Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| GSK461364 | MDA-MB-175-VII | -4.4776 | 0.7103 | -4.6478 | -4.6477 | -4.9999 | 1.7670 | 0.0000 | 0.3335 | 7.1799 |
| GSK1838705A | HCC1143 | -4.1759 | 0.7093 | -5.5659 | -5.3897 | -5.5152 | 3.9450 | 0.3992 | 0.3992 | 7.5083 |
| NU6102 | SK-BR-3 | -4.1759 | 0.7066 | -3.9293 | -4.1759 | -4.5202 | 0.5514 | 0.0000 | 0.5776 | 8.0143 |
| Trametinib | CAMA-1 | -4.7773 | 0.7059 | -5.8873 | -4.7773 | -4.7773 | 0.5843 | 0.7967 | 0.8340 | 8.4439 |
| Pevonedistat | HCC2185 | -4.1759 | 0.7042 | -4.7199 | -4.1759 | -4.8044 | 3.9970 | 0.7577 | 0.7593 | 8.3530 |
| Baicalein | BT-474 | -3.7773 | 0.7040 | -4.2351 | -3.7773 | -3.9487 | 4.0000 | 0.7594 | 0.7629 | 9.0503 |
| Erlotinib | SUM52PE | -4.1759 | 0.7038 | -4.0735 | -4.1759 | -4.2670 | 1.6820 | 0.0011 | 0.5984 | 8.3275 |
| Everolimus | 600MPE | -4.1759 | 0.7026 | -3.6713 | -4.1759 | -4.6930 | 0.5121 | 0.0000 | 0.6445 | 8.2411 |
| Sunitinib | UACC-893 | -3.7773 | 0.7020 | -4.9393 | -4.8858 | -5.0728 | 3.9840 | 0.1943 | 0.1943 | 7.5005 |
| Gemcitabine | ZR75B | -3.8416 | 0.7019 | -7.6686 | -3.8416 | -7.4014 | 3.9460 | 0.7177 | 0.7177 | 7.4982 |
| CGC-11047 | HCC1395 | -2.3010 | 0.7018 | -3.4850 | -3.4848 | -4.2788 | 1.0160 | 0.0000 | 0.0590 | 6.2864 |
| Everolimus | 184B5 | -4.1759 | 0.7009 | -5.0564 | -5.0563 | NaN | 0.2937 | 0.0000 | 0.3554 | 6.4059 |
| Sigma A6730 | MDA-MB-231 | -4.1759 | 0.7005 | -4.7110 | -4.7109 | -4.7436 | 4.0000 | 0.0000 | 0.0072 | 9.0136 |
| CPT-11 | BT-474 | -4.0696 | 0.7000 | -5.0836 | -4.0696 | -5.0448 | 3.9800 | 0.7776 | 0.7776 | 8.9129 |