Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Sigma A6730 | HCC1569 | -4.1759 | 0.9583 | -4.8179 | -4.7859 | -5.0882 | 1.4515 | 0.0423 | 0.1479 | 7.5337 |
| Sigma A6730 | HCC1806 | -4.1759 | 0.9903 | -4.9814 | -4.9814 | -5.0839 | 2.1260 | 0.0000 | 0.0190 | 7.2872 |
| Sigma A6730 | HCC1937 | -4.1759 | 0.9431 | -4.8104 | -4.8104 | -5.0396 | 1.9990 | 0.0000 | 0.0511 | 7.2097 |
| Sigma A6730 | HCC1954 | -4.1759 | 0.9530 | -5.0232 | -5.0225 | -5.1425 | 2.3140 | 0.0022 | 0.0130 | 7.1331 |
| Sigma A6730 | HCC202 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Sigma A6730 | HCC38 | -4.1759 | 0.8843 | -4.8284 | -4.8283 | -4.9506 | 2.3505 | 0.0000 | 0.0319 | 7.0821 |
| Sigma A6730 | HCC70 | -4.1759 | 0.9504 | -5.3999 | -5.3965 | -5.7736 | 0.9793 | 0.0034 | 0.0634 | 6.6015 |
| Sigma A6730 | Hs 578T | -4.1759 | 0.9739 | -4.8110 | -4.8109 | -4.8932 | 2.1090 | 0.0000 | 0.0438 | 7.4401 |
| Sigma A6730 | MB 157 | -4.1759 | 0.8020 | -4.8682 | -4.8653 | -4.9110 | 3.9740 | 0.0130 | 0.0148 | 7.3056 |
| Sigma A6730 | MDA-MB-134-VI | -4.1759 | 0.9175 | -4.7669 | -4.7670 | -5.1323 | 2.1400 | 0.0000 | 0.0612 | 7.3376 |
| Sigma A6730 | MDA-MB-157 | -4.1759 | 0.9208 | -4.7613 | -4.7612 | -4.8427 | 4.0000 | 0.0001 | 0.0046 | 7.7546 |
| Sigma A6730 | MDA-MB-175-VII | -4.1759 | 0.9535 | -5.0331 | -5.0332 | -5.7470 | 1.2140 | 0.0000 | 0.0834 | 7.1844 |
| Sigma A6730 | MDA-MB-361 | -4.1759 | 0.9863 | -5.2799 | -5.2801 | -6.0459 | 1.0060 | 0.0000 | 0.0741 | 6.8148 |
| Sigma A6730 | MDA-MB-436 | -4.1759 | 0.8912 | -4.4922 | -4.4922 | -4.3132 | 2.3540 | 0.0000 | 0.1526 | 8.5230 |
| Sigma A6730 | MDA-MB-453 | -4.1759 | 0.9721 | -5.4519 | -5.4518 | -5.7281 | 1.4410 | 0.0000 | 0.0143 | 6.6250 |
| Sigma A6730 | MDA-MB-468 | -4.1759 | 0.9044 | -4.9020 | -4.9019 | -4.9932 | 1.2880 | 0.0000 | 0.1040 | 7.0804 |
| Sigma A6730 | T47D | -4.1759 | 0.9559 | -5.7389 | -5.4878 | -5.8139 | 1.0880 | 0.2333 | 0.2483 | 6.7452 |
| Sigma A6730 | UACC-812 | -4.1759 | 0.8191 | -4.9801 | -4.6862 | -5.5461 | 0.7077 | 0.0878 | 0.3422 | 7.3315 |
| Sigma A6730 | UACC-893 | -4.1759 | 0.9084 | -5.0650 | -5.0649 | -6.4435 | 1.0760 | 0.0000 | 0.0995 | 6.7347 |
| Sigma A6730 | ZR-75-1 | -4.1759 | 0.8786 | -5.2271 | -5.1490 | -6.1834 | 0.5509 | 0.0549 | 0.2948 | 6.7180 |
| Sigma A6730 | 184B5 | -4.1759 | 0.8439 | -5.3859 | -5.3864 | -5.6327 | 1.1690 | 0.0000 | 0.0370 | 6.3035 |
| Sigma A6730 | HCC1187 | -4.1759 | 0.9519 | -5.1336 | -5.1336 | -5.4641 | 1.0721 | 0.0000 | 0.0866 | 6.9207 |
| Sigma A6730 | MCF 10A | -4.1759 | 0.9265 | -5.2509 | -5.2511 | -5.3485 | 1.1130 | 0.0000 | 0.0598 | 6.9784 |
| Sigma A6730 | MCF 10F | -4.1759 | 0.9724 | -5.1739 | -5.1737 | -5.4463 | 0.9561 | 0.0000 | 0.1000 | 6.8338 |
| Sigma A6730 | SUM1315MO2 | -4.1759 | 0.9508 | -4.8908 | -4.8908 | -5.4137 | 1.5330 | 0.0000 | 0.0780 | 7.3004 |