PF04217903 - Small Molecule (ID:10165-101)
| HMS LINCS ID: |
10165-101
|
| Name: | PF04217903 |
| Alternative Names: | |
| LINCS ID: | LSM-1166 |
| PubChem CID: | 17754438 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 372.14 |
| InChi: | InChI=1S/C19H16N8O/c28-7-6-26-12-15(9-22-26)17-10-21-18-19(23-17)27(25-24-18)11-13-3-4-16-14(8-13)2-1-5-20-16/h1-5,8-10,12,28H,6-7,11H2 |
| InChi Key: | PDMUGYOXRHVNMO-UHFFFAOYSA-N |
| SMILES: | C1=CC2=C(C=CC(=C2)CN3C4=NC(=CN=C4N=N3)C5=CN(N=C5)CCO)N=C1 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
MET | |
3 (equivalent to 1µM ≤ Kd < 10 µM) | ABL1, ACVR1, AIM1, ALK, AURKA, AURKB, BTK, CAMK1D, CAMK2A, CDK5, CDK7, CDK8, CDK9, CHEK1, CLK2, CLK4, CSF1R, CSNK1A1, DAPK3, DYRK1A, DYRK1B, FGFR1, FLG, FLT1, FLT3, FYN, GRK5, GSK3A, GSK3B, IGF1R, IKBKE, JAK2, JAK3, KDR, LCK, LIMK1, LRRK2, LTK, MAP2K1, MAP2K2, MAP4K2, MAP4K4, MAPK14, MAPK8, MAPK9, MST1R, NEK2, NTRK1, NTRK2, NTRK3, PAK4, PDE10A, PDE3A, PDE3B, PDE5A, PDGFRA, PDGFRB, PIM1, PRKAA1, PRKACA, PRKCQ, PRKD3, PRKX, PTK2, RET, ROCK1, RPS6KA3, TAOK1, TBK1, TNK2, TYRO3 |
10 (confirmed non-binding) |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10165-101-1 | Haoyuan chemexpress | HY-12017_1-20091026 |
(Kd <100 nM)