Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.0533 | uM | 10419.087 | 0.5787 | -0.1033 | 0.6818 | |
| MDA-MB-134-VI | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.267 | uM | 10419.087 | 0.2388 | -0.7552 | 0.6818 | |
| MDA-MB-134-VI | HR+ | Luminal | Omipalisib | PI3K | PI3K | 1.33 | uM | 10419.087 | 0.0716 | -0.9581 | 0.6818 | |
| MDA-MB-134-VI | HR+ | Luminal | Omipalisib | PI3K | PI3K | 6.67 | uM | 10419.087 | 0.0303 | -0.9881 | 0.6818 | |
| MDA-MB-134-VI | HR+ | Luminal | Omipalisib | PI3K | PI3K | 33.3 | uM | 10419.087 | 0.0324 | -0.9869 | 0.6818 | |
| MDA-MB-134-VI | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 10519.087 | 0.9690 | 0.9396 | 1.0259 | |
| MDA-MB-134-VI | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.000427 | uM | 10519.087 | 0.9107 | 0.8258 | 1.0259 | |
| MDA-MB-134-VI | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.00213 | uM | 10519.087 | 0.9231 | 0.8500 | 1.0259 | |
| MDA-MB-134-VI | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.0107 | uM | 10519.087 | 0.7476 | 0.5062 | 1.0259 | |
| MDA-MB-134-VI | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.0533 | uM | 10519.087 | 0.5719 | 0.1600 | 1.0259 | |
| MDA-MB-134-VI | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.267 | uM | 10519.087 | 0.2166 | -0.5496 | 1.0259 | |
| MDA-MB-134-VI | HR+ | Luminal | Omipalisib | PI3K | PI3K | 1.33 | uM | 10519.087 | 0.0278 | -0.9390 | 1.0259 | |
| MDA-MB-134-VI | HR+ | Luminal | Omipalisib | PI3K | PI3K | 6.67 | uM | 10519.087 | 0.0147 | -0.9672 | 1.0259 | |
| MDA-MB-134-VI | HR+ | Luminal | Omipalisib | PI3K | PI3K | 33.3 | uM | 10519.087 | 0.0206 | -0.9547 | 1.0259 | |
| MDA-MB-157 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 7496.087 | 1.0194 | 1.0383 | 1.0123 | |
| MDA-MB-157 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.000427 | uM | 7496.087 | 0.9969 | 0.9939 | 1.0123 | |
| MDA-MB-157 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.00213 | uM | 7496.087 | 0.9915 | 0.9832 | 1.0123 | |
| MDA-MB-157 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0107 | uM | 7496.087 | 0.9757 | 0.9521 | 1.0123 | |
| MDA-MB-157 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0533 | uM | 7496.087 | 0.9351 | 0.8717 | 1.0123 | |
| MDA-MB-157 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.267 | uM | 7496.087 | 0.7923 | 0.5892 | 1.0123 | |
| MDA-MB-157 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 1.33 | uM | 7496.087 | 0.6025 | 0.2125 | 1.0123 | |
| MDA-MB-157 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 6.67 | uM | 7496.087 | 0.4746 | -0.0421 | 1.0123 | |
| MDA-MB-157 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 33.3 | uM | 7496.087 | 0.4292 | -0.1326 | 1.0123 | |
| MDA-MB-157 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 7498.086 | 1.0122 | 1.0233 | 1.0436 | |
| MDA-MB-157 | TNBC | Basal B | Omipalisib | PI3K | PI3K | 0.000427 | uM | 7498.086 | 0.9216 | 0.8495 | 1.0436 |