High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1199 | 269 | | 6858 | 34380 | 182.5 | 52.85 | 124.86 | 199.10 | 122 | 141 | 154 | 165 | 177 | 190 | 204 | 222 | 256 | 0.0332 | 1142 | 0.787 | 31.00 | 8.06 | 3 | 0.0117 | 80 | 0.0011 | 37.84 | 7.176 | 0.1947 | 36107.4 | 7670000 | 1740000000 | 418000000000 | 0.4164 | 0.2188 | 0.0008 | 0.0000 | 0.0016 | 0.0003 | 0.0074 | 0.0003 | 0.0251 | 0.0031 | 0.0740 | 0.0238 | 0.1294 | 0.0417 | 0.1524 | 0.0466 | 0.1762 | 0.0732 | 0.4332 | 0.8108 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0034 | 0.0000 | 0.0103 | 0.0012 | 0.0321 | 0.0128 | 0.0530 | 0.0208 | 0.0614 | 0.0187 | 0.0821 | 0.0317 | 0.7569 | 0.9147 | 0.0035 | 0.0089 | 0.0090 | 0.0089 | 0.0097 | 0.0222 | 0.0520 | 0.0532 | 0.0929 | 0.1064 | 0.1283 | 0.1241 | 0.0999 | 0.1004 | 0.1200 | 0.1241 | 0.4847 | 0.4520 | 0.0016 | 0.0038 | 0.0074 | 0.0272 | 0.0579 | 0.0886 | 0.0908 | 0.1164 | 0.6063 | 17 | 21 | 25 | 29 | 35 | 48 | 91 | 194 | 364 | 0.0577 | 29.38 | 4.737 | 0.5383 | 55230.0 | 41200000 | 40500000000 | 47700000000000 | 0.3925 | 0.2378 | 0.1380 | 0.0050 | 0.3601 | 0.0465 | 0.2981 | 0.2724 | 0.1080 | 0.2297 | 0.0587 | 0.1914 | 0.0244 | 0.1219 | 0.0089 | 0.0649 | 0.0028 | 0.0419 | 0.0011 | 0.0263 | 0.0001 | 0.0001 | 0.0004 | 0.0005 | 0.0019 | 0.0020 | 0.0186 | 0.0147 | 0.0758 | 0.0670 | 0.1162 | 0.0990 | 0.0798 | 0.0694 | 0.1195 | 0.1071 | 0.5878 | 0.6402 | 0.0002 | 0.0003 | 0.0007 | 0.0022 | 0.0033 | 0.0056 | 0.0256 | 0.0302 | 0.0905 | 0.0964 | 0.1439 | 0.1483 | 0.0934 | 0.1014 | 0.1314 | 0.1378 | 0.5108 | 0.4778 | 0.0002 | 0.0007 | 0.0022 | 0.0238 | 0.0786 | 0.1331 | 0.0854 | 0.1281 | 0.5480 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 524 | 311 | | 7833 | 16316 | 159.4 | 129.05 | 84.65 | 174.06 | 65 | 76 | 86 | 97 | 114 | 131 | 150 | 185 | 382 | 0.0834 | 1360 | 1.188 | 60.96 | 23.71 | 5 | 0.0200 | 157 | 0.0057 | 7.18 | 5.903 | 0.4831 | 42052.4 | 16100000 | 7440000000 | 3750000000000 | 0.4134 | 0.2024 | 0.0022 | 0.0044 | 0.0039 | 0.0032 | 0.0061 | 0.0041 | 0.0335 | 0.0116 | 0.0754 | 0.0367 | 0.0972 | 0.0576 | 0.0972 | 0.0547 | 0.1056 | 0.0789 | 0.5788 | 0.7488 | 0.0012 | 0.0031 | 0.0021 | 0.0023 | 0.0027 | 0.0029 | 0.0140 | 0.0079 | 0.0273 | 0.0211 | 0.0334 | 0.0280 | 0.0404 | 0.0320 | 0.0507 | 0.0445 | 0.8282 | 0.8580 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0033 | 0.0000 | 0.0086 | 0.0022 | 0.0213 | 0.0230 | 0.0452 | 0.0445 | 0.0219 | 0.0208 | 0.0359 | 0.0408 | 0.8625 | 0.8687 | 0.0005 | 0.0039 | 0.0043 | 0.0096 | 0.0294 | 0.0487 | 0.0352 | 0.0545 | 0.8140 | 8 | 10 | 12 | 15 | 18 | 24 | 39 | 87 | 242 | 0.1992 | 8.64 | 2.988 | 0.7068 | 37461.6 | 26400000 | 22100000000 | 20600000000000 | 0.5330 | 0.1352 | 0.0090 | 0.0029 | 0.0336 | 0.0070 | 0.0493 | 0.0187 | 0.1087 | 0.0531 | 0.1659 | 0.0904 | 0.1839 | 0.1376 | 0.1390 | 0.1405 | 0.1312 | 0.1359 | 0.1794 | 0.4140 | 0.0005 | 0.0009 | 0.0029 | 0.0023 | 0.0029 | 0.0042 | 0.0098 | 0.0168 | 0.0383 | 0.0349 | 0.0554 | 0.0519 | 0.0449 | 0.0496 | 0.0660 | 0.0575 | 0.7794 | 0.7817 | 0.0021 | 0.0004 | 0.0017 | 0.0035 | 0.0045 | 0.0047 | 0.0141 | 0.0116 | 0.0497 | 0.0520 | 0.0783 | 0.0849 | 0.0583 | 0.0621 | 0.0852 | 0.0791 | 0.7060 | 0.7017 | 0.0009 | 0.0033 | 0.0045 | 0.0117 | 0.0415 | 0.0667 | 0.0505 | 0.0739 | 0.7471 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 267 | 437 | | 13592 | 31269 | 301.0 | 63.57 | 169.76 | 203.21 | 225 | 246 | 263 | 279 | 295 | 313 | 331 | 353 | 386 | 0.0450 | 1407 | 0.991 | 116.62 | 32.28 | 1 | 0.0211 | 287 | 0.0005 | 80.82 | 7.811 | 0.1322 | 94652.1 | 31000000 | 10600000000 | 3760000000000 | 0.4501 | 0.1998 | 0.0000 | 0.0000 | 0.0006 | 0.0002 | 0.0033 | 0.0002 | 0.0168 | 0.0009 | 0.0656 | 0.0133 | 0.1325 | 0.0320 | 0.1576 | 0.0360 | 0.1861 | 0.0572 | 0.4376 | 0.8603 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0001 | 0.0063 | 0.0004 | 0.0276 | 0.0084 | 0.0557 | 0.0188 | 0.0701 | 0.0154 | 0.0900 | 0.0249 | 0.7485 | 0.9321 | 0.0051 | 0.0171 | 0.0085 | 0.0240 | 0.0315 | 0.0719 | 0.0817 | 0.1199 | 0.1430 | 0.1747 | 0.1750 | 0.1695 | 0.1222 | 0.0925 | 0.1384 | 0.1318 | 0.2946 | 0.1986 | 0.0011 | 0.0024 | 0.0080 | 0.0318 | 0.0799 | 0.1235 | 0.1033 | 0.1392 | 0.5107 | 16 | 20 | 25 | 36 | 65 | 122 | 216 | 331 | 478 | 0.0295 | 54.42 | 5.957 | 0.4239 | 70109.3 | 38900000 | 25400000000 | 18600000000000 | 0.4659 | 0.1579 | 0.1220 | 0.0013 | 0.3239 | 0.0267 | 0.3147 | 0.2497 | 0.1092 | 0.2318 | 0.0683 | 0.1799 | 0.0358 | 0.1321 | 0.0147 | 0.0764 | 0.0073 | 0.0559 | 0.0041 | 0.0461 | 0.0003 | 0.0001 | 0.0008 | 0.0004 | 0.0024 | 0.0013 | 0.0139 | 0.0099 | 0.0651 | 0.0580 | 0.1046 | 0.0910 | 0.0733 | 0.0686 | 0.1102 | 0.1024 | 0.6295 | 0.6682 | 0.0002 | 0.0003 | 0.0011 | 0.0020 | 0.0039 | 0.0045 | 0.0192 | 0.0256 | 0.0810 | 0.0887 | 0.1246 | 0.1262 | 0.0858 | 0.0977 | 0.1320 | 0.1374 | 0.5522 | 0.5175 | 0.0001 | 0.0012 | 0.0027 | 0.0147 | 0.0721 | 0.1162 | 0.0811 | 0.1158 | 0.5962 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1167 | 689 | | 6111 | 11010 | 86.5 | 25.63 | 194.11 | 227.36 | 55 | 64 | 71 | 78 | 84 | 91 | 98 | 107 | 121 | 0.0750 | 826 | 0.733 | 215.47 | 54.20 | 4 | 0.0928 | 567 | 0.0034 | 11.76 | 5.994 | 0.3193 | 8137.3 | 828575 | 90900000 | 10700000000 | 0.4313 | 0.2183 | 0.0010 | 0.0004 | 0.0045 | 0.0006 | 0.0156 | 0.0018 | 0.0448 | 0.0075 | 0.1171 | 0.0342 | 0.1801 | 0.0744 | 0.1674 | 0.0795 | 0.1944 | 0.1213 | 0.2751 | 0.6804 | 0.0004 | 0.0004 | 0.0011 | 0.0000 | 0.0033 | 0.0004 | 0.0100 | 0.0028 | 0.0462 | 0.0179 | 0.0736 | 0.0369 | 0.0694 | 0.0341 | 0.1040 | 0.0529 | 0.6918 | 0.8547 | 0.0057 | 0.0065 | 0.0086 | 0.0161 | 0.0179 | 0.0581 | 0.0622 | 0.1113 | 0.1237 | 0.1597 | 0.1587 | 0.1968 | 0.1244 | 0.1323 | 0.1494 | 0.1419 | 0.3495 | 0.1774 | 0.0020 | 0.0037 | 0.0116 | 0.0317 | 0.0810 | 0.1161 | 0.1045 | 0.1324 | 0.5170 | 14 | 18 | 27 | 51 | 94 | 159 | 248 | 359 | 533 | 0.0198 | 121.90 | 6.448 | 0.3047 | 89366.6 | 55800000 | 41100000000 | 34000000000000 | 0.4757 | 0.1749 | 0.0822 | 0.0030 | 0.2716 | 0.0287 | 0.3153 | 0.2000 | 0.1093 | 0.1713 | 0.1103 | 0.1866 | 0.0562 | 0.1683 | 0.0416 | 0.0896 | 0.0083 | 0.0733 | 0.0052 | 0.0792 | 0.0007 | 0.0002 | 0.0002 | 0.0008 | 0.0034 | 0.0016 | 0.0104 | 0.0093 | 0.0707 | 0.0599 | 0.1227 | 0.1136 | 0.0860 | 0.0717 | 0.1146 | 0.1087 | 0.5914 | 0.6343 | 0.0006 | 0.0007 | 0.0014 | 0.0039 | 0.0046 | 0.0079 | 0.0149 | 0.0201 | 0.0879 | 0.0911 | 0.1479 | 0.1601 | 0.0948 | 0.0999 | 0.1390 | 0.1443 | 0.5088 | 0.4721 | 0.0003 | 0.0018 | 0.0059 | 0.0132 | 0.0749 | 0.1391 | 0.0892 | 0.1302 | 0.5455 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 686 | 761 | | 4278 | 10329 | 575.0 | 101.74 | 209.00 | 348.06 | 451 | 485 | 515 | 540 | 564 | 591 | 619 | 660 | 717 | 0.0947 | 978 | 1.233 | 88.57 | 39.70 | 1 | 0.0570 | 244 | 0.0015 | 26.90 | 6.732 | 0.2213 | 340946.0 | 208000000 | 131000000000 | 85100000000000 | 0.4370 | 0.2089 | 0.0003 | 0.0002 | 0.0016 | 0.0000 | 0.0010 | 0.0000 | 0.0070 | 0.0005 | 0.0491 | 0.0165 | 0.1035 | 0.0326 | 0.1032 | 0.0271 | 0.1478 | 0.0398 | 0.5865 | 0.8833 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0005 | 0.0000 | 0.0035 | 0.0002 | 0.0289 | 0.0138 | 0.0516 | 0.0248 | 0.0503 | 0.0145 | 0.0751 | 0.0227 | 0.7893 | 0.9239 | 0.0017 | 0.0000 | 0.0017 | 0.0408 | 0.0166 | 0.0510 | 0.0582 | 0.1633 | 0.1481 | 0.2041 | 0.1681 | 0.2245 | 0.0899 | 0.0714 | 0.1514 | 0.1633 | 0.3644 | 0.0816 | 0.0010 | 0.0000 | 0.0051 | 0.0314 | 0.0663 | 0.1352 | 0.1023 | 0.1180 | 0.5408 | 9 | 10 | 12 | 14 | 19 | 49 | 188 | 394 | 707 | 0.1793 | 74.24 | 4.505 | 0.5801 | 164813.0 | 178000000 | 227000000000 | 323000000000000 | 0.5252 | 0.1228 | 0.1229 | 0.0022 | 0.3301 | 0.0673 | 0.2337 | 0.2076 | 0.1108 | 0.1987 | 0.0723 | 0.2065 | 0.0723 | 0.1358 | 0.0313 | 0.0550 | 0.0193 | 0.0673 | 0.0072 | 0.0595 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0013 | 0.0020 | 0.0041 | 0.0055 | 0.0525 | 0.0486 | 0.0965 | 0.0858 | 0.0600 | 0.0532 | 0.0839 | 0.0776 | 0.7008 | 0.7272 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0014 | 0.0012 | 0.0090 | 0.0196 | 0.0690 | 0.0667 | 0.1063 | 0.1181 | 0.0788 | 0.0895 | 0.1095 | 0.1071 | 0.6259 | 0.5958 | 0.0000 | 0.0003 | 0.0000 | 0.0104 | 0.0509 | 0.1031 | 0.0686 | 0.0961 | 0.6707 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 919 | 347 | | 5602 | 6122 | 469.4 | 79.21 | 27.49 | 47.62 | 357 | 396 | 427 | 455 | 479 | 496 | 513 | 531 | 559 | 0.1042 | 638 | 0.998 | 133.18 | 37.86 | 1 | 0.0605 | 339 | 0.0017 | 16.11 | 6.642 | 0.3084 | 226643.0 | 112000000 | 57000000000 | 29500000000000 | 0.4201 | 0.2305 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0033 | 0.0000 | 0.0068 | 0.0007 | 0.0224 | 0.0104 | 0.0352 | 0.0294 | 0.0373 | 0.0137 | 0.0623 | 0.0225 | 0.8308 | 0.9233 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0025 | 0.0000 | 0.0042 | 0.0005 | 0.0136 | 0.0097 | 0.0247 | 0.0272 | 0.0207 | 0.0098 | 0.0262 | 0.0177 | 0.9067 | 0.9351 | 0.0187 | 0.0000 | 0.0093 | 0.0541 | 0.0093 | 0.0811 | 0.0318 | 0.1622 | 0.0486 | 0.1892 | 0.0542 | 0.1892 | 0.0710 | 0.0811 | 0.0841 | 0.1351 | 0.6729 | 0.1081 | 0.0000 | 0.0020 | 0.0049 | 0.0120 | 0.0273 | 0.0462 | 0.0524 | 0.0908 | 0.7645 | 8 | 10 | 12 | 14 | 15 | 17 | 20 | 29 | 50 | 0.3237 | 1.45 | 2.056 | 0.8309 | 3023.4 | 1020000 | 532000000 | 337000000000 | 0.5358 | 0.1270 | 0.0965 | 0.0392 | 0.0856 | 0.0530 | 0.0911 | 0.0723 | 0.1111 | 0.0933 | 0.1840 | 0.1154 | 0.1858 | 0.1198 | 0.1056 | 0.1375 | 0.1093 | 0.1452 | 0.0310 | 0.2242 | 0.0300 | 0.0239 | 0.0257 | 0.0316 | 0.0178 | 0.0421 | 0.0165 | 0.0541 | 0.0484 | 0.0733 | 0.0772 | 0.0824 | 0.0502 | 0.0798 | 0.0876 | 0.0900 | 0.6467 | 0.5229 | 0.0018 | 0.0011 | 0.0092 | 0.0063 | 0.0111 | 0.0138 | 0.0129 | 0.0180 | 0.0563 | 0.0624 | 0.0969 | 0.0963 | 0.0572 | 0.0709 | 0.0895 | 0.1270 | 0.6651 | 0.6042 | 0.0092 | 0.0077 | 0.0061 | 0.0146 | 0.0452 | 0.0958 | 0.0598 | 0.0782 | 0.6835 | ||
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 179 | 861 | | 6894 | 24993 | 432.7 | 77.04 | 123.09 | 229.52 | 337 | 363 | 385 | 406 | 427 | 448 | 470 | 497 | 536 | 0.0541 | 1352 | 1.247 | 106.10 | 42.20 | 2 | 0.0392 | 270 | 0.0024 | 14.62 | 6.292 | 0.2830 | 193164.0 | 88900000 | 42200000000 | 20600000000000 | 0.4573 | 0.1908 | 0.0002 | 0.0000 | 0.0008 | 0.0000 | 0.0034 | 0.0000 | 0.0121 | 0.0006 | 0.0472 | 0.0149 | 0.0960 | 0.0253 | 0.1212 | 0.0267 | 0.1545 | 0.0354 | 0.5647 | 0.8972 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0017 | 0.0000 | 0.0065 | 0.0001 | 0.0253 | 0.0121 | 0.0467 | 0.0177 | 0.0549 | 0.0126 | 0.0783 | 0.0167 | 0.7863 | 0.9408 | 0.0053 | 0.0000 | 0.0160 | 0.0701 | 0.0299 | 0.0764 | 0.0812 | 0.1783 | 0.1335 | 0.1720 | 0.1656 | 0.1783 | 0.1186 | 0.1274 | 0.1346 | 0.0955 | 0.3152 | 0.1019 | 0.0009 | 0.0037 | 0.0079 | 0.0244 | 0.0711 | 0.1200 | 0.1053 | 0.1236 | 0.5430 | 8 | 10 | 12 | 13 | 16 | 23 | 63 | 188 | 422 | 0.2078 | 29.75 | 3.972 | 0.6370 | 67827.8 | 55500000 | 55600000000 | 63900000000000 | 0.4521 | 0.1694 | 0.1333 | 0.0042 | 0.3651 | 0.0371 | 0.3035 | 0.2123 | 0.1120 | 0.2751 | 0.0504 | 0.2537 | 0.0202 | 0.1124 | 0.0090 | 0.0570 | 0.0045 | 0.0314 | 0.0022 | 0.0167 | 0.0002 | 0.0000 | 0.0002 | 0.0003 | 0.0014 | 0.0008 | 0.0135 | 0.0108 | 0.0527 | 0.0490 | 0.0825 | 0.0789 | 0.0578 | 0.0500 | 0.0808 | 0.0738 | 0.7110 | 0.7365 | 0.0002 | 0.0004 | 0.0009 | 0.0010 | 0.0018 | 0.0029 | 0.0147 | 0.0130 | 0.0575 | 0.0617 | 0.0963 | 0.1072 | 0.0686 | 0.0675 | 0.0945 | 0.1032 | 0.6655 | 0.6432 | 0.0007 | 0.0005 | 0.0013 | 0.0119 | 0.0549 | 0.0931 | 0.0549 | 0.0860 | 0.6968 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1301 | 922 | | 1366 | 2845 | 88.3 | 15.42 | 119.74 | 63.45 | 71 | 75 | 79 | 82 | 86 | 89 | 94 | 101 | 110 | 0.1547 | 440 | 0.932 | 89.36 | 30.02 | 1 | 0.1808 | 247 | 0.0068 | 9.05 | 5.271 | 0.3306 | 8028.3 | 753530 | 73100000 | 7320000000 | 0.4490 | 0.1982 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0058 | 0.0000 | 0.0164 | 0.0023 | 0.0733 | 0.0233 | 0.1485 | 0.0593 | 0.1736 | 0.0360 | 0.2343 | 0.0765 | 0.3481 | 0.8027 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0081 | 0.0022 | 0.0422 | 0.0205 | 0.0755 | 0.0490 | 0.0739 | 0.0190 | 0.1226 | 0.0381 | 0.6761 | 0.8712 | 0.0256 | 0.0303 | 0.0615 | 0.1515 | 0.0308 | 0.1515 | 0.1538 | 0.1212 | 0.1538 | 0.1515 | 0.1590 | 0.2121 | 0.1385 | 0.0909 | 0.1590 | 0.0606 | 0.1179 | 0.0303 | 0.0065 | 0.0114 | 0.0244 | 0.0603 | 0.0945 | 0.1222 | 0.1596 | 0.1417 | 0.3795 | 46 | 63 | 81 | 98 | 113 | 127 | 144 | 167 | 202 | 0.0075 | 7.31 | 5.265 | 0.4258 | 18362.3 | 3410000 | 742000000 | 186000000000 | 0.5900 | 0.1093 | 0.0045 | 0.0032 | 0.0465 | 0.0127 | 0.1213 | 0.0222 | 0.1122 | 0.0565 | 0.1655 | 0.1016 | 0.1565 | 0.1479 | 0.1565 | 0.1384 | 0.1168 | 0.1625 | 0.1202 | 0.3549 | 0.0000 | 0.0019 | 0.0063 | 0.0042 | 0.0091 | 0.0070 | 0.0223 | 0.0164 | 0.0566 | 0.0529 | 0.1189 | 0.0791 | 0.0840 | 0.0669 | 0.1309 | 0.0993 | 0.5720 | 0.6723 | 0.0046 | 0.0107 | 0.0092 | 0.0143 | 0.0288 | 0.0481 | 0.0714 | 0.1016 | 0.1429 | 0.1373 | 0.1705 | 0.1836 | 0.1244 | 0.1390 | 0.1244 | 0.1622 | 0.3237 | 0.2032 | 0.0000 | 0.0101 | 0.0155 | 0.0364 | 0.1006 | 0.1509 | 0.1223 | 0.1409 | 0.4234 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 438 | 338 | | 5309 | 17377 | 254.0 | 51.30 | 154.44 | 205.30 | 192 | 208 | 222 | 236 | 250 | 263 | 278 | 296 | 323 | 0.0642 | 1116 | 0.650 | 145.45 | 37.54 | 1 | 0.0868 | 461 | 0.0009 | 54.07 | 7.276 | 0.1615 | 67165.6 | 18500000 | 5270000000 | 1560000000000 | 0.4223 | 0.2163 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0065 | 0.0004 | 0.0185 | 0.0008 | 0.0648 | 0.0167 | 0.1339 | 0.0415 | 0.1444 | 0.0348 | 0.1632 | 0.0518 | 0.4682 | 0.8540 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0025 | 0.0000 | 0.0094 | 0.0004 | 0.0315 | 0.0125 | 0.0602 | 0.0262 | 0.0616 | 0.0142 | 0.0778 | 0.0232 | 0.7567 | 0.9236 | 0.0092 | 0.0185 | 0.0150 | 0.0139 | 0.0242 | 0.0509 | 0.0715 | 0.1667 | 0.1349 | 0.1944 | 0.1915 | 0.1944 | 0.1165 | 0.0972 | 0.1442 | 0.1065 | 0.2930 | 0.1574 | 0.0016 | 0.0032 | 0.0068 | 0.0275 | 0.0749 | 0.1247 | 0.1064 | 0.1466 | 0.5084 | 13 | 15 | 18 | 23 | 36 | 81 | 184 | 315 | 474 | 0.0496 | 33.73 | 5.257 | 0.4918 | 65995.6 | 37600000 | 25100000000 | 18900000000000 | 0.5553 | 0.1158 | 0.0613 | 0.0005 | 0.2441 | 0.0274 | 0.3613 | 0.1747 | 0.1129 | 0.1642 | 0.0914 | 0.2211 | 0.0581 | 0.1832 | 0.0280 | 0.0932 | 0.0258 | 0.0658 | 0.0172 | 0.0700 | 0.0000 | 0.0000 | 0.0005 | 0.0001 | 0.0008 | 0.0007 | 0.0082 | 0.0069 | 0.0483 | 0.0458 | 0.0858 | 0.0729 | 0.0508 | 0.0451 | 0.0837 | 0.0765 | 0.7219 | 0.7519 | 0.0002 | 0.0000 | 0.0004 | 0.0004 | 0.0008 | 0.0017 | 0.0152 | 0.0196 | 0.0552 | 0.0582 | 0.1050 | 0.1163 | 0.0616 | 0.0694 | 0.0952 | 0.0936 | 0.6664 | 0.6407 | 0.0000 | 0.0007 | 0.0011 | 0.0112 | 0.0520 | 0.0947 | 0.0605 | 0.0867 | 0.6931 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 854 | 856 | | 7221 | 14570 | 49.4 | 17.53 | 78.00 | 136.28 | 28 | 34 | 38 | 43 | 47 | 52 | 58 | 64 | 73 | 0.0925 | 1347 | 0.564 | 226.82 | 39.32 | 13 | 0.0867 | 626 | 0.0060 | 6.82 | 5.419 | 0.3768 | 2746.4 | 169000 | 11300000 | 819000000 | 0.4385 | 0.1979 | 0.0021 | 0.0002 | 0.0092 | 0.0013 | 0.0509 | 0.0036 | 0.1206 | 0.0209 | 0.1835 | 0.0519 | 0.1998 | 0.1171 | 0.1729 | 0.1192 | 0.1266 | 0.1517 | 0.1344 | 0.5342 | 0.0004 | 0.0000 | 0.0012 | 0.0005 | 0.0037 | 0.0013 | 0.0217 | 0.0112 | 0.0562 | 0.0266 | 0.0864 | 0.0540 | 0.0848 | 0.0579 | 0.1085 | 0.0691 | 0.6371 | 0.7796 | 0.0039 | 0.0097 | 0.0073 | 0.0154 | 0.0194 | 0.0328 | 0.0682 | 0.0936 | 0.1094 | 0.1380 | 0.1510 | 0.1979 | 0.1292 | 0.1342 | 0.1549 | 0.1467 | 0.3567 | 0.2317 | 0.0017 | 0.0026 | 0.0125 | 0.0408 | 0.0755 | 0.1098 | 0.1078 | 0.1329 | 0.5163 | 11 | 13 | 15 | 17 | 20 | 26 | 46 | 104 | 234 | 0.1860 | 10.58 | 3.510 | 0.6862 | 24655.2 | 13200000 | 8940000000 | 7000000000000 | 0.6410 | 0.1101 | 0.1548 | 0.0039 | 0.3289 | 0.0394 | 0.2946 | 0.2229 | 0.1131 | 0.2327 | 0.0565 | 0.2189 | 0.0298 | 0.1433 | 0.0134 | 0.0671 | 0.0074 | 0.0493 | 0.0015 | 0.0224 | 0.0008 | 0.0002 | 0.0008 | 0.0005 | 0.0032 | 0.0053 | 0.0201 | 0.0138 | 0.0823 | 0.0766 | 0.1173 | 0.0994 | 0.0839 | 0.0713 | 0.1284 | 0.1266 | 0.5631 | 0.6063 | 0.0003 | 0.0007 | 0.0023 | 0.0021 | 0.0058 | 0.0053 | 0.0229 | 0.0248 | 0.1011 | 0.1076 | 0.1308 | 0.1522 | 0.0995 | 0.0995 | 0.1485 | 0.1501 | 0.4889 | 0.4577 | 0.0000 | 0.0023 | 0.0053 | 0.0197 | 0.0978 | 0.1169 | 0.0934 | 0.1436 | 0.5211 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 999 | 759 | | 7014 | 22115 | 261.5 | 51.41 | 152.85 | 246.06 | 199 | 217 | 231 | 244 | 257 | 271 | 286 | 305 | 332 | 0.0572 | 1264 | 0.703 | 157.81 | 44.60 | 2 | 0.0720 | 505 | 0.0008 | 54.08 | 7.368 | 0.1589 | 71002.4 | 20000000 | 5820000000 | 1750000000000 | 0.4542 | 0.2013 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0043 | 0.0000 | 0.0198 | 0.0018 | 0.0614 | 0.0168 | 0.1165 | 0.0363 | 0.1431 | 0.0312 | 0.1561 | 0.0529 | 0.4986 | 0.8610 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0065 | 0.0007 | 0.0317 | 0.0127 | 0.0548 | 0.0245 | 0.0634 | 0.0171 | 0.0806 | 0.0298 | 0.7622 | 0.9151 | 0.0035 | 0.0142 | 0.0132 | 0.0474 | 0.0307 | 0.0664 | 0.0729 | 0.1232 | 0.1484 | 0.2133 | 0.1756 | 0.1706 | 0.1089 | 0.1611 | 0.1528 | 0.1137 | 0.2941 | 0.0900 | 0.0009 | 0.0021 | 0.0081 | 0.0332 | 0.0865 | 0.1293 | 0.1164 | 0.1320 | 0.4914 | 9 | 11 | 12 | 14 | 18 | 37 | 127 | 301 | 523 | 0.1005 | 52.42 | 4.809 | 0.5431 | 83904.9 | 63400000 | 57600000000 | 60200000000000 | 0.4909 | 0.1549 | 0.1011 | 0.0081 | 0.3100 | 0.0501 | 0.3478 | 0.2536 | 0.1133 | 0.2036 | 0.0800 | 0.1659 | 0.0233 | 0.1438 | 0.0122 | 0.0845 | 0.0067 | 0.0549 | 0.0056 | 0.0355 | 0.0001 | 0.0004 | 0.0009 | 0.0006 | 0.0022 | 0.0018 | 0.0097 | 0.0091 | 0.0460 | 0.0426 | 0.0824 | 0.0794 | 0.0515 | 0.0480 | 0.0790 | 0.0681 | 0.7281 | 0.7501 | 0.0000 | 0.0007 | 0.0015 | 0.0024 | 0.0028 | 0.0041 | 0.0143 | 0.0111 | 0.0528 | 0.0560 | 0.0945 | 0.1016 | 0.0625 | 0.0621 | 0.0883 | 0.0970 | 0.6834 | 0.6651 | 0.0003 | 0.0006 | 0.0019 | 0.0083 | 0.0525 | 0.0906 | 0.0541 | 0.0823 | 0.7093 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 125 | 813 | | 4044 | 8852 | 602.6 | 91.52 | 41.19 | 63.75 | 467 | 546 | 581 | 603 | 621 | 637 | 653 | 670 | 697 | 0.0916 | 811 | 0.861 | 103.18 | 25.63 | 4 | 0.0601 | 243 | 0.0019 | 32.85 | 6.649 | 0.2422 | 371488.0 | 233000000 | 149000000000 | 95900000000000 | 0.4344 | 0.2018 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0029 | 0.0008 | 0.0262 | 0.0168 | 0.0455 | 0.0300 | 0.0385 | 0.0173 | 0.0691 | 0.0297 | 0.8172 | 0.9055 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0008 | 0.0201 | 0.0167 | 0.0321 | 0.0289 | 0.0201 | 0.0157 | 0.0338 | 0.0282 | 0.8928 | 0.9097 | 0.0279 | 0.0000 | 0.0391 | 0.0000 | 0.0615 | 0.1429 | 0.1006 | 0.2857 | 0.1006 | 0.2857 | 0.1564 | 0.2857 | 0.1229 | 0.0000 | 0.0950 | 0.0000 | 0.2961 | 0.0000 | 0.0008 | 0.0021 | 0.0062 | 0.0181 | 0.0402 | 0.0743 | 0.0812 | 0.0952 | 0.6820 | 9 | 11 | 14 | 16 | 19 | 24 | 32 | 45 | 88 | 0.0559 | 3.74 | 3.856 | 0.6364 | 5760.6 | 1520000 | 505000000 | 191000000000 | 0.4879 | 0.1680 | 0.0222 | 0.0179 | 0.0677 | 0.0335 | 0.0812 | 0.0288 | 0.1141 | 0.0594 | 0.1460 | 0.0957 | 0.1470 | 0.0868 | 0.1692 | 0.1094 | 0.1335 | 0.1627 | 0.1190 | 0.4059 | 0.0058 | 0.0099 | 0.0173 | 0.0192 | 0.0142 | 0.0128 | 0.0242 | 0.0271 | 0.0468 | 0.0434 | 0.0560 | 0.0449 | 0.0629 | 0.0545 | 0.0844 | 0.0813 | 0.6884 | 0.7067 | 0.0032 | 0.0069 | 0.0153 | 0.0122 | 0.0159 | 0.0130 | 0.0312 | 0.0298 | 0.0503 | 0.0519 | 0.0751 | 0.0833 | 0.0649 | 0.0596 | 0.0808 | 0.0795 | 0.6635 | 0.6639 | 0.0049 | 0.0113 | 0.0157 | 0.0300 | 0.0458 | 0.0679 | 0.0684 | 0.0915 | 0.6644 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 182 | 324 | | 4862 | 8847 | 382.1 | 46.56 | 84.31 | 223.89 | 321 | 348 | 363 | 376 | 385 | 395 | 406 | 419 | 440 | 0.0849 | 751 | 0.869 | 141.40 | 42.45 | 2 | 0.0755 | 367 | 0.0020 | 27.89 | 6.580 | 0.2423 | 148135.0 | 58200000 | 23200000000 | 9310000000000 | 0.4327 | 0.2087 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0044 | 0.0000 | 0.0215 | 0.0134 | 0.0430 | 0.0245 | 0.0423 | 0.0117 | 0.0642 | 0.0210 | 0.8233 | 0.9294 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0018 | 0.0000 | 0.0153 | 0.0134 | 0.0306 | 0.0245 | 0.0237 | 0.0117 | 0.0317 | 0.0210 | 0.8966 | 0.9294 | 0.0214 | 0.0000 | 0.0856 | 0.0000 | 0.1016 | 0.0000 | 0.1283 | 0.0000 | 0.1176 | 0.0000 | 0.1444 | 0.0000 | 0.1016 | 0.0000 | 0.1123 | 0.0000 | 0.1872 | 0.0000 | 0.0019 | 0.0049 | 0.0106 | 0.0314 | 0.0538 | 0.0947 | 0.0981 | 0.1163 | 0.5883 | 8 | 9 | 11 | 12 | 13 | 15 | 20 | 43 | 199 | 0.1434 | 6.44 | 2.531 | 0.5616 | 57228.9 | 60400000 | 73600000000 | 96900000000000 | 0.7057 | 0.0462 | 0.0466 | 0.0000 | 0.0975 | 0.0157 | 0.2458 | 0.0747 | 0.1144 | 0.1041 | 0.1653 | 0.1434 | 0.1483 | 0.1945 | 0.1102 | 0.1611 | 0.0466 | 0.1336 | 0.0254 | 0.1729 | 0.0007 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0048 | 0.0144 | 0.0133 | 0.0390 | 0.0387 | 0.0787 | 0.0678 | 0.0568 | 0.0599 | 0.1026 | 0.0998 | 0.7066 | 0.7145 | 0.0000 | 0.0000 | 0.0000 | 0.0035 | 0.0016 | 0.0009 | 0.0122 | 0.0192 | 0.0636 | 0.0603 | 0.0865 | 0.0857 | 0.0530 | 0.0594 | 0.1117 | 0.0970 | 0.6713 | 0.6740 | 0.0000 | 0.0008 | 0.0023 | 0.0129 | 0.0530 | 0.0802 | 0.0560 | 0.1104 | 0.6846 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1028 | 231 | | 11368 | 9358 | 393.3 | 133.58 | 93.30 | 136.68 | 187 | 274 | 336 | 383 | 422 | 451 | 481 | 509 | 544 | 0.1038 | 971 | 0.530 | 101.02 | 17.03 | 7 | 0.0223 | 254 | 0.0009 | 24.62 | 7.358 | 0.2464 | 172513.0 | 80400000 | 39000000000 | 19500000000000 | 0.5210 | 0.1387 | 0.0011 | 0.0006 | 0.0017 | 0.0005 | 0.0047 | 0.0018 | 0.0170 | 0.0049 | 0.0766 | 0.0277 | 0.1275 | 0.0545 | 0.1031 | 0.0384 | 0.1389 | 0.0594 | 0.5294 | 0.8122 | 0.0000 | 0.0001 | 0.0001 | 0.0001 | 0.0000 | 0.0002 | 0.0023 | 0.0012 | 0.0230 | 0.0184 | 0.0392 | 0.0346 | 0.0241 | 0.0188 | 0.0387 | 0.0285 | 0.8726 | 0.8980 | 0.0005 | 0.0000 | 0.0029 | 0.0000 | 0.0061 | 0.0000 | 0.0163 | 0.0000 | 0.0472 | 0.0000 | 0.0674 | 0.0000 | 0.0653 | 0.0000 | 0.0888 | 0.0000 | 0.7054 | 1.0000 | 0.0003 | 0.0002 | 0.0009 | 0.0047 | 0.0314 | 0.0487 | 0.0382 | 0.0542 | 0.8214 | 10 | 12 | 15 | 20 | 34 | 52 | 79 | 150 | 276 | 0.1156 | 10.49 | 4.045 | 0.6216 | 27384.8 | 12500000 | 7130000000 | 4620000000000 | 0.4672 | 0.1594 | 0.0875 | 0.0139 | 0.2611 | 0.0541 | 0.2439 | 0.2073 | 0.1148 | 0.1314 | 0.0933 | 0.1294 | 0.0689 | 0.1208 | 0.0473 | 0.0812 | 0.0445 | 0.0759 | 0.0387 | 0.1861 | 0.0003 | 0.0020 | 0.0031 | 0.0022 | 0.0037 | 0.0053 | 0.0252 | 0.0193 | 0.0857 | 0.0735 | 0.1244 | 0.1092 | 0.0857 | 0.0732 | 0.1163 | 0.1151 | 0.5556 | 0.6003 | 0.0000 | 0.0000 | 0.0004 | 0.0010 | 0.0045 | 0.0077 | 0.0254 | 0.0305 | 0.0994 | 0.1056 | 0.1582 | 0.1608 | 0.0856 | 0.0944 | 0.1270 | 0.1370 | 0.4996 | 0.4630 | 0.0008 | 0.0044 | 0.0044 | 0.0252 | 0.0913 | 0.1442 | 0.0873 | 0.1197 | 0.5226 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 872 | 892 | | 3689 | 8762 | 488.5 | 108.21 | 84.63 | 135.98 | 344 | 390 | 427 | 458 | 489 | 518 | 545 | 576 | 623 | 0.0781 | 684 | 1.133 | 118.56 | 47.04 | 1 | 0.0848 | 313 | 0.0006 | 83.19 | 7.600 | 0.1213 | 250362.0 | 134000000 | 74800000000 | 43400000000000 | 0.4340 | 0.2055 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0009 | 0.0003 | 0.0153 | 0.0026 | 0.0610 | 0.0249 | 0.1194 | 0.0435 | 0.1225 | 0.0384 | 0.1500 | 0.0501 | 0.5305 | 0.8402 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0003 | 0.0075 | 0.0017 | 0.0282 | 0.0215 | 0.0411 | 0.0345 | 0.0380 | 0.0246 | 0.0598 | 0.0328 | 0.8247 | 0.8846 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0231 | 0.0000 | 0.0738 | 0.0000 | 0.1323 | 0.0000 | 0.1877 | 0.0000 | 0.1092 | 0.0000 | 0.1154 | 0.0000 | 0.3569 | 0.0000 | 0.0000 | 0.0011 | 0.0032 | 0.0151 | 0.0572 | 0.1068 | 0.0766 | 0.1176 | 0.6224 | 14 | 16 | 19 | 24 | 34 | 51 | 71 | 100 | 208 | 0.0576 | 11.33 | 4.133 | 0.6484 | 25648.9 | 14400000 | 10400000000 | 8570000000000 | 0.5629 | 0.1030 | 0.0175 | 0.0040 | 0.0903 | 0.0070 | 0.1233 | 0.0663 | 0.1155 | 0.0713 | 0.1291 | 0.1216 | 0.1107 | 0.1266 | 0.1097 | 0.1077 | 0.1175 | 0.1171 | 0.1864 | 0.3784 | 0.0014 | 0.0017 | 0.0025 | 0.0028 | 0.0076 | 0.0083 | 0.0245 | 0.0185 | 0.0736 | 0.0578 | 0.0848 | 0.0797 | 0.0704 | 0.0606 | 0.1050 | 0.0857 | 0.6301 | 0.6850 | 0.0011 | 0.0007 | 0.0011 | 0.0027 | 0.0080 | 0.0066 | 0.0218 | 0.0199 | 0.0856 | 0.0922 | 0.1287 | 0.1293 | 0.0666 | 0.0663 | 0.1034 | 0.1015 | 0.5836 | 0.5809 | 0.0042 | 0.0056 | 0.0075 | 0.0258 | 0.0714 | 0.1104 | 0.0770 | 0.0968 | 0.6012 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 346 | 701 | | 14198 | 40387 | 106.4 | 32.10 | 146.17 | 188.92 | 72 | 82 | 90 | 96 | 103 | 110 | 118 | 129 | 144 | 0.0393 | 1589 | 0.755 | 201.22 | 48.27 | 2 | 0.0373 | 529 | 0.0026 | 18.07 | 6.363 | 0.2881 | 12345.6 | 1580000 | 229000000 | 39000000000 | 0.4708 | 0.1852 | 0.0007 | 0.0001 | 0.0041 | 0.0010 | 0.0119 | 0.0011 | 0.0333 | 0.0042 | 0.0850 | 0.0218 | 0.1598 | 0.0539 | 0.1708 | 0.0533 | 0.1970 | 0.0847 | 0.3372 | 0.7798 | 0.0002 | 0.0000 | 0.0011 | 0.0001 | 0.0015 | 0.0003 | 0.0096 | 0.0013 | 0.0331 | 0.0130 | 0.0687 | 0.0281 | 0.0706 | 0.0210 | 0.1052 | 0.0352 | 0.7101 | 0.9010 | 0.0061 | 0.0103 | 0.0105 | 0.0240 | 0.0243 | 0.0326 | 0.0723 | 0.1021 | 0.1348 | 0.1501 | 0.1713 | 0.1827 | 0.1203 | 0.1226 | 0.1413 | 0.1389 | 0.3190 | 0.2367 | 0.0017 | 0.0051 | 0.0119 | 0.0353 | 0.0818 | 0.1125 | 0.1127 | 0.1276 | 0.5114 | 12 | 14 | 17 | 21 | 38 | 97 | 181 | 289 | 433 | 0.0636 | 63.25 | 5.587 | 0.4594 | 57055.8 | 29900000 | 18300000000 | 12600000000000 | 0.5337 | 0.1336 | 0.0936 | 0.0033 | 0.2406 | 0.0356 | 0.2573 | 0.2023 | 0.1157 | 0.1813 | 0.1154 | 0.1677 | 0.0874 | 0.1514 | 0.0464 | 0.0816 | 0.0283 | 0.0770 | 0.0152 | 0.0996 | 0.0002 | 0.0000 | 0.0009 | 0.0004 | 0.0022 | 0.0010 | 0.0084 | 0.0066 | 0.0488 | 0.0425 | 0.1001 | 0.0859 | 0.0667 | 0.0576 | 0.0957 | 0.0872 | 0.6770 | 0.7188 | 0.0006 | 0.0001 | 0.0009 | 0.0017 | 0.0039 | 0.0037 | 0.0107 | 0.0152 | 0.0648 | 0.0721 | 0.1272 | 0.1439 | 0.0905 | 0.0989 | 0.1204 | 0.1231 | 0.5809 | 0.5414 | 0.0005 | 0.0010 | 0.0023 | 0.0103 | 0.0565 | 0.1095 | 0.0807 | 0.1143 | 0.6250 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 309 | 287 | | 6693 | 13038 | 535.8 | 126.02 | 220.15 | 377.39 | 361 | 403 | 454 | 495 | 535 | 584 | 628 | 661 | 696 | 0.0639 | 833 | 0.910 | 75.03 | 22.56 | 1 | 0.0288 | 193 | 0.0006 | 30.06 | 7.569 | 0.2086 | 303013.0 | 179000000 | 110000000000 | 69800000000000 | 0.3886 | 0.2484 | 0.0015 | 0.0000 | 0.0045 | 0.0003 | 0.0063 | 0.0009 | 0.0218 | 0.0046 | 0.0499 | 0.0146 | 0.0646 | 0.0195 | 0.0738 | 0.0255 | 0.0999 | 0.0304 | 0.6777 | 0.9041 | 0.0002 | 0.0000 | 0.0006 | 0.0002 | 0.0000 | 0.0006 | 0.0040 | 0.0031 | 0.0151 | 0.0121 | 0.0173 | 0.0144 | 0.0213 | 0.0153 | 0.0279 | 0.0185 | 0.9136 | 0.9358 | 0.0000 | 0.0057 | 0.0066 | 0.0230 | 0.0119 | 0.0575 | 0.0328 | 0.0862 | 0.0519 | 0.1552 | 0.0781 | 0.1092 | 0.0972 | 0.1322 | 0.1151 | 0.1379 | 0.6064 | 0.2931 | 0.0003 | 0.0012 | 0.0018 | 0.0075 | 0.0221 | 0.0392 | 0.0374 | 0.0502 | 0.8404 | 9 | 11 | 13 | 16 | 29 | 82 | 190 | 352 | 702 | 0.1372 | 64.08 | 4.831 | 0.5651 | 190878.0 | 238000000 | 347000000000 | 556000000000000 | 0.2850 | 0.3373 | 0.0407 | 0.0012 | 0.1423 | 0.0098 | 0.1842 | 0.0952 | 0.1160 | 0.1173 | 0.1651 | 0.1419 | 0.1471 | 0.1751 | 0.0969 | 0.1204 | 0.0682 | 0.1106 | 0.0395 | 0.2285 | 0.0000 | 0.0000 | 0.0010 | 0.0002 | 0.0030 | 0.0007 | 0.0114 | 0.0099 | 0.0445 | 0.0399 | 0.0736 | 0.0527 | 0.0521 | 0.0432 | 0.0692 | 0.0647 | 0.7453 | 0.7886 | 0.0012 | 0.0003 | 0.0000 | 0.0010 | 0.0028 | 0.0059 | 0.0177 | 0.0200 | 0.0570 | 0.0596 | 0.0906 | 0.0950 | 0.0548 | 0.0665 | 0.0878 | 0.0871 | 0.6880 | 0.6646 | 0.0006 | 0.0008 | 0.0019 | 0.0171 | 0.0521 | 0.0803 | 0.0576 | 0.0745 | 0.7151 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1123 | 430 | | 9439 | 30387 | 187.6 | 49.18 | 85.43 | 137.20 | 127 | 150 | 163 | 176 | 187 | 199 | 211 | 226 | 249 | 0.0448 | 1360 | 0.978 | 133.06 | 44.05 | 3 | 0.0366 | 345 | 0.0011 | 36.27 | 7.174 | 0.1963 | 37625.0 | 7970000 | 1770000000 | 413000000000 | 0.4260 | 0.2189 | 0.0002 | 0.0000 | 0.0009 | 0.0001 | 0.0043 | 0.0007 | 0.0199 | 0.0027 | 0.0634 | 0.0169 | 0.1233 | 0.0399 | 0.1423 | 0.0401 | 0.1734 | 0.0580 | 0.4723 | 0.8415 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0016 | 0.0000 | 0.0072 | 0.0010 | 0.0225 | 0.0102 | 0.0434 | 0.0235 | 0.0516 | 0.0149 | 0.0628 | 0.0250 | 0.8102 | 0.9254 | 0.0063 | 0.0066 | 0.0083 | 0.0115 | 0.0276 | 0.0508 | 0.0683 | 0.0869 | 0.1017 | 0.1328 | 0.1424 | 0.1410 | 0.1226 | 0.1016 | 0.1346 | 0.1279 | 0.3881 | 0.3410 | 0.0009 | 0.0032 | 0.0071 | 0.0234 | 0.0626 | 0.0939 | 0.0934 | 0.1316 | 0.5841 | 10 | 12 | 14 | 16 | 20 | 29 | 62 | 140 | 267 | 0.1579 | 16.30 | 3.924 | 0.6407 | 26120.0 | 12600000 | 7750000000 | 5660000000000 | 0.5727 | 0.1271 | 0.1171 | 0.0076 | 0.2705 | 0.0420 | 0.2342 | 0.2186 | 0.1164 | 0.1757 | 0.1023 | 0.1567 | 0.0686 | 0.1384 | 0.0444 | 0.0856 | 0.0316 | 0.0752 | 0.0148 | 0.1002 | 0.0003 | 0.0005 | 0.0015 | 0.0008 | 0.0032 | 0.0031 | 0.0147 | 0.0133 | 0.0655 | 0.0528 | 0.0960 | 0.0906 | 0.0648 | 0.0549 | 0.0997 | 0.0876 | 0.6543 | 0.6964 | 0.0001 | 0.0004 | 0.0007 | 0.0004 | 0.0029 | 0.0039 | 0.0241 | 0.0258 | 0.0759 | 0.0823 | 0.1193 | 0.1295 | 0.0787 | 0.0827 | 0.1092 | 0.1138 | 0.5892 | 0.5612 | 0.0004 | 0.0010 | 0.0023 | 0.0194 | 0.0694 | 0.1084 | 0.0725 | 0.1053 | 0.6214 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 666 | 842 | | 12884 | 27221 | 219.0 | 58.92 | 118.73 | 205.47 | 152 | 171 | 185 | 199 | 212 | 227 | 245 | 268 | 298 | 0.0499 | 1359 | 0.808 | 193.62 | 44.05 | 2 | 0.0354 | 456 | 0.0008 | 46.64 | 7.460 | 0.1768 | 51441.8 | 12900000 | 3430000000 | 964000000000 | 0.4180 | 0.2281 | 0.0003 | 0.0001 | 0.0020 | 0.0000 | 0.0075 | 0.0004 | 0.0271 | 0.0027 | 0.0783 | 0.0206 | 0.1403 | 0.0412 | 0.1412 | 0.0459 | 0.1709 | 0.0684 | 0.4325 | 0.8207 | 0.0001 | 0.0000 | 0.0013 | 0.0000 | 0.0023 | 0.0000 | 0.0103 | 0.0014 | 0.0303 | 0.0115 | 0.0505 | 0.0181 | 0.0596 | 0.0180 | 0.0775 | 0.0275 | 0.7681 | 0.9236 | 0.0028 | 0.0068 | 0.0028 | 0.0184 | 0.0137 | 0.0261 | 0.0439 | 0.0812 | 0.0847 | 0.1285 | 0.1612 | 0.1865 | 0.1135 | 0.0889 | 0.1377 | 0.1449 | 0.4398 | 0.3188 | 0.0017 | 0.0044 | 0.0094 | 0.0269 | 0.0584 | 0.0906 | 0.0952 | 0.1178 | 0.5957 | 12 | 14 | 16 | 19 | 23 | 35 | 81 | 186 | 369 | 0.1090 | 28.98 | 4.298 | 0.6029 | 56311.6 | 43400000 | 43600000000 | 52400000000000 | 0.4887 | 0.1540 | 0.1380 | 0.0057 | 0.3027 | 0.0505 | 0.2534 | 0.2149 | 0.1170 | 0.1937 | 0.0888 | 0.2013 | 0.0605 | 0.1398 | 0.0282 | 0.0765 | 0.0105 | 0.0629 | 0.0008 | 0.0547 | 0.0000 | 0.0004 | 0.0018 | 0.0008 | 0.0016 | 0.0015 | 0.0149 | 0.0108 | 0.0607 | 0.0575 | 0.0912 | 0.0799 | 0.0683 | 0.0568 | 0.1015 | 0.0892 | 0.6600 | 0.7031 | 0.0005 | 0.0000 | 0.0008 | 0.0012 | 0.0040 | 0.0058 | 0.0208 | 0.0226 | 0.0784 | 0.0804 | 0.1103 | 0.1258 | 0.0842 | 0.0911 | 0.1132 | 0.1227 | 0.5879 | 0.5503 | 0.0004 | 0.0011 | 0.0027 | 0.0160 | 0.0680 | 0.1060 | 0.0721 | 0.1158 | 0.6178 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 420 | 742 | | 10935 | 36965 | 570.5 | 116.52 | 204.39 | 357.85 | 434 | 472 | 502 | 530 | 557 | 586 | 619 | 663 | 727 | 0.0445 | 1646 | 1.010 | 102.55 | 38.05 | 2 | 0.0258 | 282 | 0.0006 | 81.76 | 7.769 | 0.1488 | 339006.0 | 210000000 | 136000000000 | 92000000000000 | 0.4191 | 0.2288 | 0.0003 | 0.0000 | 0.0004 | 0.0000 | 0.0035 | 0.0003 | 0.0113 | 0.0011 | 0.0543 | 0.0126 | 0.1116 | 0.0285 | 0.1155 | 0.0282 | 0.1447 | 0.0456 | 0.5584 | 0.8837 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0011 | 0.0000 | 0.0039 | 0.0003 | 0.0256 | 0.0086 | 0.0516 | 0.0165 | 0.0554 | 0.0121 | 0.0712 | 0.0199 | 0.7907 | 0.9426 | 0.0034 | 0.0123 | 0.0069 | 0.0369 | 0.0195 | 0.0541 | 0.0653 | 0.1253 | 0.1146 | 0.1695 | 0.1725 | 0.1892 | 0.1135 | 0.0983 | 0.1358 | 0.1007 | 0.3685 | 0.2138 | 0.0006 | 0.0044 | 0.0105 | 0.0277 | 0.0720 | 0.1148 | 0.0938 | 0.1191 | 0.5571 | 6 | 8 | 9 | 11 | 14 | 35 | 134 | 381 | 754 | 0.1781 | 65.60 | 4.468 | 0.5873 | 169829.0 | 188000000 | 243000000000 | 352000000000000 | 0.4094 | 0.2312 | 0.1194 | 0.0037 | 0.3132 | 0.0514 | 0.3248 | 0.2365 | 0.1171 | 0.2139 | 0.0620 | 0.1913 | 0.0302 | 0.1403 | 0.0225 | 0.0740 | 0.0078 | 0.0503 | 0.0031 | 0.0385 | 0.0000 | 0.0000 | 0.0001 | 0.0002 | 0.0004 | 0.0009 | 0.0066 | 0.0033 | 0.0399 | 0.0364 | 0.0767 | 0.0693 | 0.0521 | 0.0427 | 0.0787 | 0.0708 | 0.7456 | 0.7764 | 0.0000 | 0.0000 | 0.0001 | 0.0003 | 0.0010 | 0.0015 | 0.0075 | 0.0101 | 0.0502 | 0.0538 | 0.0946 | 0.1037 | 0.0644 | 0.0702 | 0.0978 | 0.1071 | 0.6844 | 0.6533 | 0.0000 | 0.0002 | 0.0006 | 0.0068 | 0.0462 | 0.0827 | 0.0597 | 0.0911 | 0.7127 |
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 987 | 380 | | 12791 | 25828 | 244.0 | 56.67 | 95.18 | 198.31 | 177 | 201 | 217 | 230 | 243 | 256 | 271 | 289 | 316 | 0.0428 | 1106 | 0.611 | 50.00 | 6.08 | 2 | 0.0081 | 104 | 0.0009 | 41.29 | 7.385 | 0.1837 | 62748.8 | 16900000 | 4720000000 | 1370000000000 | 0.4150 | 0.2225 | 0.0007 | 0.0000 | 0.0010 | 0.0000 | 0.0040 | 0.0001 | 0.0139 | 0.0020 | 0.0437 | 0.0128 | 0.0935 | 0.0267 | 0.1037 | 0.0271 | 0.1485 | 0.0436 | 0.5911 | 0.8877 | 0.0004 | 0.0000 | 0.0005 | 0.0000 | 0.0012 | 0.0000 | 0.0051 | 0.0007 | 0.0167 | 0.0075 | 0.0370 | 0.0142 | 0.0370 | 0.0105 | 0.0578 | 0.0186 | 0.8443 | 0.9484 | 0.0051 | 0.0074 | 0.0136 | 0.0297 | 0.0230 | 0.0408 | 0.0519 | 0.1169 | 0.0928 | 0.1447 | 0.1328 | 0.1855 | 0.0992 | 0.1039 | 0.1507 | 0.1169 | 0.4308 | 0.2542 | 0.0013 | 0.0041 | 0.0084 | 0.0209 | 0.0523 | 0.0900 | 0.0917 | 0.1156 | 0.6157 | 10 | 11 | 13 | 16 | 19 | 30 | 61 | 128 | 252 | 0.1445 | 34.06 | 4.024 | 0.6355 | 48384.8 | 50100000 | 70500000000 | 115000000000000 | 0.4211 | 0.2561 | 0.0753 | 0.0013 | 0.2507 | 0.0276 | 0.3011 | 0.1619 | 0.1172 | 0.1639 | 0.1051 | 0.2101 | 0.0717 | 0.1905 | 0.0362 | 0.0921 | 0.0291 | 0.0768 | 0.0135 | 0.0758 | 0.0001 | 0.0002 | 0.0003 | 0.0001 | 0.0021 | 0.0012 | 0.0147 | 0.0116 | 0.0679 | 0.0616 | 0.1162 | 0.1005 | 0.0657 | 0.0596 | 0.1024 | 0.0930 | 0.6306 | 0.6721 | 0.0002 | 0.0012 | 0.0012 | 0.0028 | 0.0041 | 0.0058 | 0.0225 | 0.0271 | 0.0797 | 0.0776 | 0.1234 | 0.1387 | 0.0808 | 0.0856 | 0.1154 | 0.1264 | 0.5727 | 0.5349 | 0.0002 | 0.0013 | 0.0034 | 0.0168 | 0.0750 | 0.1186 | 0.0738 | 0.1066 | 0.6045 | ||
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 866 | 124 | | 7868 | 18298 | 509.3 | 103.27 | 71.24 | 63.85 | 380 | 418 | 450 | 475 | 502 | 530 | 561 | 596 | 645 | 0.0624 | 1141 | 1.024 | 98.60 | 36.00 | 1 | 0.0336 | 264 | 0.0007 | 43.87 | 7.460 | 0.1703 | 270039.0 | 149000000 | 85000000000 | 50300000000000 | 0.4294 | 0.2140 | 0.0004 | 0.0000 | 0.0011 | 0.0001 | 0.0029 | 0.0005 | 0.0116 | 0.0009 | 0.0506 | 0.0141 | 0.0958 | 0.0303 | 0.1076 | 0.0255 | 0.1326 | 0.0412 | 0.5975 | 0.8874 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0014 | 0.0001 | 0.0044 | 0.0005 | 0.0218 | 0.0097 | 0.0421 | 0.0212 | 0.0456 | 0.0141 | 0.0611 | 0.0214 | 0.8231 | 0.9329 | 0.0015 | 0.0151 | 0.0115 | 0.0075 | 0.0137 | 0.0491 | 0.0634 | 0.0943 | 0.0977 | 0.1698 | 0.1504 | 0.1698 | 0.1107 | 0.1132 | 0.1427 | 0.1208 | 0.4084 | 0.2604 | 0.0005 | 0.0021 | 0.0061 | 0.0192 | 0.0541 | 0.0908 | 0.0842 | 0.1111 | 0.6320 | 12 | 20 | 32 | 44 | 56 | 67 | 82 | 103 | 155 | 0.0160 | 5.43 | 4.946 | 0.5259 | 9151.3 | 1720000 | 410000000 | 113000000000 | 0.3977 | 0.2161 | 0.0063 | 0.0014 | 0.0287 | 0.0034 | 0.0848 | 0.0127 | 0.1175 | 0.0402 | 0.1734 | 0.0962 | 0.1759 | 0.1181 | 0.1582 | 0.1348 | 0.1455 | 0.1664 | 0.1097 | 0.4269 | 0.0011 | 0.0006 | 0.0036 | 0.0013 | 0.0059 | 0.0046 | 0.0190 | 0.0127 | 0.0462 | 0.0332 | 0.0641 | 0.0471 | 0.0697 | 0.0516 | 0.0984 | 0.0760 | 0.6920 | 0.7730 | 0.0018 | 0.0028 | 0.0049 | 0.0062 | 0.0101 | 0.0130 | 0.0352 | 0.0370 | 0.0677 | 0.0795 | 0.0948 | 0.0956 | 0.0883 | 0.0857 | 0.1176 | 0.1134 | 0.5795 | 0.5667 | 0.0029 | 0.0063 | 0.0092 | 0.0245 | 0.0550 | 0.0789 | 0.0782 | 0.1114 | 0.6337 | ||
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 607 | 425 | | 710 | 2523 | 137.3 | 19.50 | 92.60 | 84.78 | 108 | 118 | 127 | 136 | 142 | 146 | 151 | 155 | 160 | 0.1550 | 391 | 0.898 | 77.52 | 25.50 | 1 | 0.3000 | 213 | 0.0194 | 2.48 | 4.222 | 0.5165 | 19229.6 | 2740000 | 397000000 | 58100000000 | 0.3917 | 0.2405 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0116 | 0.0028 | 0.0547 | 0.0310 | 0.0547 | 0.0648 | 0.0813 | 0.0254 | 0.1360 | 0.0394 | 0.6617 | 0.8366 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0111 | 0.0028 | 0.0446 | 0.0310 | 0.0350 | 0.0648 | 0.0398 | 0.0254 | 0.0653 | 0.0394 | 0.8041 | 0.8366 | 0.1200 | 0.0000 | 0.2000 | 0.0000 | 0.3200 | 0.0000 | 0.0800 | 0.0000 | 0.2000 | 0.0000 | 0.0400 | 0.0000 | 0.0400 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0290 | 0.0338 | 0.0531 | 0.0628 | 0.0773 | 0.7440 | 21 | 29 | 40 | 53 | 69 | 84 | 105 | 131 | 195 | 0.0217 | 5.49 | 4.593 | 0.5505 | 15759.1 | 4090000 | 1360000000 | 524000000000 | 0.5327 | 0.1397 | 0.0216 | 0.0021 | 0.0747 | 0.0164 | 0.0943 | 0.0472 | 0.1179 | 0.0626 | 0.1473 | 0.1067 | 0.1866 | 0.1456 | 0.1218 | 0.1292 | 0.1257 | 0.1518 | 0.1100 | 0.3385 | 0.0000 | 0.0014 | 0.0085 | 0.0041 | 0.0136 | 0.0135 | 0.0298 | 0.0230 | 0.0562 | 0.0594 | 0.1285 | 0.0939 | 0.0809 | 0.0689 | 0.1260 | 0.1060 | 0.5566 | 0.6300 | 0.0030 | 0.0099 | 0.0120 | 0.0059 | 0.0150 | 0.0198 | 0.0435 | 0.0435 | 0.0901 | 0.1087 | 0.1667 | 0.1601 | 0.0901 | 0.1186 | 0.1396 | 0.1719 | 0.4399 | 0.3617 | 0.0056 | 0.0134 | 0.0134 | 0.0335 | 0.0838 | 0.1173 | 0.1039 | 0.1363 | 0.4927 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 525 | 784 | | 306 | 3162 | 64.0 | 11.66 | 117.65 | 178.73 | 49 | 52 | 58 | 61 | 64 | 67 | 70 | 74 | 79 | 0.1395 | 441 | 1.153 | 68.73 | 23.77 | 1 | 0.5556 | 170 | 0.0077 | 10.17 | 5.047 | 0.3110 | 4226.0 | 287862 | 20200000 | 1450000000 | 0.4562 | 0.1761 | 0.0000 | 0.0000 | 0.0147 | 0.0033 | 0.0196 | 0.0000 | 0.0686 | 0.0133 | 0.1520 | 0.0365 | 0.1765 | 0.1794 | 0.1520 | 0.0332 | 0.1912 | 0.1296 | 0.2255 | 0.6047 | 0.0000 | 0.0000 | 0.0118 | 0.0033 | 0.0039 | 0.0000 | 0.0433 | 0.0131 | 0.0630 | 0.0359 | 0.1299 | 0.1634 | 0.0591 | 0.0327 | 0.1378 | 0.0882 | 0.5512 | 0.6634 | 0.0400 | 0.0000 | 0.0000 | 0.0000 | 0.0800 | 0.0000 | 0.0600 | 0.8000 | 0.2200 | 0.2000 | 0.2000 | 0.0000 | 0.1400 | 0.0000 | 0.1400 | 0.0000 | 0.1200 | 0.0000 | 0.0062 | 0.0124 | 0.0248 | 0.0559 | 0.1242 | 0.0994 | 0.1242 | 0.1180 | 0.4348 | 11 | 12 | 13 | 15 | 18 | 44 | 106 | 220 | 400 | 0.1851 | 37.34 | 4.002 | 0.6018 | 45776.0 | 25200000 | 16900000000 | 13200000000000 | 0.6720 | 0.0567 | 0.1282 | 0.0081 | 0.1949 | 0.0782 | 0.2513 | 0.1240 | 0.1179 | 0.1563 | 0.1128 | 0.1725 | 0.0667 | 0.1590 | 0.0359 | 0.0755 | 0.0359 | 0.0916 | 0.0564 | 0.1348 | 0.0010 | 0.0000 | 0.0010 | 0.0009 | 0.0040 | 0.0027 | 0.0210 | 0.0153 | 0.0791 | 0.0694 | 0.1351 | 0.1127 | 0.1011 | 0.0902 | 0.1592 | 0.1461 | 0.4985 | 0.5627 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0012 | 0.0054 | 0.0348 | 0.0312 | 0.1057 | 0.1098 | 0.1480 | 0.1707 | 0.1294 | 0.1328 | 0.1654 | 0.1667 | 0.4142 | 0.3821 | 0.0011 | 0.0000 | 0.0033 | 0.0255 | 0.0909 | 0.1408 | 0.1098 | 0.1663 | 0.4623 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 735 | 406 | | 428 | 1601 | 77.0 | 10.85 | 11.27 | 14.00 | 65 | 67 | 70 | 72 | 75 | 77 | 82 | 86 | 93 | 0.1643 | 263 | 0.708 | 113.88 | 25.02 | 1 | 0.6636 | 284 | 0.0441 | 1.02 | 3.411 | 0.6516 | 6040.7 | 483894 | 39600000 | 3310000000 | 0.3996 | 0.2382 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0053 | 0.0024 | 0.0718 | 0.0447 | 0.1011 | 0.0753 | 0.0638 | 0.0400 | 0.1277 | 0.0918 | 0.6303 | 0.7435 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0047 | 0.0023 | 0.0498 | 0.0444 | 0.0687 | 0.0724 | 0.0332 | 0.0304 | 0.0782 | 0.0748 | 0.7654 | 0.7734 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0435 | 1.0000 | 0.0217 | 0.0000 | 0.1739 | 0.0000 | 0.1304 | 0.0000 | 0.1304 | 0.0000 | 0.1522 | 0.0000 | 0.3478 | 0.0000 | 0.0053 | 0.0000 | 0.0105 | 0.0474 | 0.0579 | 0.1000 | 0.0947 | 0.1263 | 0.5579 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 12 | 15 | 0.6009 | 2.10 | 1.178 | 0.8849 | 322.9 | 27681.3 | 3820000 | 619000000 | 0.6572 | 0.0788 | 0.0682 | 0.0020 | 0.1326 | 0.0188 | 0.1111 | 0.0683 | 0.1189 | 0.0960 | 0.1598 | 0.1317 | 0.1774 | 0.1545 | 0.1365 | 0.1535 | 0.0741 | 0.1723 | 0.0214 | 0.2030 | 0.0477 | 0.0017 | 0.0846 | 0.0145 | 0.0682 | 0.0513 | 0.0628 | 0.0803 | 0.1010 | 0.1103 | 0.1173 | 0.1350 | 0.1119 | 0.1325 | 0.1364 | 0.1556 | 0.2701 | 0.3188 | 0.0591 | 0.0313 | 0.0727 | 0.0313 | 0.0364 | 0.0313 | 0.0591 | 0.0625 | 0.0773 | 0.1188 | 0.1545 | 0.1688 | 0.1364 | 0.1813 | 0.1909 | 0.2125 | 0.2136 | 0.1625 | 0.0592 | 0.0547 | 0.0661 | 0.0957 | 0.1207 | 0.1276 | 0.1116 | 0.1344 | 0.2301 |