LINCS MCF 10A Common Project: Highly-multiplexed imaging by Cyclic Immunofluorescence (CycIF) of protein levels and protein phosphorylation states in the MCF 10A breast cell line treated with 8 small molecule perturbagens. Dataset 4 of 6: Nuclear fluorescent intensity measurements at 48 hr. - Dataset (ID:20306)

Small Molecules Studied

  • 8 Small Molecules
HMS LINCS ID Name Alternative Names LINCS ID Structure Image PubChem CID
10018-5 Neratinib
HKI-272
LSM-42778 53398697
10020-5 Dasatinib
BMS-354825; Sprycel
LSM-1020 3062316
10071-2 Palbociclib
PD0332991
LSM-1071 5330286
10102-7 Taxol
Paclitaxel
LSM-1102 441276
10142-4 Trametinib
GSK-1120212; GSK1120212; GSK1120212B; JTP-74057
LSM-1143 11707110
10233-4 Alpelisib
BYL719
LSM-4256 56649450
10250-3 Etoposide LSM-6348 36462
10282-4 Vorinostat
suberoylanilide hydroxamic acid (SAHA); Zolinza
LSM-3828 5311
  • 8 Small Molecules