Highly-multiplexed imaging by Cyclic Immunofluorescence (CycIF) of protein levels and protein phosphorylation states in the MCF 10A breast cell line treated with EGF or four kinase inhibitors - Dataset (ID:20267)
- Detail
- Small Molecules Studied
- Cell Lines Studied
- Proteins Studied
- Antibodies Studied
- Other Reagents Studied
- Results
Proteins Studied
Download: Excel (XLSX), Comma-separated (CSV)
| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 201308 | K6B | 201308 | P04259 | Keratin, type II cytoskeletal 6B; Cytokeratin-6B; CK-6B; Keratin-6B; Type-II keratin Kb10 | |||||
| 201309 | K6C | 201309 | P48668 | Keratin, type II cytoskeletal 6C; Cytokeratin-6C; CK-6C; Cytokeratin-6E; CK-6E; Keratin K6h; Keratin-6C; Type-II keratin Kb12 | |||||
| 201310 | K8 | 201310 | P05787 | Keratin, type II cytoskeletal 8; Cytokeratin-8; CK-8; Type-II keratin Kb8 | |||||
| 201296 | KI-67 | 201296 | P46013 | Antigen KI-67 | |||||
| 200537 | mTOR | 200537 | P42345 | Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; Mechanistic target of rapamycin; Rapamycin and FKBP12 target 1; Rapamycin target protein 1 | |||||
| 201349 | NF-kB p65 | 201349 | Q04206 | Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 | |||||
| 201295 | p21 | 201295 | P38936 | Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6 | |||||
| 201344 | p27Kip1 | 201344 | P46527 | Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27 | |||||
| 200543 | p53 | 200543 | P04637 | Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53 | |||||
| 201343 | PARP-1 (D214-cleaved) | 201343 | P09874 | D214-cleaved | |||||
| 201302 | PCNA | 201302 | P12004 | Proliferating cell nuclear antigen; Cyclin | |||||
| 201335 | Rb (pS807) | 201335 | P06400 | pS807 | |||||
| 201297 | Rb (pS807; pS811) | 201297 | P06400 | pS807; pS811 | |||||
| 201336 | Rb (pS811) | 201336 | P06400 | pS811 | |||||
| 201342 | S6 | 201342 | P62753 | 40S ribosomal protein S6, Phosphoprotein NP33 | |||||
| 201298 | S6 (pS235; pS236) | 201298 | P62753 | pS235; pS236 | |||||
| 201299 | S6 (pS240; pS244) | 201299 | P62753 | pS240; pS244 | |||||
| 200598 | VEGFR-2 | 200598 | P35968 | Vascular endothelial growth factor receptor 2; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; KDR; Protein-tyrosine kinase receptor flk-1; CD309; VEGFR2 | |||||
| 201348 | Vimentin | 201348 | P08670 |