V654A); Partial length
200055 BRAF(V600E) 200055 P15056
V-raf murine sarcoma viral oncogene homolog B1; BRAF; BRAF1; B-RAF1; FLJ95109; MGC126806; MGC138284; RAFB1
KINOMEscan V600E Mutation (V600E); Partial length