Live-cell imaging of cell-to-cell variability in caspase-8 FRET reporter activity and cell fate trajectory modeling - Dataset (ID:20232)

Data Columns

  • 19 Data Columns
Name Description Display Name Data Type Unit Precision Readout Type Replicate Comments
replicate Replicate Numeric 0
smallMolConcentration Small Mol Concentration Numeric 0
antibodyConcentration
Concentration of antibody agonist of DR4 or DR5
Antibody Concentration Numeric 1
proteinConcentration
Concentration of DR4/5 agonist
Protein Concentration Numeric 1
2ndAntibodyConcentration
Concentration of antibody clustering agent
2nd Antibody Concentration Numeric 1
meanlog10KAU
Average of the calculated log10(k) values (in arbitrary units) across all individual cells analyzed for a given treatment
Mean log10(k) (a.u.) Numeric 2
survivingFraction
Fraction of cells scored as viable 10 hours after treatment based on morphology
Surviving Fraction Numeric 3
meantauMin
Average of the calculated tau values (in min) across all individual cells analyzed for a given treatment
Mean tau (min) Numeric 4
classificationaccuracyFateBoundary
Fraction of cells properly classified as viable or inviable 10 hours after treatment based on the landscape of parameters k and tau
Classification Accuracy (fate boundary) Numeric 5
classificationaccuracyThetaT
Fraction of cells properly classified as viable or inviable 10 hours after treatment based on FRET reporter activation
Classification Accuracy (theta_T) Numeric 5
cell
Cell reagent
Cell cell
2ndAntibodyConcUnit 2nd Antibody Conc Unit Text
2ndAntibodyName 2nd Antibody Name Text
antibodyConcUnit Antibody Conc Unit Text
antibodyName Antibody Name Text
proteinConcUnit Protein Conc Unit Text
protein
Protein perturbagen
Protein protein
smallMolConcUnit Small Mol Conc Unit Text
smallMolecule
Small molecule perturbagen
Small Molecule small_molecule
  • 19 Data Columns