Kin237 - Small Molecule (ID:10113-101)
| HMS LINCS ID: |
10113-101
|
| Name: | Kin237 |
| Alternative Names: | Kin001-237; c-Met/Ron dual kinase inhibitor |
| LINCS ID: | LSM-1113 |
| PubChem CID: | 16757524 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 556.21 |
| InChi: | InChI=1S/C31H29FN4O5/c1-19-28(30(38)36(21-8-6-5-7-9-21)35(19)18-31(2,3)39)29(37)34-20-10-13-27(24(32)16-20)41-26-14-15-33-25-17-22(40-4)11-12-23(25)26/h5-17,39H,18H2,1-4H3,(H,34,37) |
| InChi Key: | UYMSIPINLJNNOU-UHFFFAOYSA-N |
| SMILES: | CC1=C(C(=O)N(N1CC(C)(C)O)C2=CC=CC=C2)C(=O)NC3=CC(=C(C=C3)OC4=C5C=CC(=CC5=NC=C4)OC)F |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
MET | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | IGF1R, MST1R |
3 (equivalent to 1µM ≤ Kd < 10 µM) | KDR |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10113-101-1 | Calbiochem |
(Kd <100 nM)