High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 949 | 842 | | 9889 | 31538 | 604.3 | 116.89 | 203.51 | 321.81 | 475 | 511 | 538 | 562 | 585 | 611 | 645 | 691 | 761 | 0.0383 | 1208 | 0.571 | 106.00 | 25.06 | 1 | 0.0342 | 338 | 0.0006 | 73.38 | 7.682 | 0.1588 | 378894.0 | 247000000 | 168000000000 | 119000000000000 | 0.4171 | 0.2369 | 0.0003 | 0.0000 | 0.0004 | 0.0000 | 0.0019 | 0.0004 | 0.0074 | 0.0013 | 0.0446 | 0.0124 | 0.0828 | 0.0265 | 0.0975 | 0.0233 | 0.1253 | 0.0331 | 0.6398 | 0.9031 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0005 | 0.0001 | 0.0032 | 0.0003 | 0.0237 | 0.0085 | 0.0410 | 0.0170 | 0.0490 | 0.0098 | 0.0664 | 0.0157 | 0.8162 | 0.9485 | 0.0014 | 0.0049 | 0.0084 | 0.0172 | 0.0274 | 0.0197 | 0.0556 | 0.1032 | 0.0985 | 0.1106 | 0.1343 | 0.1548 | 0.1069 | 0.1253 | 0.1153 | 0.1327 | 0.4522 | 0.3317 | 0.0012 | 0.0036 | 0.0092 | 0.0412 | 0.0736 | 0.1091 | 0.0992 | 0.1165 | 0.5465 | 8 | 9 | 12 | 17 | 48 | 103 | 192 | 355 | 647 | 0.1118 | 47.39 | 5.112 | 0.5378 | 144975.0 | 152000000 | 200000000000 | 309000000000000 | 0.3985 | 0.2132 | 0.0695 | 0.0027 | 0.2144 | 0.0263 | 0.2470 | 0.1596 | 0.1348 | 0.1210 | 0.1242 | 0.1636 | 0.0801 | 0.1770 | 0.0595 | 0.1103 | 0.0374 | 0.0928 | 0.0331 | 0.1466 | 0.0000 | 0.0001 | 0.0006 | 0.0005 | 0.0010 | 0.0014 | 0.0081 | 0.0074 | 0.0606 | 0.0447 | 0.0939 | 0.0785 | 0.0610 | 0.0514 | 0.0947 | 0.0842 | 0.6801 | 0.7319 | 0.0001 | 0.0003 | 0.0006 | 0.0005 | 0.0012 | 0.0012 | 0.0163 | 0.0192 | 0.0766 | 0.0837 | 0.1158 | 0.1356 | 0.0765 | 0.0760 | 0.1122 | 0.1199 | 0.6007 | 0.5636 | 0.0002 | 0.0005 | 0.0013 | 0.0122 | 0.0687 | 0.1051 | 0.0681 | 0.1068 | 0.6370 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 420 | 742 | | 10935 | 36965 | 570.5 | 116.52 | 204.39 | 357.85 | 434 | 472 | 502 | 530 | 557 | 586 | 619 | 663 | 727 | 0.0445 | 1646 | 1.010 | 102.55 | 38.05 | 2 | 0.0258 | 282 | 0.0006 | 81.76 | 7.769 | 0.1488 | 339006.0 | 210000000 | 136000000000 | 92000000000000 | 0.4191 | 0.2288 | 0.0003 | 0.0000 | 0.0004 | 0.0000 | 0.0035 | 0.0003 | 0.0113 | 0.0011 | 0.0543 | 0.0126 | 0.1116 | 0.0285 | 0.1155 | 0.0282 | 0.1447 | 0.0456 | 0.5584 | 0.8837 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0011 | 0.0000 | 0.0039 | 0.0003 | 0.0256 | 0.0086 | 0.0516 | 0.0165 | 0.0554 | 0.0121 | 0.0712 | 0.0199 | 0.7907 | 0.9426 | 0.0034 | 0.0123 | 0.0069 | 0.0369 | 0.0195 | 0.0541 | 0.0653 | 0.1253 | 0.1146 | 0.1695 | 0.1725 | 0.1892 | 0.1135 | 0.0983 | 0.1358 | 0.1007 | 0.3685 | 0.2138 | 0.0006 | 0.0044 | 0.0105 | 0.0277 | 0.0720 | 0.1148 | 0.0938 | 0.1191 | 0.5571 | 6 | 8 | 9 | 11 | 14 | 35 | 134 | 381 | 754 | 0.1781 | 65.60 | 4.468 | 0.5873 | 169829.0 | 188000000 | 243000000000 | 352000000000000 | 0.4094 | 0.2312 | 0.1194 | 0.0037 | 0.3132 | 0.0514 | 0.3248 | 0.2365 | 0.1171 | 0.2139 | 0.0620 | 0.1913 | 0.0302 | 0.1403 | 0.0225 | 0.0740 | 0.0078 | 0.0503 | 0.0031 | 0.0385 | 0.0000 | 0.0000 | 0.0001 | 0.0002 | 0.0004 | 0.0009 | 0.0066 | 0.0033 | 0.0399 | 0.0364 | 0.0767 | 0.0693 | 0.0521 | 0.0427 | 0.0787 | 0.0708 | 0.7456 | 0.7764 | 0.0000 | 0.0000 | 0.0001 | 0.0003 | 0.0010 | 0.0015 | 0.0075 | 0.0101 | 0.0502 | 0.0538 | 0.0946 | 0.1037 | 0.0644 | 0.0702 | 0.0978 | 0.1071 | 0.6844 | 0.6533 | 0.0000 | 0.0002 | 0.0006 | 0.0068 | 0.0462 | 0.0827 | 0.0597 | 0.0911 | 0.7127 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 937 | 792 | | 9123 | 21746 | 335.0 | 60.34 | 75.58 | 106.02 | 251 | 283 | 304 | 322 | 338 | 352 | 368 | 385 | 407 | 0.0469 | 1020 | 1.203 | 88.96 | 31.32 | 2 | 0.0240 | 219 | 0.0031 | 5.79 | 6.087 | 0.3990 | 115860.0 | 41200000 | 15100000000 | 5640000000000 | 0.3775 | 0.2592 | 0.0006 | 0.0000 | 0.0019 | 0.0001 | 0.0030 | 0.0007 | 0.0099 | 0.0012 | 0.0231 | 0.0099 | 0.0367 | 0.0248 | 0.0410 | 0.0160 | 0.0611 | 0.0234 | 0.8226 | 0.9239 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0010 | 0.0003 | 0.0037 | 0.0008 | 0.0116 | 0.0086 | 0.0156 | 0.0195 | 0.0156 | 0.0089 | 0.0230 | 0.0132 | 0.9290 | 0.9487 | 0.0127 | 0.0397 | 0.0136 | 0.0397 | 0.0363 | 0.1429 | 0.0417 | 0.1190 | 0.0644 | 0.1587 | 0.0816 | 0.1905 | 0.0743 | 0.0635 | 0.0988 | 0.0952 | 0.5766 | 0.1508 | 0.0021 | 0.0040 | 0.0109 | 0.0129 | 0.0253 | 0.0322 | 0.0430 | 0.0670 | 0.8026 | 6 | 7 | 9 | 13 | 26 | 46 | 79 | 134 | 219 | 0.0597 | 7.19 | 4.039 | 0.5263 | 16952.4 | 5760000 | 2510000000 | 1300000000000 | 0.3182 | 0.3239 | 0.0564 | 0.0038 | 0.1472 | 0.0263 | 0.2620 | 0.0928 | 0.1675 | 0.1276 | 0.1368 | 0.1702 | 0.0969 | 0.1688 | 0.0595 | 0.1401 | 0.0485 | 0.1159 | 0.0252 | 0.1545 | 0.0001 | 0.0005 | 0.0012 | 0.0006 | 0.0032 | 0.0031 | 0.0151 | 0.0112 | 0.0474 | 0.0451 | 0.0827 | 0.0582 | 0.0582 | 0.0542 | 0.0838 | 0.0756 | 0.7083 | 0.7517 | 0.0012 | 0.0002 | 0.0012 | 0.0019 | 0.0027 | 0.0043 | 0.0211 | 0.0249 | 0.0642 | 0.0784 | 0.1127 | 0.1071 | 0.0701 | 0.0779 | 0.0991 | 0.1155 | 0.6278 | 0.5898 | 0.0006 | 0.0010 | 0.0024 | 0.0164 | 0.0621 | 0.0942 | 0.0691 | 0.0956 | 0.6587 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 199 | 260 | | 10686 | 24087 | 343.1 | 42.34 | 218.62 | 243.80 | 294 | 309 | 319 | 329 | 339 | 349 | 361 | 376 | 398 | 0.0560 | 1348 | 1.108 | 80.65 | 27.02 | 2 | 0.0188 | 201 | 0.0020 | 20.94 | 6.553 | 0.2495 | 119532.0 | 42300000 | 15200000000 | 5550000000000 | 0.4430 | 0.2105 | 0.0001 | 0.0000 | 0.0002 | 0.0000 | 0.0012 | 0.0000 | 0.0032 | 0.0005 | 0.0194 | 0.0089 | 0.0355 | 0.0176 | 0.0461 | 0.0113 | 0.0755 | 0.0211 | 0.8188 | 0.9407 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0015 | 0.0000 | 0.0114 | 0.0086 | 0.0212 | 0.0159 | 0.0232 | 0.0077 | 0.0352 | 0.0146 | 0.9074 | 0.9532 | 0.0199 | 0.0000 | 0.0385 | 0.0000 | 0.0442 | 0.0000 | 0.0855 | 0.0000 | 0.0954 | 0.0000 | 0.1311 | 0.0000 | 0.1197 | 0.0000 | 0.1211 | 0.0000 | 0.3447 | 0.0000 | 0.0047 | 0.0098 | 0.0155 | 0.0422 | 0.0674 | 0.0986 | 0.1131 | 0.1277 | 0.5211 | 18 | 23 | 29 | 46 | 110 | 198 | 297 | 422 | 589 | 0.0307 | 46.12 | 5.951 | 0.4302 | 107227.0 | 68300000 | 50200000000 | 40800000000000 | 0.5298 | 0.1259 | 0.0245 | 0.0018 | 0.1127 | 0.0149 | 0.2277 | 0.0610 | 0.1750 | 0.0972 | 0.1550 | 0.1809 | 0.1245 | 0.2068 | 0.0732 | 0.1277 | 0.0609 | 0.1204 | 0.0464 | 0.1894 | 0.0000 | 0.0000 | 0.0005 | 0.0002 | 0.0017 | 0.0016 | 0.0077 | 0.0073 | 0.0415 | 0.0338 | 0.0707 | 0.0588 | 0.0495 | 0.0417 | 0.0772 | 0.0625 | 0.7513 | 0.7941 | 0.0004 | 0.0004 | 0.0010 | 0.0016 | 0.0029 | 0.0041 | 0.0139 | 0.0205 | 0.0578 | 0.0653 | 0.0903 | 0.1105 | 0.0763 | 0.0890 | 0.1087 | 0.1110 | 0.6487 | 0.5975 | 0.0001 | 0.0011 | 0.0034 | 0.0105 | 0.0471 | 0.0826 | 0.0615 | 0.0887 | 0.7050 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 425 | 155 | | 10526 | 21020 | 318.4 | 61.96 | 206.32 | 250.19 | 242 | 266 | 284 | 299 | 314 | 330 | 347 | 369 | 404 | 0.0516 | 1084 | 1.093 | 105.19 | 36.12 | 1 | 0.0249 | 262 | 0.0006 | 81.62 | 7.746 | 0.1363 | 105224.0 | 36000000 | 12800000000 | 4660000000000 | 0.4431 | 0.2108 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0026 | 0.0000 | 0.0134 | 0.0015 | 0.0534 | 0.0127 | 0.1190 | 0.0291 | 0.1293 | 0.0329 | 0.1742 | 0.0536 | 0.5079 | 0.8701 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0007 | 0.0233 | 0.0087 | 0.0553 | 0.0181 | 0.0559 | 0.0145 | 0.0879 | 0.0257 | 0.7716 | 0.9324 | 0.0047 | 0.0280 | 0.0142 | 0.0592 | 0.0272 | 0.0592 | 0.0781 | 0.1526 | 0.1230 | 0.2087 | 0.1715 | 0.2150 | 0.1212 | 0.1277 | 0.1467 | 0.0779 | 0.3134 | 0.0717 | 0.0012 | 0.0020 | 0.0075 | 0.0315 | 0.0817 | 0.1365 | 0.1121 | 0.1303 | 0.4971 | 16 | 20 | 26 | 45 | 90 | 165 | 257 | 379 | 569 | 0.0265 | 51.36 | 6.104 | 0.4177 | 105162.0 | 74300000 | 63500000000 | 62100000000000 | 0.4677 | 0.1545 | 0.0348 | 0.0018 | 0.1515 | 0.0098 | 0.2413 | 0.0665 | 0.1600 | 0.1355 | 0.1658 | 0.1909 | 0.1109 | 0.1899 | 0.0702 | 0.1368 | 0.0428 | 0.1209 | 0.0227 | 0.1479 | 0.0001 | 0.0002 | 0.0006 | 0.0006 | 0.0021 | 0.0007 | 0.0075 | 0.0067 | 0.0513 | 0.0425 | 0.0842 | 0.0699 | 0.0615 | 0.0534 | 0.0927 | 0.0778 | 0.7001 | 0.7481 | 0.0000 | 0.0002 | 0.0017 | 0.0024 | 0.0040 | 0.0065 | 0.0161 | 0.0168 | 0.0672 | 0.0746 | 0.1113 | 0.1207 | 0.0727 | 0.0793 | 0.1113 | 0.1116 | 0.6157 | 0.5879 | 0.0003 | 0.0009 | 0.0029 | 0.0128 | 0.0565 | 0.0983 | 0.0684 | 0.1010 | 0.6588 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1044 | 317 | | 12277 | 27737 | 337.8 | 80.82 | 126.25 | 196.68 | 245 | 268 | 287 | 306 | 326 | 349 | 374 | 406 | 447 | 0.0408 | 1133 | 1.055 | 137.89 | 53.26 | 1 | 0.0307 | 377 | 0.0011 | 31.32 | 7.089 | 0.2146 | 120627.0 | 45500000 | 18100000000 | 7610000000000 | 0.4436 | 0.2108 | 0.0003 | 0.0000 | 0.0014 | 0.0000 | 0.0075 | 0.0005 | 0.0193 | 0.0028 | 0.0768 | 0.0156 | 0.1399 | 0.0382 | 0.1395 | 0.0401 | 0.1655 | 0.0606 | 0.4499 | 0.8421 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0021 | 0.0000 | 0.0066 | 0.0003 | 0.0331 | 0.0088 | 0.0616 | 0.0201 | 0.0593 | 0.0159 | 0.0849 | 0.0256 | 0.7518 | 0.9293 | 0.0008 | 0.0082 | 0.0036 | 0.0192 | 0.0097 | 0.0549 | 0.0449 | 0.1152 | 0.1237 | 0.1578 | 0.1556 | 0.1852 | 0.1144 | 0.1221 | 0.1516 | 0.1221 | 0.3957 | 0.2154 | 0.0007 | 0.0024 | 0.0049 | 0.0284 | 0.0649 | 0.1105 | 0.0822 | 0.1107 | 0.5952 | 5 | 7 | 8 | 10 | 13 | 46 | 142 | 252 | 404 | 0.0900 | 13.02 | 4.139 | 0.4903 | 54618.6 | 33500000 | 26000000000 | 23800000000000 | 0.3964 | 0.2554 | 0.0519 | 0.0030 | 0.2024 | 0.0144 | 0.3281 | 0.0926 | 0.1490 | 0.1590 | 0.1211 | 0.2328 | 0.0760 | 0.2176 | 0.0384 | 0.1206 | 0.0256 | 0.0893 | 0.0075 | 0.0708 | 0.0000 | 0.0000 | 0.0002 | 0.0003 | 0.0009 | 0.0006 | 0.0045 | 0.0028 | 0.0333 | 0.0259 | 0.0610 | 0.0514 | 0.0479 | 0.0383 | 0.0731 | 0.0617 | 0.7792 | 0.8190 | 0.0002 | 0.0001 | 0.0001 | 0.0012 | 0.0011 | 0.0016 | 0.0074 | 0.0108 | 0.0452 | 0.0500 | 0.0802 | 0.0994 | 0.0683 | 0.0688 | 0.0954 | 0.1041 | 0.7019 | 0.6639 | 0.0001 | 0.0001 | 0.0005 | 0.0061 | 0.0373 | 0.0712 | 0.0564 | 0.0847 | 0.7437 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1060 | 148 | | 9173 | 22344 | 294.9 | 54.87 | 142.27 | 167.42 | 227 | 246 | 262 | 276 | 290 | 304 | 321 | 343 | 371 | 0.0689 | 1540 | 0.872 | 128.71 | 44.38 | 1 | 0.0395 | 362 | 0.0007 | 53.70 | 7.461 | 0.1589 | 89976.7 | 28400000 | 9240000000 | 3100000000000 | 0.4189 | 0.2273 | 0.0002 | 0.0000 | 0.0012 | 0.0000 | 0.0039 | 0.0000 | 0.0119 | 0.0010 | 0.0544 | 0.0105 | 0.1011 | 0.0239 | 0.1296 | 0.0218 | 0.1648 | 0.0345 | 0.5330 | 0.9084 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0059 | 0.0002 | 0.0246 | 0.0088 | 0.0420 | 0.0180 | 0.0587 | 0.0104 | 0.0811 | 0.0154 | 0.7860 | 0.9472 | 0.0035 | 0.0359 | 0.0110 | 0.0256 | 0.0311 | 0.0769 | 0.0876 | 0.1487 | 0.1090 | 0.1436 | 0.1739 | 0.1641 | 0.1256 | 0.1128 | 0.1387 | 0.1231 | 0.3195 | 0.1692 | 0.0012 | 0.0047 | 0.0077 | 0.0323 | 0.0798 | 0.1131 | 0.0949 | 0.1254 | 0.5411 | 14 | 17 | 22 | 39 | 72 | 114 | 176 | 260 | 379 | 0.0282 | 29.29 | 5.688 | 0.4480 | 48267.7 | 23800000 | 15100000000 | 12000000000000 | 0.5526 | 0.1273 | 0.0495 | 0.0023 | 0.1676 | 0.0182 | 0.2382 | 0.0872 | 0.1820 | 0.1262 | 0.1201 | 0.1819 | 0.1042 | 0.1777 | 0.0735 | 0.1315 | 0.0360 | 0.1131 | 0.0288 | 0.1618 | 0.0010 | 0.0004 | 0.0013 | 0.0008 | 0.0025 | 0.0027 | 0.0122 | 0.0114 | 0.0574 | 0.0459 | 0.1001 | 0.0810 | 0.0689 | 0.0643 | 0.0971 | 0.0872 | 0.6595 | 0.7063 | 0.0003 | 0.0003 | 0.0007 | 0.0013 | 0.0044 | 0.0053 | 0.0173 | 0.0217 | 0.0820 | 0.0881 | 0.1194 | 0.1360 | 0.0834 | 0.0891 | 0.1164 | 0.1154 | 0.5761 | 0.5428 | 0.0005 | 0.0013 | 0.0029 | 0.0153 | 0.0705 | 0.1085 | 0.0767 | 0.1091 | 0.6152 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 621 | 832 | | 10045 | 16653 | 624.4 | 136.14 | 146.38 | 247.89 | 478 | 513 | 544 | 571 | 595 | 625 | 662 | 712 | 830 | 0.0671 | 1118 | 1.208 | 132.46 | 56.89 | 1 | 0.0353 | 355 | 0.0011 | 29.04 | 7.171 | 0.2381 | 408412.0 | 281000000 | 204000000000 | 157000000000000 | 0.4086 | 0.2413 | 0.0006 | 0.0000 | 0.0012 | 0.0000 | 0.0023 | 0.0007 | 0.0125 | 0.0016 | 0.0328 | 0.0154 | 0.0584 | 0.0291 | 0.0670 | 0.0221 | 0.0956 | 0.0345 | 0.7297 | 0.8966 | 0.0005 | 0.0000 | 0.0006 | 0.0000 | 0.0014 | 0.0000 | 0.0072 | 0.0002 | 0.0161 | 0.0088 | 0.0293 | 0.0152 | 0.0349 | 0.0084 | 0.0505 | 0.0148 | 0.8595 | 0.9526 | 0.0006 | 0.0029 | 0.0069 | 0.0073 | 0.0075 | 0.0190 | 0.0162 | 0.0321 | 0.0643 | 0.1226 | 0.0899 | 0.1431 | 0.0762 | 0.1080 | 0.1043 | 0.1328 | 0.6340 | 0.4321 | 0.0025 | 0.0025 | 0.0069 | 0.0195 | 0.0468 | 0.0683 | 0.0678 | 0.0849 | 0.7009 | 4 | 5 | 6 | 8 | 10 | 19 | 116 | 297 | 537 | 0.1488 | 72.06 | 4.406 | 0.5290 | 82870.7 | 61800000 | 54900000000 | 56100000000000 | 0.4135 | 0.2138 | 0.0751 | 0.0057 | 0.2521 | 0.0378 | 0.2654 | 0.1946 | 0.1669 | 0.1626 | 0.1135 | 0.1847 | 0.0785 | 0.1782 | 0.0234 | 0.1043 | 0.0200 | 0.0796 | 0.0050 | 0.0525 | 0.0000 | 0.0004 | 0.0008 | 0.0011 | 0.0014 | 0.0009 | 0.0050 | 0.0058 | 0.0321 | 0.0227 | 0.0675 | 0.0676 | 0.0431 | 0.0353 | 0.0673 | 0.0584 | 0.7827 | 0.8076 | 0.0009 | 0.0002 | 0.0005 | 0.0005 | 0.0023 | 0.0017 | 0.0068 | 0.0076 | 0.0390 | 0.0463 | 0.0847 | 0.0926 | 0.0513 | 0.0638 | 0.0884 | 0.0938 | 0.7262 | 0.6935 | 0.0000 | 0.0006 | 0.0023 | 0.0088 | 0.0301 | 0.0818 | 0.0496 | 0.0716 | 0.7552 | ||
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 459 | 658 | | 11362 | 20851 | 286.6 | 57.22 | 160.43 | 166.77 | 216 | 238 | 254 | 268 | 283 | 297 | 315 | 335 | 362 | 0.0609 | 1269 | 1.250 | 84.58 | 36.89 | 1 | 0.0202 | 229 | 0.0006 | 69.33 | 7.619 | 0.1453 | 85435.4 | 26400000 | 8470000000 | 2810000000000 | 0.3998 | 0.2496 | 0.0001 | 0.0000 | 0.0008 | 0.0000 | 0.0026 | 0.0000 | 0.0151 | 0.0008 | 0.0564 | 0.0119 | 0.1324 | 0.0353 | 0.1449 | 0.0348 | 0.1680 | 0.0534 | 0.4798 | 0.8638 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0011 | 0.0000 | 0.0057 | 0.0004 | 0.0244 | 0.0088 | 0.0561 | 0.0236 | 0.0596 | 0.0148 | 0.0768 | 0.0231 | 0.7756 | 0.9293 | 0.0061 | 0.0143 | 0.0094 | 0.0544 | 0.0304 | 0.0716 | 0.0839 | 0.1777 | 0.1733 | 0.2521 | 0.1926 | 0.1519 | 0.1291 | 0.0917 | 0.1512 | 0.0974 | 0.2241 | 0.0888 | 0.0015 | 0.0022 | 0.0078 | 0.0347 | 0.0806 | 0.1342 | 0.1129 | 0.1362 | 0.4899 | 14 | 18 | 28 | 51 | 95 | 156 | 222 | 299 | 405 | 0.0196 | 36.84 | 6.010 | 0.3723 | 53550.1 | 23300000 | 11800000000 | 6650000000000 | 0.5064 | 0.1481 | 0.0625 | 0.0012 | 0.2600 | 0.0157 | 0.3022 | 0.1503 | 0.1409 | 0.1993 | 0.0988 | 0.2074 | 0.0736 | 0.1703 | 0.0334 | 0.0942 | 0.0252 | 0.0818 | 0.0034 | 0.0799 | 0.0001 | 0.0000 | 0.0004 | 0.0005 | 0.0019 | 0.0015 | 0.0115 | 0.0099 | 0.0600 | 0.0532 | 0.1157 | 0.0968 | 0.0747 | 0.0636 | 0.1141 | 0.0984 | 0.6214 | 0.6761 | 0.0004 | 0.0010 | 0.0028 | 0.0037 | 0.0065 | 0.0110 | 0.0223 | 0.0260 | 0.0761 | 0.0864 | 0.1468 | 0.1528 | 0.0956 | 0.1004 | 0.1209 | 0.1293 | 0.5286 | 0.4895 | 0.0000 | 0.0010 | 0.0039 | 0.0157 | 0.0717 | 0.1279 | 0.0896 | 0.1188 | 0.5713 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 767 | 375 | | 10994 | 36702 | 317.2 | 66.33 | 88.78 | 117.60 | 238 | 259 | 276 | 292 | 309 | 327 | 346 | 373 | 410 | 0.0385 | 1412 | 0.777 | 113.02 | 23.02 | 1 | 0.0226 | 249 | 0.0006 | 70.27 | 7.726 | 0.1479 | 104984.0 | 36300000 | 13000000000 | 4880000000000 | 0.4228 | 0.2250 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0038 | 0.0001 | 0.0125 | 0.0008 | 0.0612 | 0.0134 | 0.1259 | 0.0305 | 0.1295 | 0.0324 | 0.1666 | 0.0567 | 0.4994 | 0.8660 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0021 | 0.0000 | 0.0062 | 0.0003 | 0.0265 | 0.0088 | 0.0510 | 0.0177 | 0.0541 | 0.0124 | 0.0766 | 0.0239 | 0.7828 | 0.9370 | 0.0031 | 0.0102 | 0.0078 | 0.0225 | 0.0225 | 0.0758 | 0.0628 | 0.1250 | 0.1313 | 0.1557 | 0.1763 | 0.1475 | 0.1104 | 0.1025 | 0.1423 | 0.1270 | 0.3433 | 0.2336 | 0.0010 | 0.0030 | 0.0062 | 0.0294 | 0.0726 | 0.1184 | 0.1031 | 0.1345 | 0.5318 | 10 | 12 | 14 | 19 | 32 | 55 | 97 | 156 | 255 | 0.0788 | 13.52 | 4.639 | 0.5538 | 21712.5 | 8010000 | 3800000000 | 2180000000000 | 0.4103 | 0.2154 | 0.0637 | 0.0009 | 0.2390 | 0.0098 | 0.3525 | 0.1068 | 0.1643 | 0.1924 | 0.0959 | 0.2534 | 0.0480 | 0.2004 | 0.0216 | 0.1040 | 0.0113 | 0.0742 | 0.0037 | 0.0580 | 0.0002 | 0.0001 | 0.0002 | 0.0004 | 0.0009 | 0.0012 | 0.0109 | 0.0097 | 0.0639 | 0.0507 | 0.0964 | 0.0843 | 0.0715 | 0.0616 | 0.1087 | 0.0931 | 0.6473 | 0.6989 | 0.0002 | 0.0004 | 0.0011 | 0.0016 | 0.0034 | 0.0043 | 0.0175 | 0.0189 | 0.0814 | 0.0927 | 0.1222 | 0.1338 | 0.0853 | 0.0887 | 0.1273 | 0.1253 | 0.5616 | 0.5343 | 0.0001 | 0.0004 | 0.0016 | 0.0110 | 0.0724 | 0.1147 | 0.0774 | 0.1169 | 0.6055 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 802 | 490 | | 8351 | 22610 | 575.7 | 122.92 | 67.00 | 140.53 | 447 | 481 | 507 | 530 | 554 | 578 | 610 | 654 | 726 | 0.0503 | 1138 | 0.892 | 99.02 | 25.02 | 1 | 0.0290 | 242 | 0.0006 | 85.09 | 7.659 | 0.1388 | 346489.0 | 219000000 | 147000000000 | 104000000000000 | 0.4366 | 0.2123 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0016 | 0.0000 | 0.0107 | 0.0008 | 0.0464 | 0.0130 | 0.0968 | 0.0349 | 0.1084 | 0.0240 | 0.1476 | 0.0372 | 0.5879 | 0.8901 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0006 | 0.0000 | 0.0054 | 0.0000 | 0.0254 | 0.0090 | 0.0547 | 0.0192 | 0.0514 | 0.0107 | 0.0823 | 0.0199 | 0.7799 | 0.9412 | 0.0017 | 0.0022 | 0.0111 | 0.0066 | 0.0085 | 0.0087 | 0.0752 | 0.0502 | 0.1265 | 0.1397 | 0.1282 | 0.1790 | 0.0966 | 0.0830 | 0.1154 | 0.1397 | 0.4368 | 0.3908 | 0.0018 | 0.0062 | 0.0117 | 0.0486 | 0.0847 | 0.1260 | 0.0923 | 0.1116 | 0.5173 | 5 | 6 | 7 | 8 | 9 | 11 | 17 | 73 | 234 | 0.2107 | 10.92 | 3.086 | 0.6429 | 24238.2 | 13000000 | 8460000000 | 6260000000000 | 0.4231 | 0.2043 | 0.0750 | 0.0052 | 0.2339 | 0.0353 | 0.2519 | 0.1576 | 0.1589 | 0.1532 | 0.1364 | 0.2054 | 0.0885 | 0.1760 | 0.0390 | 0.1105 | 0.0150 | 0.0913 | 0.0015 | 0.0655 | 0.0000 | 0.0002 | 0.0004 | 0.0006 | 0.0016 | 0.0006 | 0.0084 | 0.0107 | 0.0408 | 0.0369 | 0.0753 | 0.0625 | 0.0404 | 0.0411 | 0.0677 | 0.0705 | 0.7654 | 0.7769 | 0.0002 | 0.0000 | 0.0009 | 0.0005 | 0.0016 | 0.0032 | 0.0125 | 0.0133 | 0.0519 | 0.0529 | 0.0775 | 0.0940 | 0.0542 | 0.0529 | 0.0860 | 0.0876 | 0.7152 | 0.6955 | 0.0002 | 0.0013 | 0.0024 | 0.0124 | 0.0425 | 0.0726 | 0.0494 | 0.0774 | 0.7419 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 776 | 533 | | 11980 | 33861 | 383.5 | 82.50 | 120.63 | 176.56 | 283 | 310 | 334 | 355 | 376 | 398 | 421 | 451 | 496 | 0.0356 | 1205 | 1.136 | 140.66 | 55.15 | 1 | 0.0313 | 375 | 0.0009 | 37.01 | 7.234 | 0.1929 | 153867.0 | 64500000 | 28200000000 | 12800000000000 | 0.4493 | 0.2003 | 0.0001 | 0.0000 | 0.0008 | 0.0000 | 0.0028 | 0.0000 | 0.0182 | 0.0008 | 0.0630 | 0.0134 | 0.1320 | 0.0320 | 0.1379 | 0.0333 | 0.1599 | 0.0519 | 0.4853 | 0.8686 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0010 | 0.0000 | 0.0076 | 0.0001 | 0.0277 | 0.0090 | 0.0540 | 0.0170 | 0.0581 | 0.0126 | 0.0745 | 0.0212 | 0.7764 | 0.9401 | 0.0019 | 0.0113 | 0.0047 | 0.0244 | 0.0159 | 0.0357 | 0.0637 | 0.1429 | 0.1404 | 0.1560 | 0.1807 | 0.2237 | 0.1147 | 0.0977 | 0.1470 | 0.1278 | 0.3310 | 0.1805 | 0.0004 | 0.0018 | 0.0069 | 0.0208 | 0.0738 | 0.1090 | 0.1005 | 0.1337 | 0.5532 | 7 | 8 | 10 | 13 | 28 | 71 | 135 | 223 | 358 | 0.1025 | 9.69 | 4.335 | 0.5557 | 45723.5 | 25300000 | 17600000000 | 14200000000000 | 0.3892 | 0.2409 | 0.0580 | 0.0013 | 0.2129 | 0.0223 | 0.2772 | 0.1129 | 0.1731 | 0.1468 | 0.1215 | 0.2079 | 0.0876 | 0.1983 | 0.0398 | 0.1203 | 0.0207 | 0.0982 | 0.0093 | 0.0921 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0008 | 0.0004 | 0.0071 | 0.0056 | 0.0520 | 0.0410 | 0.0868 | 0.0707 | 0.0678 | 0.0584 | 0.0917 | 0.0804 | 0.6937 | 0.7434 | 0.0005 | 0.0002 | 0.0012 | 0.0009 | 0.0018 | 0.0021 | 0.0154 | 0.0152 | 0.0663 | 0.0760 | 0.1097 | 0.1251 | 0.0819 | 0.0859 | 0.1104 | 0.1159 | 0.6128 | 0.5786 | 0.0001 | 0.0003 | 0.0013 | 0.0107 | 0.0581 | 0.1011 | 0.0739 | 0.1012 | 0.6533 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 686 | 625 | | 6653 | 21616 | 335.3 | 63.66 | 169.19 | 212.41 | 264 | 281 | 295 | 309 | 325 | 342 | 362 | 385 | 425 | 0.0403 | 871 | 1.098 | 108.24 | 36.69 | 1 | 0.0412 | 274 | 0.0007 | 66.56 | 7.535 | 0.1518 | 116505.0 | 42000000 | 15700000000 | 6090000000000 | 0.4550 | 0.1972 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0023 | 0.0002 | 0.0068 | 0.0011 | 0.0474 | 0.0135 | 0.1064 | 0.0297 | 0.1104 | 0.0278 | 0.1437 | 0.0363 | 0.5825 | 0.8914 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0029 | 0.0000 | 0.0239 | 0.0090 | 0.0529 | 0.0155 | 0.0543 | 0.0084 | 0.0731 | 0.0141 | 0.7917 | 0.9529 | 0.0030 | 0.0000 | 0.0120 | 0.0243 | 0.0200 | 0.0208 | 0.0430 | 0.1250 | 0.1289 | 0.1736 | 0.1548 | 0.2153 | 0.1009 | 0.1215 | 0.1419 | 0.1458 | 0.3956 | 0.1736 | 0.0017 | 0.0010 | 0.0113 | 0.0284 | 0.0825 | 0.1140 | 0.1062 | 0.1308 | 0.5240 | 11 | 13 | 15 | 21 | 59 | 135 | 223 | 332 | 480 | 0.0461 | 55.65 | 5.697 | 0.4308 | 73741.6 | 43100000 | 29900000000 | 23400000000000 | 0.4089 | 0.2338 | 0.0463 | 0.0015 | 0.1935 | 0.0167 | 0.2745 | 0.1152 | 0.1777 | 0.1388 | 0.1357 | 0.1962 | 0.0901 | 0.1912 | 0.0542 | 0.1307 | 0.0213 | 0.1096 | 0.0067 | 0.1001 | 0.0001 | 0.0001 | 0.0014 | 0.0005 | 0.0035 | 0.0017 | 0.0088 | 0.0064 | 0.0446 | 0.0382 | 0.0850 | 0.0684 | 0.0604 | 0.0514 | 0.0846 | 0.0704 | 0.7116 | 0.7629 | 0.0009 | 0.0006 | 0.0029 | 0.0029 | 0.0063 | 0.0060 | 0.0129 | 0.0147 | 0.0599 | 0.0658 | 0.1035 | 0.1203 | 0.0786 | 0.0886 | 0.1056 | 0.1095 | 0.6295 | 0.5914 | 0.0001 | 0.0022 | 0.0036 | 0.0127 | 0.0496 | 0.0976 | 0.0729 | 0.0936 | 0.6678 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 552 | 584 | | 9730 | 22960 | 539.9 | 116.17 | 146.55 | 125.01 | 407 | 442 | 468 | 494 | 522 | 550 | 584 | 629 | 705 | 0.0487 | 1118 | 1.101 | 111.89 | 44.42 | 1 | 0.0312 | 304 | 0.0009 | 44.66 | 7.368 | 0.1782 | 304940.0 | 180000000 | 112000000000 | 72500000000000 | 0.4444 | 0.1987 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0022 | 0.0000 | 0.0102 | 0.0014 | 0.0583 | 0.0160 | 0.1054 | 0.0336 | 0.1103 | 0.0294 | 0.1389 | 0.0462 | 0.5744 | 0.8733 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0010 | 0.0000 | 0.0048 | 0.0000 | 0.0270 | 0.0090 | 0.0515 | 0.0177 | 0.0520 | 0.0107 | 0.0667 | 0.0200 | 0.7970 | 0.9425 | 0.0006 | 0.0034 | 0.0104 | 0.0068 | 0.0097 | 0.0273 | 0.0420 | 0.0528 | 0.0981 | 0.1772 | 0.1510 | 0.1772 | 0.1139 | 0.1244 | 0.1364 | 0.1516 | 0.4379 | 0.2794 | 0.0009 | 0.0038 | 0.0081 | 0.0268 | 0.0648 | 0.0997 | 0.0955 | 0.1138 | 0.5866 | 26 | 46 | 69 | 93 | 116 | 141 | 173 | 217 | 307 | 0.0087 | 14.33 | 5.634 | 0.4373 | 37104.1 | 13800000 | 6720000000 | 4000000000000 | 0.5360 | 0.1367 | 0.0163 | 0.0005 | 0.0637 | 0.0048 | 0.1580 | 0.0328 | 0.1548 | 0.0671 | 0.1728 | 0.1313 | 0.1646 | 0.1718 | 0.1121 | 0.1434 | 0.0945 | 0.1555 | 0.0632 | 0.2927 | 0.0004 | 0.0002 | 0.0009 | 0.0007 | 0.0048 | 0.0016 | 0.0166 | 0.0115 | 0.0663 | 0.0489 | 0.1136 | 0.0904 | 0.0895 | 0.0739 | 0.1218 | 0.1031 | 0.5861 | 0.6696 | 0.0010 | 0.0037 | 0.0046 | 0.0085 | 0.0097 | 0.0132 | 0.0331 | 0.0351 | 0.1031 | 0.1074 | 0.1483 | 0.1604 | 0.1084 | 0.1050 | 0.1378 | 0.1369 | 0.4538 | 0.4299 | 0.0014 | 0.0023 | 0.0070 | 0.0228 | 0.0831 | 0.1367 | 0.1048 | 0.1260 | 0.5159 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 673 | 661 | | 8356 | 21692 | 629.4 | 88.97 | 157.77 | 200.04 | 505 | 558 | 588 | 612 | 637 | 660 | 678 | 703 | 736 | 0.0423 | 917 | 1.088 | 108.30 | 37.05 | 1 | 0.0333 | 278 | 0.0009 | 30.54 | 7.337 | 0.2196 | 404042.0 | 264000000 | 175000000000 | 118000000000000 | 0.4222 | 0.2219 | 0.0003 | 0.0000 | 0.0004 | 0.0000 | 0.0007 | 0.0000 | 0.0036 | 0.0002 | 0.0168 | 0.0091 | 0.0339 | 0.0170 | 0.0309 | 0.0087 | 0.0431 | 0.0141 | 0.8703 | 0.9508 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0017 | 0.0002 | 0.0097 | 0.0091 | 0.0211 | 0.0170 | 0.0174 | 0.0087 | 0.0212 | 0.0141 | 0.9286 | 0.9508 | 0.0052 | 0.0000 | 0.0087 | 0.0000 | 0.0280 | 0.0000 | 0.0332 | 0.0000 | 0.0769 | 0.0000 | 0.1206 | 0.0000 | 0.0962 | 0.0000 | 0.1521 | 0.0000 | 0.4790 | 0.0000 | 0.0011 | 0.0031 | 0.0058 | 0.0105 | 0.0285 | 0.0524 | 0.0515 | 0.0731 | 0.7740 | 10 | 13 | 19 | 33 | 63 | 113 | 189 | 289 | 461 | 0.0633 | 29.43 | 5.277 | 0.5302 | 64906.9 | 36700000 | 24600000000 | 18400000000000 | 0.4278 | 0.2001 | 0.0270 | 0.0020 | 0.1224 | 0.0151 | 0.2282 | 0.0660 | 0.1787 | 0.1115 | 0.1483 | 0.1596 | 0.1201 | 0.2156 | 0.0684 | 0.1388 | 0.0615 | 0.1073 | 0.0454 | 0.1841 | 0.0001 | 0.0003 | 0.0002 | 0.0008 | 0.0015 | 0.0014 | 0.0077 | 0.0098 | 0.0437 | 0.0330 | 0.0678 | 0.0540 | 0.0479 | 0.0450 | 0.0793 | 0.0589 | 0.7519 | 0.7967 | 0.0005 | 0.0000 | 0.0015 | 0.0012 | 0.0026 | 0.0031 | 0.0122 | 0.0151 | 0.0611 | 0.0727 | 0.0953 | 0.1124 | 0.0662 | 0.0769 | 0.1035 | 0.1141 | 0.6570 | 0.6045 | 0.0001 | 0.0010 | 0.0024 | 0.0121 | 0.0486 | 0.0835 | 0.0554 | 0.0881 | 0.7087 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1177 | 177 | | 8873 | 27955 | 248.5 | 47.11 | 109.86 | 157.87 | 191 | 208 | 221 | 233 | 244 | 256 | 271 | 287 | 314 | 0.0469 | 1311 | 0.994 | 127.91 | 39.00 | 1 | 0.0355 | 315 | 0.0008 | 53.04 | 7.325 | 0.1590 | 63995.2 | 17100000 | 4700000000 | 1340000000000 | 0.4343 | 0.2173 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0027 | 0.0000 | 0.0120 | 0.0007 | 0.0522 | 0.0127 | 0.1214 | 0.0295 | 0.1345 | 0.0288 | 0.1777 | 0.0558 | 0.4991 | 0.8725 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0046 | 0.0000 | 0.0244 | 0.0092 | 0.0562 | 0.0202 | 0.0603 | 0.0122 | 0.0912 | 0.0247 | 0.7617 | 0.9337 | 0.0052 | 0.0297 | 0.0140 | 0.0890 | 0.0295 | 0.0932 | 0.0820 | 0.1525 | 0.1462 | 0.2288 | 0.1640 | 0.1610 | 0.1248 | 0.0847 | 0.1388 | 0.0890 | 0.2954 | 0.0720 | 0.0024 | 0.0034 | 0.0098 | 0.0396 | 0.0875 | 0.1325 | 0.1151 | 0.1374 | 0.4723 | 8 | 10 | 12 | 14 | 18 | 43 | 118 | 226 | 348 | 0.1117 | 21.16 | 4.563 | 0.5542 | 36992.6 | 17000000 | 9310000000 | 5870000000000 | 0.4998 | 0.1706 | 0.1052 | 0.0037 | 0.2954 | 0.0329 | 0.2884 | 0.1793 | 0.1348 | 0.2009 | 0.0748 | 0.2214 | 0.0639 | 0.1482 | 0.0257 | 0.0933 | 0.0094 | 0.0743 | 0.0023 | 0.0461 | 0.0004 | 0.0000 | 0.0004 | 0.0006 | 0.0015 | 0.0012 | 0.0091 | 0.0073 | 0.0471 | 0.0423 | 0.0840 | 0.0719 | 0.0564 | 0.0505 | 0.0810 | 0.0788 | 0.7201 | 0.7475 | 0.0006 | 0.0005 | 0.0005 | 0.0015 | 0.0017 | 0.0041 | 0.0127 | 0.0145 | 0.0561 | 0.0526 | 0.0904 | 0.1071 | 0.0670 | 0.0757 | 0.1010 | 0.1065 | 0.6698 | 0.6375 | 0.0003 | 0.0003 | 0.0020 | 0.0116 | 0.0481 | 0.0925 | 0.0604 | 0.0911 | 0.6936 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 618 | 706 | | 10617 | 14965 | 406.0 | 74.21 | 106.42 | 146.05 | 301 | 340 | 368 | 390 | 410 | 428 | 446 | 467 | 497 | 0.0708 | 1060 | 1.136 | 84.60 | 28.00 | 1 | 0.0195 | 207 | 0.0009 | 31.67 | 7.285 | 0.2045 | 170377.0 | 73700000 | 32700000000 | 14900000000000 | 0.4237 | 0.2226 | 0.0007 | 0.0000 | 0.0005 | 0.0000 | 0.0022 | 0.0002 | 0.0088 | 0.0007 | 0.0302 | 0.0106 | 0.0672 | 0.0224 | 0.0738 | 0.0182 | 0.1228 | 0.0277 | 0.6938 | 0.9203 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0010 | 0.0001 | 0.0037 | 0.0004 | 0.0152 | 0.0092 | 0.0270 | 0.0175 | 0.0239 | 0.0109 | 0.0406 | 0.0156 | 0.8882 | 0.9463 | 0.0126 | 0.0000 | 0.0223 | 0.0000 | 0.0334 | 0.0000 | 0.0713 | 0.0000 | 0.1166 | 0.0000 | 0.1308 | 0.0000 | 0.1010 | 0.0000 | 0.1337 | 0.0000 | 0.3782 | 0.0000 | 0.0016 | 0.0018 | 0.0038 | 0.0148 | 0.0460 | 0.0748 | 0.0780 | 0.1090 | 0.6702 | 14 | 17 | 21 | 27 | 38 | 57 | 93 | 167 | 327 | 0.0504 | 11.32 | 4.608 | 0.5968 | 32654.3 | 14800000 | 7870000000 | 4610000000000 | 0.5804 | 0.0982 | 0.0354 | 0.0029 | 0.1407 | 0.0100 | 0.2405 | 0.0716 | 0.1506 | 0.1194 | 0.1370 | 0.1573 | 0.0962 | 0.1935 | 0.0762 | 0.1149 | 0.0681 | 0.1036 | 0.0554 | 0.2268 | 0.0006 | 0.0011 | 0.0011 | 0.0011 | 0.0034 | 0.0037 | 0.0120 | 0.0134 | 0.0582 | 0.0461 | 0.0881 | 0.0767 | 0.0586 | 0.0530 | 0.0837 | 0.0788 | 0.6943 | 0.7262 | 0.0000 | 0.0003 | 0.0011 | 0.0012 | 0.0027 | 0.0049 | 0.0165 | 0.0172 | 0.0692 | 0.0712 | 0.1000 | 0.1157 | 0.0744 | 0.0740 | 0.1085 | 0.1074 | 0.6276 | 0.6080 | 0.0005 | 0.0005 | 0.0019 | 0.0150 | 0.0645 | 0.0978 | 0.0619 | 0.1022 | 0.6557 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 959 | 713 | | 6139 | 10848 | 256.2 | 53.54 | 207.18 | 194.13 | 190 | 210 | 225 | 238 | 252 | 266 | 283 | 302 | 326 | 0.0678 | 736 | 1.177 | 102.18 | 37.66 | 1 | 0.0415 | 255 | 0.0008 | 47.93 | 7.299 | 0.1591 | 68517.0 | 19100000 | 5540000000 | 1670000000000 | 0.4834 | 0.1799 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0032 | 0.0003 | 0.0156 | 0.0014 | 0.0740 | 0.0133 | 0.1454 | 0.0377 | 0.1504 | 0.0343 | 0.1835 | 0.0591 | 0.4267 | 0.8538 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0016 | 0.0002 | 0.0059 | 0.0012 | 0.0355 | 0.0092 | 0.0646 | 0.0250 | 0.0616 | 0.0171 | 0.0826 | 0.0290 | 0.7478 | 0.9183 | 0.0067 | 0.0235 | 0.0114 | 0.0141 | 0.0352 | 0.0469 | 0.0856 | 0.1643 | 0.1369 | 0.1925 | 0.1835 | 0.2207 | 0.1274 | 0.0845 | 0.1340 | 0.0986 | 0.2795 | 0.1549 | 0.0024 | 0.0041 | 0.0093 | 0.0368 | 0.0764 | 0.1195 | 0.1012 | 0.1326 | 0.5176 | 19 | 34 | 61 | 103 | 155 | 210 | 274 | 353 | 472 | 0.0078 | 34.55 | 6.449 | 0.3311 | 80606.7 | 42400000 | 27300000000 | 20400000000000 | 0.4122 | 0.2269 | 0.0375 | 0.0010 | 0.1827 | 0.0076 | 0.2438 | 0.0851 | 0.1774 | 0.1506 | 0.1360 | 0.1962 | 0.1064 | 0.2035 | 0.0572 | 0.1157 | 0.0420 | 0.0994 | 0.0171 | 0.1407 | 0.0008 | 0.0002 | 0.0010 | 0.0012 | 0.0031 | 0.0027 | 0.0179 | 0.0119 | 0.0702 | 0.0586 | 0.1159 | 0.1040 | 0.0844 | 0.0695 | 0.1125 | 0.0949 | 0.5943 | 0.6571 | 0.0016 | 0.0020 | 0.0038 | 0.0020 | 0.0071 | 0.0076 | 0.0245 | 0.0311 | 0.0919 | 0.0967 | 0.1321 | 0.1652 | 0.1025 | 0.1119 | 0.1394 | 0.1317 | 0.4971 | 0.4518 | 0.0016 | 0.0016 | 0.0043 | 0.0200 | 0.0832 | 0.1402 | 0.0836 | 0.1216 | 0.5440 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 241 | 848 | | 10173 | 33400 | 558.7 | 106.36 | 141.20 | 210.07 | 440 | 469 | 494 | 517 | 539 | 564 | 595 | 638 | 721 | 0.0340 | 1136 | 1.181 | 125.88 | 48.08 | 1 | 0.0321 | 327 | 0.0010 | 33.71 | 7.169 | 0.1994 | 323447.0 | 194000000 | 121000000000 | 78500000000000 | 0.3999 | 0.2475 | 0.0004 | 0.0002 | 0.0009 | 0.0001 | 0.0027 | 0.0002 | 0.0123 | 0.0021 | 0.0344 | 0.0148 | 0.0701 | 0.0282 | 0.0822 | 0.0219 | 0.1201 | 0.0283 | 0.6769 | 0.9042 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0012 | 0.0000 | 0.0077 | 0.0002 | 0.0193 | 0.0092 | 0.0401 | 0.0151 | 0.0464 | 0.0088 | 0.0651 | 0.0146 | 0.8195 | 0.9521 | 0.0060 | 0.0020 | 0.0079 | 0.0101 | 0.0113 | 0.0061 | 0.0344 | 0.0869 | 0.0656 | 0.1212 | 0.0947 | 0.2222 | 0.0742 | 0.1253 | 0.0947 | 0.1616 | 0.6113 | 0.2646 | 0.0019 | 0.0063 | 0.0137 | 0.0288 | 0.0574 | 0.1020 | 0.0876 | 0.1004 | 0.6019 | 7 | 9 | 12 | 16 | 31 | 71 | 144 | 264 | 446 | 0.0759 | 52.63 | 5.308 | 0.4892 | 64064.9 | 41000000 | 31800000000 | 28400000000000 | 0.3985 | 0.2299 | 0.1332 | 0.0028 | 0.3108 | 0.0481 | 0.2982 | 0.2452 | 0.1039 | 0.2139 | 0.0716 | 0.1845 | 0.0484 | 0.1328 | 0.0222 | 0.0737 | 0.0081 | 0.0576 | 0.0035 | 0.0413 | 0.0002 | 0.0002 | 0.0008 | 0.0002 | 0.0013 | 0.0007 | 0.0107 | 0.0085 | 0.0677 | 0.0583 | 0.1067 | 0.0940 | 0.0684 | 0.0620 | 0.1038 | 0.0989 | 0.6404 | 0.6771 | 0.0001 | 0.0001 | 0.0004 | 0.0005 | 0.0018 | 0.0038 | 0.0161 | 0.0195 | 0.0838 | 0.0907 | 0.1222 | 0.1354 | 0.0813 | 0.0869 | 0.1259 | 0.1305 | 0.5681 | 0.5326 | 0.0003 | 0.0006 | 0.0013 | 0.0134 | 0.0759 | 0.1150 | 0.0717 | 0.1123 | 0.6096 | ||
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 798 | 428 | | 27432 | 45118 | 211.1 | 59.97 | 98.82 | 173.21 | 140 | 162 | 179 | 194 | 208 | 223 | 239 | 258 | 287 | 0.0427 | 1927 | 0.804 | 104.04 | 21.19 | 1 | 0.0082 | 226 | 0.0007 | 43.54 | 7.545 | 0.1862 | 48158.5 | 11800000 | 3050000000 | 838000000000 | 0.4170 | 0.2298 | 0.0009 | 0.0000 | 0.0014 | 0.0001 | 0.0072 | 0.0005 | 0.0254 | 0.0026 | 0.0661 | 0.0188 | 0.1224 | 0.0410 | 0.1361 | 0.0439 | 0.1737 | 0.0674 | 0.4667 | 0.8259 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0027 | 0.0001 | 0.0072 | 0.0009 | 0.0239 | 0.0093 | 0.0448 | 0.0189 | 0.0494 | 0.0177 | 0.0650 | 0.0292 | 0.8061 | 0.9239 | 0.0049 | 0.0049 | 0.0082 | 0.0175 | 0.0196 | 0.0265 | 0.0469 | 0.0746 | 0.0894 | 0.1169 | 0.1266 | 0.1677 | 0.1090 | 0.1102 | 0.1271 | 0.1250 | 0.4683 | 0.3566 | 0.0014 | 0.0023 | 0.0066 | 0.0227 | 0.0535 | 0.0917 | 0.0877 | 0.1135 | 0.6206 | 10 | 12 | 14 | 16 | 20 | 29 | 54 | 137 | 332 | 0.1819 | 23.17 | 3.891 | 0.6587 | 39767.1 | 24100000 | 17400000000 | 14100000000000 | 0.4082 | 0.2647 | 0.1462 | 0.0039 | 0.3078 | 0.0465 | 0.2795 | 0.2378 | 0.1040 | 0.2151 | 0.0818 | 0.2042 | 0.0463 | 0.1441 | 0.0206 | 0.0647 | 0.0093 | 0.0494 | 0.0046 | 0.0343 | 0.0000 | 0.0000 | 0.0009 | 0.0006 | 0.0015 | 0.0011 | 0.0142 | 0.0095 | 0.0704 | 0.0604 | 0.0987 | 0.0930 | 0.0678 | 0.0551 | 0.1104 | 0.0943 | 0.6360 | 0.6860 | 0.0003 | 0.0000 | 0.0017 | 0.0017 | 0.0033 | 0.0043 | 0.0185 | 0.0216 | 0.0848 | 0.0897 | 0.1211 | 0.1251 | 0.0804 | 0.0863 | 0.1188 | 0.1212 | 0.5710 | 0.5502 | 0.0001 | 0.0006 | 0.0030 | 0.0167 | 0.0751 | 0.1185 | 0.0740 | 0.1117 | 0.6002 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 854 | 416 | | 11131 | 15417 | 454.3 | 71.88 | 90.38 | 157.98 | 358 | 393 | 418 | 438 | 454 | 468 | 484 | 508 | 549 | 0.0688 | 1061 | 1.159 | 147.22 | 49.48 | 2 | 0.0314 | 350 | 0.0013 | 17.13 | 6.964 | 0.2615 | 211570.0 | 101000000 | 49300000000 | 24600000000000 | 0.4019 | 0.2435 | 0.0005 | 0.0000 | 0.0012 | 0.0001 | 0.0025 | 0.0005 | 0.0056 | 0.0007 | 0.0198 | 0.0107 | 0.0364 | 0.0188 | 0.0370 | 0.0124 | 0.0542 | 0.0178 | 0.8429 | 0.9388 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0018 | 0.0000 | 0.0023 | 0.0002 | 0.0110 | 0.0093 | 0.0213 | 0.0169 | 0.0198 | 0.0089 | 0.0278 | 0.0138 | 0.9153 | 0.9509 | 0.0058 | 0.0159 | 0.0075 | 0.0397 | 0.0100 | 0.0556 | 0.0325 | 0.1270 | 0.0600 | 0.0873 | 0.0783 | 0.1349 | 0.0666 | 0.1111 | 0.0966 | 0.0952 | 0.6428 | 0.3333 | 0.0012 | 0.0023 | 0.0068 | 0.0178 | 0.0371 | 0.0570 | 0.0697 | 0.0892 | 0.7189 | 7 | 9 | 10 | 11 | 14 | 23 | 53 | 139 | 311 | 0.2296 | 12.11 | 3.590 | 0.7091 | 33126.6 | 17600000 | 11100000000 | 7920000000000 | 0.5835 | 0.1060 | 0.0228 | 0.0066 | 0.0791 | 0.0185 | 0.1263 | 0.0524 | 0.1948 | 0.0739 | 0.1933 | 0.1344 | 0.1522 | 0.1839 | 0.0898 | 0.1440 | 0.0883 | 0.1322 | 0.0533 | 0.2541 | 0.0000 | 0.0006 | 0.0012 | 0.0017 | 0.0021 | 0.0039 | 0.0062 | 0.0067 | 0.0321 | 0.0323 | 0.0482 | 0.0424 | 0.0349 | 0.0336 | 0.0634 | 0.0528 | 0.8120 | 0.8259 | 0.0011 | 0.0003 | 0.0031 | 0.0018 | 0.0025 | 0.0028 | 0.0098 | 0.0104 | 0.0419 | 0.0429 | 0.0613 | 0.0726 | 0.0526 | 0.0643 | 0.0793 | 0.0867 | 0.7482 | 0.7182 | 0.0003 | 0.0013 | 0.0028 | 0.0103 | 0.0339 | 0.0573 | 0.0419 | 0.0637 | 0.7885 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 219 | 287 | | 7728 | 17407 | 156.2 | 33.25 | 151.14 | 137.62 | 117 | 127 | 135 | 144 | 153 | 161 | 171 | 184 | 201 | 0.0567 | 987 | 1.201 | 93.64 | 34.53 | 3 | 0.0299 | 231 | 0.0018 | 24.55 | 6.611 | 0.2248 | 25514.2 | 4360000 | 778000000 | 145000000000 | 0.3633 | 0.2904 | 0.0006 | 0.0000 | 0.0024 | 0.0001 | 0.0054 | 0.0000 | 0.0261 | 0.0015 | 0.0755 | 0.0144 | 0.1309 | 0.0416 | 0.1551 | 0.0359 | 0.1992 | 0.0585 | 0.4049 | 0.8479 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0028 | 0.0000 | 0.0126 | 0.0000 | 0.0327 | 0.0093 | 0.0547 | 0.0253 | 0.0662 | 0.0117 | 0.0973 | 0.0232 | 0.7321 | 0.9304 | 0.0082 | 0.0229 | 0.0202 | 0.0229 | 0.0306 | 0.0430 | 0.0866 | 0.1891 | 0.1262 | 0.1834 | 0.1688 | 0.2092 | 0.1494 | 0.1117 | 0.1501 | 0.1060 | 0.2599 | 0.1117 | 0.0017 | 0.0053 | 0.0122 | 0.0344 | 0.0780 | 0.1005 | 0.1089 | 0.1414 | 0.5176 | 25 | 37 | 53 | 75 | 105 | 143 | 192 | 255 | 344 | 0.0048 | 46.59 | 6.610 | 0.3171 | 41782.2 | 15900000 | 7490000000 | 4110000000000 | 0.4349 | 0.1994 | 0.0438 | 0.0012 | 0.1710 | 0.0129 | 0.2590 | 0.0915 | 0.1689 | 0.1419 | 0.1480 | 0.1792 | 0.0966 | 0.1929 | 0.0651 | 0.1402 | 0.0336 | 0.1134 | 0.0140 | 0.1269 | 0.0006 | 0.0000 | 0.0016 | 0.0011 | 0.0035 | 0.0031 | 0.0209 | 0.0133 | 0.0660 | 0.0570 | 0.1224 | 0.0997 | 0.0905 | 0.0754 | 0.1165 | 0.0996 | 0.5779 | 0.6509 | 0.0004 | 0.0013 | 0.0043 | 0.0044 | 0.0077 | 0.0109 | 0.0342 | 0.0455 | 0.0992 | 0.1166 | 0.1564 | 0.1705 | 0.1123 | 0.1236 | 0.1422 | 0.1484 | 0.4433 | 0.3789 | 0.0009 | 0.0019 | 0.0058 | 0.0251 | 0.0859 | 0.1396 | 0.1007 | 0.1336 | 0.5064 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 713 | 522 | | 16894 | 27359 | 277.6 | 52.05 | 216.35 | 215.57 | 208 | 237 | 256 | 269 | 281 | 294 | 306 | 320 | 341 | 0.0538 | 1471 | 1.091 | 103.16 | 31.06 | 2 | 0.0146 | 247 | 0.0019 | 13.94 | 6.613 | 0.2949 | 79797.3 | 23600000 | 7150000000 | 2220000000000 | 0.4393 | 0.2062 | 0.0005 | 0.0001 | 0.0011 | 0.0000 | 0.0033 | 0.0002 | 0.0092 | 0.0012 | 0.0381 | 0.0103 | 0.0669 | 0.0200 | 0.0670 | 0.0172 | 0.0957 | 0.0278 | 0.7182 | 0.9233 | 0.0001 | 0.0001 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0036 | 0.0009 | 0.0175 | 0.0093 | 0.0294 | 0.0173 | 0.0273 | 0.0120 | 0.0360 | 0.0204 | 0.8849 | 0.9400 | 0.0059 | 0.0000 | 0.0174 | 0.0000 | 0.0329 | 0.0000 | 0.0567 | 0.0000 | 0.1025 | 0.0000 | 0.1459 | 0.0000 | 0.1189 | 0.0000 | 0.1432 | 0.0000 | 0.3765 | 0.0000 | 0.0017 | 0.0028 | 0.0050 | 0.0176 | 0.0419 | 0.0771 | 0.0726 | 0.0997 | 0.6818 | 21 | 32 | 52 | 93 | 142 | 205 | 283 | 380 | 530 | 0.0112 | 32.03 | 6.315 | 0.3897 | 93278.7 | 53900000 | 36900000000 | 28400000000000 | 0.5194 | 0.1468 | 0.0368 | 0.0022 | 0.1715 | 0.0112 | 0.2748 | 0.0782 | 0.1614 | 0.1448 | 0.1334 | 0.1933 | 0.0945 | 0.1853 | 0.0577 | 0.1275 | 0.0408 | 0.1189 | 0.0291 | 0.1384 | 0.0004 | 0.0005 | 0.0011 | 0.0010 | 0.0036 | 0.0028 | 0.0148 | 0.0107 | 0.0581 | 0.0512 | 0.1064 | 0.0873 | 0.0753 | 0.0672 | 0.1096 | 0.0986 | 0.6307 | 0.6805 | 0.0004 | 0.0009 | 0.0014 | 0.0032 | 0.0066 | 0.0087 | 0.0278 | 0.0330 | 0.0781 | 0.0932 | 0.1289 | 0.1454 | 0.1017 | 0.1011 | 0.1260 | 0.1267 | 0.5291 | 0.4877 | 0.0007 | 0.0016 | 0.0048 | 0.0183 | 0.0725 | 0.1147 | 0.0880 | 0.1182 | 0.5812 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 351 | 817 | | 9511 | 24722 | 663.7 | 127.78 | 143.84 | 120.28 | 511 | 554 | 590 | 622 | 652 | 682 | 719 | 762 | 832 | 0.0415 | 1026 | 1.074 | 119.25 | 34.18 | 1 | 0.0296 | 282 | 0.0006 | 68.98 | 7.664 | 0.1441 | 456877.0 | 326000000 | 242000000000 | 186000000000000 | 0.4519 | 0.1968 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0094 | 0.0009 | 0.0457 | 0.0134 | 0.1036 | 0.0254 | 0.1111 | 0.0244 | 0.1527 | 0.0381 | 0.5755 | 0.8977 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0045 | 0.0000 | 0.0248 | 0.0094 | 0.0491 | 0.0164 | 0.0529 | 0.0124 | 0.0765 | 0.0208 | 0.7912 | 0.9411 | 0.0059 | 0.0087 | 0.0117 | 0.0145 | 0.0257 | 0.0378 | 0.0638 | 0.0698 | 0.1136 | 0.1337 | 0.1730 | 0.1890 | 0.0916 | 0.1105 | 0.1239 | 0.1570 | 0.3908 | 0.2791 | 0.0014 | 0.0027 | 0.0105 | 0.0302 | 0.0743 | 0.1243 | 0.1152 | 0.1353 | 0.5061 | 25 | 41 | 62 | 89 | 117 | 146 | 179 | 221 | 297 | 0.0086 | 17.29 | 5.757 | 0.3844 | 35156.3 | 12300000 | 5720000000 | 3420000000000 | 0.5257 | 0.1266 | 0.0343 | 0.0013 | 0.1241 | 0.0069 | 0.2250 | 0.0632 | 0.1641 | 0.1106 | 0.1554 | 0.1604 | 0.1191 | 0.1950 | 0.0806 | 0.1372 | 0.0561 | 0.1368 | 0.0413 | 0.1885 | 0.0002 | 0.0001 | 0.0011 | 0.0008 | 0.0035 | 0.0022 | 0.0199 | 0.0132 | 0.0765 | 0.0573 | 0.1252 | 0.1004 | 0.0980 | 0.0781 | 0.1344 | 0.1169 | 0.5411 | 0.6309 | 0.0025 | 0.0037 | 0.0041 | 0.0075 | 0.0118 | 0.0181 | 0.0405 | 0.0553 | 0.1145 | 0.1217 | 0.1629 | 0.1803 | 0.1285 | 0.1332 | 0.1493 | 0.1508 | 0.3858 | 0.3294 | 0.0009 | 0.0029 | 0.0080 | 0.0298 | 0.0939 | 0.1493 | 0.1124 | 0.1501 | 0.4528 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1104 | 606 | | 7792 | 17317 | 455.1 | 84.64 | 91.04 | 159.85 | 350 | 380 | 405 | 428 | 449 | 472 | 497 | 528 | 568 | 0.0587 | 1017 | 0.843 | 136.49 | 39.96 | 1 | 0.0508 | 396 | 0.0009 | 41.02 | 7.256 | 0.1774 | 214248.0 | 104000000 | 52400000000 | 27200000000000 | 0.4390 | 0.2040 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0038 | 0.0000 | 0.0136 | 0.0005 | 0.0498 | 0.0107 | 0.1097 | 0.0237 | 0.1108 | 0.0193 | 0.1486 | 0.0344 | 0.5627 | 0.9113 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0024 | 0.0000 | 0.0058 | 0.0004 | 0.0229 | 0.0095 | 0.0478 | 0.0189 | 0.0484 | 0.0112 | 0.0635 | 0.0227 | 0.8089 | 0.9373 | 0.0050 | 0.0153 | 0.0059 | 0.0153 | 0.0243 | 0.0458 | 0.0703 | 0.1756 | 0.1456 | 0.1221 | 0.1816 | 0.1603 | 0.1364 | 0.0916 | 0.1356 | 0.1069 | 0.2954 | 0.2672 | 0.0019 | 0.0038 | 0.0059 | 0.0261 | 0.0676 | 0.1051 | 0.0997 | 0.1070 | 0.5829 | 5 | 6 | 7 | 9 | 11 | 25 | 76 | 148 | 295 | 0.1599 | 22.17 | 4.036 | 0.5973 | 33837.1 | 18800000 | 12800000000 | 9900000000000 | 0.6360 | 0.0673 | 0.0357 | 0.0021 | 0.1417 | 0.0167 | 0.2200 | 0.0889 | 0.1536 | 0.1271 | 0.1497 | 0.1836 | 0.1249 | 0.1857 | 0.0694 | 0.1130 | 0.0565 | 0.1130 | 0.0486 | 0.1700 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0006 | 0.0003 | 0.0113 | 0.0062 | 0.0430 | 0.0382 | 0.0708 | 0.0689 | 0.0549 | 0.0430 | 0.0815 | 0.0753 | 0.7371 | 0.7679 | 0.0002 | 0.0000 | 0.0005 | 0.0010 | 0.0049 | 0.0052 | 0.0117 | 0.0160 | 0.0608 | 0.0640 | 0.0963 | 0.1006 | 0.0629 | 0.0694 | 0.0974 | 0.1091 | 0.6653 | 0.6349 | 0.0002 | 0.0006 | 0.0023 | 0.0121 | 0.0489 | 0.0886 | 0.0606 | 0.0917 | 0.6949 |